BMS 300 CERTIFICATION EVALUATION
TEST PAPER QUESTIONS AND SOLUTIONS
VERIFIED COMPLETE
●● What sex determinants are present in males (XY)?
Answer: Sry and Sox9
●● Primoridal Germ Cell (PGC) differentiation in XX
Answer: Mesonephros --> Retinoic Acid --> Gonad --> no CYP26B1 --
> Meiotic entry PGCs
●● Primoridal Germ Cell (PGC) differentiation in XY
Answer: Mesonephros --> Retinoic Acid --> Gonad -->CYP26B1 --> No
Meiotic entry PGCs
●● True or False? Primary/Gonad sex differentiation does NOT depend
on PGC differentiation.
Answer: True
●● Created by Wolffian Duct
Answer: Epididymis (Testis), Vas Deferenes, Seminal Vesicle
, ●● Created by Mullerian Duct
Answer: Ovary (Oviduct/"Fallopian Tube"), Uterus, Upper 1/3 of Vagina
●● Removing the gonads of rabbits shows us that:
Answer: The ovary does not do anything in development
●● Removing the gonads of rabbits, and adding testosterone shows us
that:
Answer: Male development relies greatly on testosterone.
●● Removing the gonads of rabbits and taking testis fragments, and
putting them back in, shows us that:
Answer: Anti-Mullerian Hormone is present and secreted by Sertoli cells
and gets ride of the Mullerian Duct.
●● Development of external genitalia can be bi-potential. Bi-potential
means that:
Answer: Either one of the two outcomes is possible, it just depends on
the factors present, and what is released, and what is blocked.
●● Androgen Insensitivity Syndrome (testicular feminization syndrome)
Answer: Mutation in androgen receptor that causes:
Chromosomal Sex: XX
TEST PAPER QUESTIONS AND SOLUTIONS
VERIFIED COMPLETE
●● What sex determinants are present in males (XY)?
Answer: Sry and Sox9
●● Primoridal Germ Cell (PGC) differentiation in XX
Answer: Mesonephros --> Retinoic Acid --> Gonad --> no CYP26B1 --
> Meiotic entry PGCs
●● Primoridal Germ Cell (PGC) differentiation in XY
Answer: Mesonephros --> Retinoic Acid --> Gonad -->CYP26B1 --> No
Meiotic entry PGCs
●● True or False? Primary/Gonad sex differentiation does NOT depend
on PGC differentiation.
Answer: True
●● Created by Wolffian Duct
Answer: Epididymis (Testis), Vas Deferenes, Seminal Vesicle
, ●● Created by Mullerian Duct
Answer: Ovary (Oviduct/"Fallopian Tube"), Uterus, Upper 1/3 of Vagina
●● Removing the gonads of rabbits shows us that:
Answer: The ovary does not do anything in development
●● Removing the gonads of rabbits, and adding testosterone shows us
that:
Answer: Male development relies greatly on testosterone.
●● Removing the gonads of rabbits and taking testis fragments, and
putting them back in, shows us that:
Answer: Anti-Mullerian Hormone is present and secreted by Sertoli cells
and gets ride of the Mullerian Duct.
●● Development of external genitalia can be bi-potential. Bi-potential
means that:
Answer: Either one of the two outcomes is possible, it just depends on
the factors present, and what is released, and what is blocked.
●● Androgen Insensitivity Syndrome (testicular feminization syndrome)
Answer: Mutation in androgen receptor that causes:
Chromosomal Sex: XX