BMS 300 TEST BANK COMPLETE SOLVED
QUESTIONS EXPERT REVIEW FULL
SOLUTION
●● The Bark Scorpion, is a highly venomous scorpion of Arizona. Its
sting is exceptionally painful to mammals, yet the Grasshopper Mouse
readily preys on these arachnids. Videos show the mice being stung
repeatedly without demonstrating pain. Molecular analyses of the mouse
show a single amino acid change in a voltage-gated channel specific to
pain sensing neurons in the peripheral nervous system; the scorpion
toxin binds to this channel, and prevents it from opening. This mutation
allows the Grasshopper Mouse to be stung by the scorpion, but feel no
pain.
Assuming uniform distribution of the scorpion toxin in the central and
peripheral nervous system, you would expect labeled scorpion toxin to
be found:
Answer: At the nodes of Ranvier of myelinated neurons
●● The Bark Scorpion, is a highly venomous scorpion of Arizona. Its
sting is exceptionally painful to mammals, yet the Grasshopper Mouse
readily preys on these arachnids. Videos show the mice being stung
repeatedly without demonstrating pain. Molecular analyses of the mouse
show a single amino acid change in a voltage-gated channel specific to
pain sensing neurons in the peripheral nervous system; the scorpion
toxin binds to this channel, and prevents it from opening. This mutation
,allows the Grasshopper Mouse to be stung by the scorpion, but feel no
pain.
In comparison to a normal house mouse:
Answer: -The Grasshopper Mouse would lack action potentials in the
second order neuron produced by a pin prick
-The Grasshopper Mouse would lack action potentials produced by the
scorpion venom in the pain sensitive primary sensory afferent
●● The Bark Scorpion, is a highly venomous scorpion of Arizona. Its
sting is exceptionally painful to mammals, yet the Grasshopper Mouse
readily preys on these arachnids. Videos show the mice being stung
repeatedly without demonstrating pain. Molecular analyses of the mouse
show a single amino acid change in a voltage-gated channel specific to
pain sensing neurons in the peripheral nervous system; the scorpion
toxin binds to this channel, and prevents it from opening. This mutation
allows the Grasshopper Mouse to be stung by the scorpion, but feel no
pain.
In mice other than the Grasshopper Mouse, action potentials would
propagate toward the brain in the spinal cord in the :
Answer: Spinothalamic tract
●● The Bark Scorpion, is a highly venomous scorpion of Arizona. Its
sting is exceptionally painful to mammals, yet the Grasshopper Mouse
readily preys on these arachnids. Videos show the mice being stung
, repeatedly without demonstrating pain. Molecular analyses of the mouse
show a single amino acid change in a voltage-gated channel specific to
pain sensing neurons in the peripheral nervous system; the scorpion
toxin binds to this channel, and prevents it from opening. This mutation
allows the Grasshopper Mouse to be stung by the scorpion, but feel no
pain.
The toxin in the Bark Scorpion venom most likely binds to a:
Answer: -Primary sensory afferent
-a neuron that forms its first synapse in the dorsal horn of the spinal cord
●● The Bark Scorpion, is a highly venomous scorpion of Arizona. Its
sting is exceptionally painful to mammals, yet the Grasshopper Mouse
readily preys on these arachnids. Videos show the mice being stung
repeatedly without demonstrating pain. Molecular analyses of the mouse
show a single amino acid change in a voltage-gated channel specific to
pain sensing neurons in the peripheral nervous system; the scorpion
toxin binds to this channel, and prevents it from opening. This mutation
allows the Grasshopper Mouse to be stung by the scorpion, but feel no
pain.
The ion most likely prevented from flowing through this channel by the
toxin is:
Answer: Na+
QUESTIONS EXPERT REVIEW FULL
SOLUTION
●● The Bark Scorpion, is a highly venomous scorpion of Arizona. Its
sting is exceptionally painful to mammals, yet the Grasshopper Mouse
readily preys on these arachnids. Videos show the mice being stung
repeatedly without demonstrating pain. Molecular analyses of the mouse
show a single amino acid change in a voltage-gated channel specific to
pain sensing neurons in the peripheral nervous system; the scorpion
toxin binds to this channel, and prevents it from opening. This mutation
allows the Grasshopper Mouse to be stung by the scorpion, but feel no
pain.
Assuming uniform distribution of the scorpion toxin in the central and
peripheral nervous system, you would expect labeled scorpion toxin to
be found:
Answer: At the nodes of Ranvier of myelinated neurons
●● The Bark Scorpion, is a highly venomous scorpion of Arizona. Its
sting is exceptionally painful to mammals, yet the Grasshopper Mouse
readily preys on these arachnids. Videos show the mice being stung
repeatedly without demonstrating pain. Molecular analyses of the mouse
show a single amino acid change in a voltage-gated channel specific to
pain sensing neurons in the peripheral nervous system; the scorpion
toxin binds to this channel, and prevents it from opening. This mutation
,allows the Grasshopper Mouse to be stung by the scorpion, but feel no
pain.
In comparison to a normal house mouse:
Answer: -The Grasshopper Mouse would lack action potentials in the
second order neuron produced by a pin prick
-The Grasshopper Mouse would lack action potentials produced by the
scorpion venom in the pain sensitive primary sensory afferent
●● The Bark Scorpion, is a highly venomous scorpion of Arizona. Its
sting is exceptionally painful to mammals, yet the Grasshopper Mouse
readily preys on these arachnids. Videos show the mice being stung
repeatedly without demonstrating pain. Molecular analyses of the mouse
show a single amino acid change in a voltage-gated channel specific to
pain sensing neurons in the peripheral nervous system; the scorpion
toxin binds to this channel, and prevents it from opening. This mutation
allows the Grasshopper Mouse to be stung by the scorpion, but feel no
pain.
In mice other than the Grasshopper Mouse, action potentials would
propagate toward the brain in the spinal cord in the :
Answer: Spinothalamic tract
●● The Bark Scorpion, is a highly venomous scorpion of Arizona. Its
sting is exceptionally painful to mammals, yet the Grasshopper Mouse
readily preys on these arachnids. Videos show the mice being stung
, repeatedly without demonstrating pain. Molecular analyses of the mouse
show a single amino acid change in a voltage-gated channel specific to
pain sensing neurons in the peripheral nervous system; the scorpion
toxin binds to this channel, and prevents it from opening. This mutation
allows the Grasshopper Mouse to be stung by the scorpion, but feel no
pain.
The toxin in the Bark Scorpion venom most likely binds to a:
Answer: -Primary sensory afferent
-a neuron that forms its first synapse in the dorsal horn of the spinal cord
●● The Bark Scorpion, is a highly venomous scorpion of Arizona. Its
sting is exceptionally painful to mammals, yet the Grasshopper Mouse
readily preys on these arachnids. Videos show the mice being stung
repeatedly without demonstrating pain. Molecular analyses of the mouse
show a single amino acid change in a voltage-gated channel specific to
pain sensing neurons in the peripheral nervous system; the scorpion
toxin binds to this channel, and prevents it from opening. This mutation
allows the Grasshopper Mouse to be stung by the scorpion, but feel no
pain.
The ion most likely prevented from flowing through this channel by the
toxin is:
Answer: Na+
