NCLEX Pharmacology Practice Exam 2026–2027 Comprehensive Study Guide • 250 Original Practice Questions • 15 NGN-Style Case Studies • Detailed Rationales

NCLEX Pharmacology Practice Exam 2026–2027

Comprehensive Study Guide • 250 Original Practice
Questions • 15 NGN-Style Case Studies • Detailed Rationales




NCLEX PHARMACOLOGY PRACTICE EXAM 2026–2027

Comprehensive Study Guide • 250 Original Practice
Questions • 15 NGN-Style Case Studies • Detailed Rationales



Prepared by: Expert Nursing Educators

For: Nursing Students Preparing for NCLEX-RN® and NCLEX-PN® Pharmacology
Examinations

Edition: 2026–2027




This study guide contains original NCLEX-style practice questions and is designed to
supplement your nursing education. It is not affiliated with, endorsed by, or approved by
NCSBN, Elsevier, ATI, Pearson, or any nursing school. These questions are practice
materials only and do not guarantee success on any official examination.

,DISCLAIMER



IMPORTANT NOTICE TO STUDENTS

This study guide is an independent educational resource created by nursing educators
to assist students in preparing for NCLEX-style pharmacology examinations.

This guide is NOT:

• A collection of actual, leaked, or recalled NCLEX examination questions
• Affiliated with, endorsed by, or approved by NCSBN, Elsevier, ATI, Pearson, or any
nursing school
• A guarantee of passing any official nursing examination
• A substitute for formal nursing education, clinical experience, or comprehensive
exam preparation

This guide IS:

• Original practice questions written by experienced nursing educators
• Designed to strengthen pharmacology knowledge, clinical reasoning, and test-
taking skills
• Based on publicly available nursing education standards and competency
frameworks
• Intended as a supplementary study tool

Nursing Practice Acknowledgment:

All clinical scenarios, medication dosages, and nursing interventions presented in this
guide are for educational practice purposes only. They do not constitute medical advice,
clinical guidelines, or protocols for actual patient care.

Exam Performance Disclaimer:

Success on any nursing examination depends on multiple factors. This guide does not
guarantee any specific examination outcome.

,Educational Use Only:

This material is intended for individual study use by nursing students. Reproduction,
distribution, or commercial use without explicit permission is prohibited.




By using this study guide, you acknowledge that you have read and understand
this disclaimer.




TABLE OF CONTENTS



COVER PAGE ............................................................................................................. 1

DISCLAIMER ............................................................................................................. 2

TABLE OF CONTENTS .............................................................................................. 3

HOW TO USE THIS GUIDE ....................................................................................... 6




PART 1 — PHARMACOLOGY REVIEW
1. Pharmacology Fundamentals ............................................................................... 8

• Pharmacokinetics (ADME)
• Pharmacodynamics
• Drug Naming and Classification
• Medication Rights and Safety

2. Drug Suffixes and Classifications ....................................................................... 12

, • Cardiovascular Suffixes
• Anti-Infective Suffixes
• CNS and Psychiatric Suffixes
• Endocrine Suffixes
• GI and Respiratory Suffixes

3. Cardiovascular Medications ............................................................................... 16

• Beta Blockers
• ACE Inhibitors
• ARBs
• Calcium Channel Blockers
• Diuretics
• Cardiac Glycosides
• Anticoagulants
• Antiplatelets
• Statins
• Nitrates

4. Anti-Infective Medications ................................................................................. 22

• Penicillins
• Cephalosporins
• Macrolides
• Aminoglycosides
• Fluoroquinolones
• Tetracyclines
• Antifungals
• Antivirals

5. Endocrine Medications ...................................................................................... 26

• Insulins
• Oral Antidiabetics
• Thyroid Medications
• Corticosteroids

6. Neurological and Psychiatric Medications .......................................................... 30

• Antidepressants (SSRI, SNRI, TCA, MAOI)
• Antipsychotics
• Mood Stabilizers (Lithium)