, a LANGE medical book
Vander’s Renal
Physiology
Eighth Edition
Douglas C. Eaton, PhD
Distinguished Professor of Physiology
and Professor of Pediatrics
Department of Physiology
Emory University School of Medicine
Atlanta, Georgia
John P. Pooler, PhD
Professor of Physiology Emeritus
Department of Physiology
Emory University School of Medicine
Atlanta, Georgia
New York Chicago San Francisco Lisbon London Madrid Mexico City
,Milan New Delhi San Juan Seoul Singapore Sydney Toronto
, Copyright © 2013 by McGraw-Hill Education, LLC. All rights reserved. Except as permitted under the
United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any
form or by any means, or stored in a database or retrieval system, without the prior written permission
of the publisher.
ISBN: 978-0-07-179749-8
MHID: 0-07-179749-1
The material in this eBook also appears in the print version of this title: ISBN: 978-0-07-179748-1,
MHID: 0-07-179748-3.
All trademarks are trademarks of their respective owners. Rather than put a trademark symbol after every
occurrence of a trademarked name, we use names in an editorial fashion only, and to the benefit of the
trademark owner, with no intention of infringement of the trademark. Where such designations appear in
this book, they have been printed with initial caps.
McGraw-Hill Education eBooks are available at special quantity discounts to use as premiums and sales
promotions, or for use in corporate training programs. To contact a representative please e-mail us at
.
Notice
Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge,
changes in treatment and drug therapy are required. The authors and the publisher of this work have
checked with sources believed to be reliable in their efforts to provide information that is complete
and generally in accord with the standards accepted at the time of publication. However, in view of the
possibility of human error or changes in medical sciences, neither the authors nor the publisher nor
any other party who has been involved in the preparation or publication of this work warrants that the
information contained herein is in every respect accurate or complete, and they disclaim all responsibility
for any errors or omissions or for the results obtained from use of the information contained in this work.
Readers are encouraged to confirm the information contained herein with other sources. For example and
in particular, readers are advised to check the product information sheet included in the package of each
drug they plan to administer to be certain that the information contained in this work is accurate and that
changes have not been made in the recommended dose or in the contraindications for administration.
This recommendation is of particular importance in connection with new or infrequently used drugs.
TERMS OF USE
This is a copyrighted work and McGraw-Hill Education, LLC. and its licensors reserve all rights in and
to the work. Use of this work is subject to these terms. Except as permitted under the Copyright Act
of 1976 and the right to store and retrieve one copy of the work, you may not decompile, disassemble,
reverse engineer, reproduce, modify, create derivative works based upon, transmit, distribute,
disseminate, sell, publish or sublicense the work or any part of it without McGraw-Hill Education’s prior
consent. You may use the work for your own noncommercial and personal use; any other use of the work
is strictly prohibited. Your right to use the work may be terminated if you fail to comply with these terms.
THE WORK IS PROVIDED “AS IS.” McGRAW-HILL EDUCATION AND ITS LICENSORS
MAKE NO GUARANTEES OR WARRANTIES AS TO THE ACCURACY, ADEQUACY OR
COMPLETENESS OF OR RESULTS TO BE OBTAINED FROM USING THE WORK,
INCLUDING ANY INFORMATION THAT CAN BE ACCESSED THROUGH THE WORK
VIA HYPERLINK OR OTHERWISE, AND EXPRESSLY DISCLAIM ANY WARRANTY,
EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO IMPLIED WARRANTIES OF
MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. McGraw-Hill Education
and its licensors do not warrant or guarantee that the functions contained in the work will meet your
Vander’s Renal
Physiology
Eighth Edition
Douglas C. Eaton, PhD
Distinguished Professor of Physiology
and Professor of Pediatrics
Department of Physiology
Emory University School of Medicine
Atlanta, Georgia
John P. Pooler, PhD
Professor of Physiology Emeritus
Department of Physiology
Emory University School of Medicine
Atlanta, Georgia
New York Chicago San Francisco Lisbon London Madrid Mexico City
,Milan New Delhi San Juan Seoul Singapore Sydney Toronto
, Copyright © 2013 by McGraw-Hill Education, LLC. All rights reserved. Except as permitted under the
United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any
form or by any means, or stored in a database or retrieval system, without the prior written permission
of the publisher.
ISBN: 978-0-07-179749-8
MHID: 0-07-179749-1
The material in this eBook also appears in the print version of this title: ISBN: 978-0-07-179748-1,
MHID: 0-07-179748-3.
All trademarks are trademarks of their respective owners. Rather than put a trademark symbol after every
occurrence of a trademarked name, we use names in an editorial fashion only, and to the benefit of the
trademark owner, with no intention of infringement of the trademark. Where such designations appear in
this book, they have been printed with initial caps.
McGraw-Hill Education eBooks are available at special quantity discounts to use as premiums and sales
promotions, or for use in corporate training programs. To contact a representative please e-mail us at
.
Notice
Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge,
changes in treatment and drug therapy are required. The authors and the publisher of this work have
checked with sources believed to be reliable in their efforts to provide information that is complete
and generally in accord with the standards accepted at the time of publication. However, in view of the
possibility of human error or changes in medical sciences, neither the authors nor the publisher nor
any other party who has been involved in the preparation or publication of this work warrants that the
information contained herein is in every respect accurate or complete, and they disclaim all responsibility
for any errors or omissions or for the results obtained from use of the information contained in this work.
Readers are encouraged to confirm the information contained herein with other sources. For example and
in particular, readers are advised to check the product information sheet included in the package of each
drug they plan to administer to be certain that the information contained in this work is accurate and that
changes have not been made in the recommended dose or in the contraindications for administration.
This recommendation is of particular importance in connection with new or infrequently used drugs.
TERMS OF USE
This is a copyrighted work and McGraw-Hill Education, LLC. and its licensors reserve all rights in and
to the work. Use of this work is subject to these terms. Except as permitted under the Copyright Act
of 1976 and the right to store and retrieve one copy of the work, you may not decompile, disassemble,
reverse engineer, reproduce, modify, create derivative works based upon, transmit, distribute,
disseminate, sell, publish or sublicense the work or any part of it without McGraw-Hill Education’s prior
consent. You may use the work for your own noncommercial and personal use; any other use of the work
is strictly prohibited. Your right to use the work may be terminated if you fail to comply with these terms.
THE WORK IS PROVIDED “AS IS.” McGRAW-HILL EDUCATION AND ITS LICENSORS
MAKE NO GUARANTEES OR WARRANTIES AS TO THE ACCURACY, ADEQUACY OR
COMPLETENESS OF OR RESULTS TO BE OBTAINED FROM USING THE WORK,
INCLUDING ANY INFORMATION THAT CAN BE ACCESSED THROUGH THE WORK
VIA HYPERLINK OR OTHERWISE, AND EXPRESSLY DISCLAIM ANY WARRANTY,
EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO IMPLIED WARRANTIES OF
MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. McGraw-Hill Education
and its licensors do not warrant or guarantee that the functions contained in the work will meet your
