COMSAE EXAM PREP QUESTIONS ANSWERS STUDY GUIDE VERIFIED SOLUTION
Question:
Which Ovarian Tumor?
Answer:
Tumor markers are hCG, LDH Associated with Turner Syndrome Sheets of uniform cells Large
Cells with clear cytoplasm and central nuclei (egg-like)
Question:
Most common malignant germ cell tumor
Answer:
Dysgerminoma Which Ovarian Tumor? malignancy of trophoblastic tissue chorionic villi are NOT
present. increased frequency of theca-lutein cysts Early Hematogenous spread to lungs.
Question:
Tumor marker is hCG.
Answer:
Choriocarcinoma Which Ovarian Tumor? Yellow, friable, solid masses Schiller-Duval bodies
(resemble glomeruli)
Question:
makes AFP
Answer:
Yolk sac (endodermal sinus) tumor Which Tumor?
Question:
,2 or 3 germ layers.
Answer:
Teratoma
Question:
contains functional thyroid tissue can present as hyperthyroidism.
Answer:
Struma ovarii Which tumor? looks like bladder (contains urothelium) pale yellow-tan in color
appears encapsulated
Question:
coffee bean* nuclei on H&E staining.
Answer:
Brenner Tumor What tumor? primary GI malignancy that metastasizes to the ovaries -> causing
mucin secreting signet cell adenocarcinoma
Question:
signet cells
Answer:
Krukenberg tumor What tumor? fallopian tube-like epithelium
Question:
single cyst with flat lining
Answer:
Serous Cystadenoma
Question:
, General ovarian cancer marker
Answer:
CA-125 What tumor? cystic and is from surface epithelium psammoma bodies risk factors include
BRCA - 1 BRCA - 2 and HNPCC malignant clear invasion of cells in CT
Question:
larger tumor with complicated cysts with thick shaggy lining. *
Answer:
Serous Cystadenocarcinoma What tumor? mucous, from surface epithelium multiocular cyst
Question:
benign, intestine like tissue.
Answer:
Mucinous Cystadenoma What tumor?
Question:
pseudomyxoma peritonei (jelly belly - appendix)
Answer:
Mucinous Cystadenocarcinoma What tumor? Meig's Triad ("answer to this card", ascites and
hydrothorax)
Question:
bundles of spindle shaped fibroblasts
Answer:
Fibromas What tumor? secretes estrogen = precocious puberty in young kids & can cause
endometrial hyperplasia or carcinoma in adults Call-exner bodies (small follicles filled with
eosinophilic secretions.)
Question:
Which Ovarian Tumor?
Answer:
Tumor markers are hCG, LDH Associated with Turner Syndrome Sheets of uniform cells Large
Cells with clear cytoplasm and central nuclei (egg-like)
Question:
Most common malignant germ cell tumor
Answer:
Dysgerminoma Which Ovarian Tumor? malignancy of trophoblastic tissue chorionic villi are NOT
present. increased frequency of theca-lutein cysts Early Hematogenous spread to lungs.
Question:
Tumor marker is hCG.
Answer:
Choriocarcinoma Which Ovarian Tumor? Yellow, friable, solid masses Schiller-Duval bodies
(resemble glomeruli)
Question:
makes AFP
Answer:
Yolk sac (endodermal sinus) tumor Which Tumor?
Question:
,2 or 3 germ layers.
Answer:
Teratoma
Question:
contains functional thyroid tissue can present as hyperthyroidism.
Answer:
Struma ovarii Which tumor? looks like bladder (contains urothelium) pale yellow-tan in color
appears encapsulated
Question:
coffee bean* nuclei on H&E staining.
Answer:
Brenner Tumor What tumor? primary GI malignancy that metastasizes to the ovaries -> causing
mucin secreting signet cell adenocarcinoma
Question:
signet cells
Answer:
Krukenberg tumor What tumor? fallopian tube-like epithelium
Question:
single cyst with flat lining
Answer:
Serous Cystadenoma
Question:
, General ovarian cancer marker
Answer:
CA-125 What tumor? cystic and is from surface epithelium psammoma bodies risk factors include
BRCA - 1 BRCA - 2 and HNPCC malignant clear invasion of cells in CT
Question:
larger tumor with complicated cysts with thick shaggy lining. *
Answer:
Serous Cystadenocarcinoma What tumor? mucous, from surface epithelium multiocular cyst
Question:
benign, intestine like tissue.
Answer:
Mucinous Cystadenoma What tumor?
Question:
pseudomyxoma peritonei (jelly belly - appendix)
Answer:
Mucinous Cystadenocarcinoma What tumor? Meig's Triad ("answer to this card", ascites and
hydrothorax)
Question:
bundles of spindle shaped fibroblasts
Answer:
Fibromas What tumor? secretes estrogen = precocious puberty in young kids & can cause
endometrial hyperplasia or carcinoma in adults Call-exner bodies (small follicles filled with
eosinophilic secretions.)
