ANCC Informatics Nursing Certification Examination (NI-BC®) Practice Question
Bank
Table of Contents
Section Content Domain Question Numbers
I Foundations of Practice 1 – 54
I.A Professional Practice 1 – 12
I.B Methodologies and Theories 13 – 27
I.C Rules, Regulations, and Requirements 28 – 42
I.D Interprofessional Collaboration 43 – 54
II System Design Lifecycle 55 – 103
II.A Planning and Analysis 55 – 67
II.B Designing and Building 68 – 80
II.C Testing, Training, and Implementation 81 – 93
Monitoring, Maintaining, Supporting, and
II.D 94 – 103
Evaluating
III Data Management and Healthcare Technology 104 – 150
III.A Data Standards and Terminology 104 – 116
III.B Data Management and Analytics 117 – 129
III.C Healthcare Technology and Clinical Systems 130 – 140
III.D Security, Privacy, and Interoperability 141 – 150
SECTION I: FOUNDATIONS OF PRACTICE (45 Questions)
I.A: Professional Practice
• Q1. The American Nurses Association (ANA) recognizes nursing informatics as a specialty that integrates nursing science with which
of the following foundational sciences?
🟢 A. Computer science and library science
🟢 B. Information science and computer science
🟢 C. Cognitive science and systems science
🟢 D. Data science and engineering
🔴🔴 Correct Answer: B
,Rationale: The ANA defines nursing informatics as the specialty that integrates nursing science with information science and computer
science to manage and communicate data, information, knowledge, and wisdom in nursing practice. This tripartite foundation
distinguishes nursing informatics from other health informatics disciplines.
• Q2. A nurse informaticist is developing a strategic plan for implementing a new clinical documentation system across a multi-
hospital system. Which management function is the informaticist primarily demonstrating?
🟢 A. Budgeting only
🟢 B. Strategic planning
🟢 C. Mentoring
🟢 D. Policy promotion
🔴🔴 Correct Answer: B
Rationale: Strategic planning is a core management fundamental in informatics nursing practice that involves developing long-term
direction and resource allocation for technology initiatives. The scenario describes the informaticist engaged in high-level planning
across the organization, which exemplifies strategic planning rather than the other options.
• Q3. Which of the following best describes the purpose of applying evidence-based practice to informatics solutions?
🟢 A. To reduce the cost of technology implementation
🟢 B. To ensure that technology decisions are grounded in research and clinical best practices
🟢 C. To satisfy regulatory requirements for technology adoption
🟢 D. To increase vendor competition for healthcare contracts
🔴🔴 Correct Answer: B
Rationale: Evidence-based practice in informatics involves applying literature reviews, clinical practice guidelines, and emerging trends
to inform technology decisions. The goal is to ensure that informatics solutions are effective, safe, and aligned with current best
evidence rather than solely cost-driven or compliance-focused.
• Q4. A nurse informaticist conducts a literature review on clinical decision support systems before recommending a solution. This
activity demonstrates which professional practice competency?
🟢 A. Self-development strategy
🟢 B. Policy promotion
🟢 C. Evidence-based practice application
🟢 D. Interprofessional collaboration
🔴🔴 Correct Answer: C
Rationale: Applying evidence-based practice of informatics solutions includes conducting literature reviews and evaluations of clinical
practice guidelines. The informaticist's action of performing a literature review directly reflects this competency.
• Q5. Which of the following is a self-development strategy for an informatics nurse seeking career advancement?
🟢 A. Reducing continuing education hours to focus on clinical work
🟢 B. Setting performance goals and evaluating competency development
🟢 C. Avoiding membership in professional organizations
🟢 D. Limiting participation to only clinical nursing activities
🔴🔴 Correct Answer: B
Rationale: Self-development strategies for informatics nurses include performance goal setting, continuing education, competency
development, and engagement with informatics professional organizations. Setting performance goals and evaluating competency
,development is a proactive approach to professional growth.
• Q6. An informatics nurse is mentoring a new graduate nurse interested in the specialty. According to the ANA scope and standards,
which of the following is a key responsibility of mentoring in informatics?
🟢 A. Assigning the mentee to complete all technical support tickets
🟢 B. Delegating all project management tasks to the mentee
🟢 C. Guiding professional development and sharing expertise in informatics practice
🟢 D. Requiring the mentee to work independently without supervision
🔴🔴 Correct Answer: C
Rationale: Mentoring is a general management fundamental in informatics nursing that involves guiding professional development
and sharing expertise. Effective mentoring supports the growth of future informatics nurses through knowledge transfer and
professional guidance.
• Q7. A nurse informaticist is advocating for health equity by analyzing population health data to identify disparities in access to
telehealth services. This activity aligns with which professional practice responsibility?
🟢 A. Budget management
🟢 B. Policy promotion and public advocacy for health equity
🟢 C. System design
🟢 D. Vendor contract negotiation
🔴🔴 Correct Answer: B
Rationale: Policy promotion and public advocacy for health equity includes promoting community-level health equity awareness,
understanding social determinants of health (SDOH), and population health risk stratification. Analyzing data to identify disparities in
telehealth access directly reflects this responsibility.
• Q8. Which of the following demonstrates the application of leadership principles in informatics nursing?
🟢 A. Independently completing all technical programming tasks
🟢 B. Influencing stakeholders to adopt evidence-based technology solutions
🟢 C. Avoiding conflict during system implementation
🟢 D. Focusing exclusively on technical troubleshooting
🔴🔴 Correct Answer: B
Rationale: Leadership in informatics nursing involves influencing stakeholders, guiding change, and promoting adoption of evidence-
based solutions. Effective leadership extends beyond technical tasks to include persuasion, collaboration, and change management.
• Q9. An informatics nurse participates in a professional organization's advocacy efforts to influence health information technology
policy at the state level. This activity represents which competency?
🟢 A. Technical support
🟢 B. Policy promotion
🟢 C. System testing
🟢 D. Data analysis
🔴🔴 Correct Answer: B
Rationale: Policy promotion involves advocating for health equity and influencing policies that affect nursing informatics practice.
Engaging in professional organization advocacy efforts to shape health IT policy exemplifies this competency.
, • Q10. Which of the following is essential for an informatics nurse to demonstrate competency in professional practice?
🟢 A. Knowledge of nursing informatics scope and standards of practice
🟢 B. Ability to write computer code in multiple programming languages
🟢 C. Expertise in hardware repair and maintenance
🟢 D. Proficiency in medical billing and coding
🔴🔴 Correct Answer: A
Rationale: Knowledge of nursing informatics scope and standards of practice is foundational to professional practice in the specialty.
While technical skills are valuable, understanding the professional scope and standards defines the practice of nursing informatics.
• Q11. A nurse informaticist is evaluating the effectiveness of a new clinical workflow after implementing an electronic health record
(EHR) system. Which professional practice activity is being performed?
🟢 A. System design
🟢 B. Evaluation of informatics solutions
🟢 C. Vendor selection
🟢 D. Hardware procurement
🔴🔴 Correct Answer: B
Rationale: Evaluating informatics solutions is a core professional practice competency that involves assessing the effectiveness of
technology implementations. The informaticist is engaged in post-implementation evaluation to determine workflow effectiveness.
• Q12. An informatics nurse promotes the specialty by presenting at a national conference about the role of nursing informatics in
improving patient outcomes. This activity demonstrates which professional practice element?
🟢 A. Budget management
🟢 B. Promoting informatics
🟢 C. System testing
🟢 D. Regulatory compliance
🔴🔴 Correct Answer: B
Rationale: Promoting informatics includes sharing knowledge about the specialty and its contributions to healthcare through
professional presentations and publications. Presenting at a national conference advances the visibility and understanding of nursing
informatics.
I.B: Methodologies and Theories
• Q13. In the Data-Information-Knowledge-Wisdom (DIKW) framework, a nurse uses clinical decision support to recommend an
alternative medication based on patient-specific data and evidence. Which level of the DIKW hierarchy does this represent?
🟢 A. Data
🟢 B. Information
🟢 C. Knowledge
🟢 D. Wisdom
🔴🔴 Correct Answer: D
Rationale: Wisdom represents the application of knowledge to make appropriate clinical decisions in specific contexts. The nurse
applying decision support recommendations based on patient-specific data and evidence demonstrates wisdom—the highest level of
the DIKW hierarchy.
Bank
Table of Contents
Section Content Domain Question Numbers
I Foundations of Practice 1 – 54
I.A Professional Practice 1 – 12
I.B Methodologies and Theories 13 – 27
I.C Rules, Regulations, and Requirements 28 – 42
I.D Interprofessional Collaboration 43 – 54
II System Design Lifecycle 55 – 103
II.A Planning and Analysis 55 – 67
II.B Designing and Building 68 – 80
II.C Testing, Training, and Implementation 81 – 93
Monitoring, Maintaining, Supporting, and
II.D 94 – 103
Evaluating
III Data Management and Healthcare Technology 104 – 150
III.A Data Standards and Terminology 104 – 116
III.B Data Management and Analytics 117 – 129
III.C Healthcare Technology and Clinical Systems 130 – 140
III.D Security, Privacy, and Interoperability 141 – 150
SECTION I: FOUNDATIONS OF PRACTICE (45 Questions)
I.A: Professional Practice
• Q1. The American Nurses Association (ANA) recognizes nursing informatics as a specialty that integrates nursing science with which
of the following foundational sciences?
🟢 A. Computer science and library science
🟢 B. Information science and computer science
🟢 C. Cognitive science and systems science
🟢 D. Data science and engineering
🔴🔴 Correct Answer: B
,Rationale: The ANA defines nursing informatics as the specialty that integrates nursing science with information science and computer
science to manage and communicate data, information, knowledge, and wisdom in nursing practice. This tripartite foundation
distinguishes nursing informatics from other health informatics disciplines.
• Q2. A nurse informaticist is developing a strategic plan for implementing a new clinical documentation system across a multi-
hospital system. Which management function is the informaticist primarily demonstrating?
🟢 A. Budgeting only
🟢 B. Strategic planning
🟢 C. Mentoring
🟢 D. Policy promotion
🔴🔴 Correct Answer: B
Rationale: Strategic planning is a core management fundamental in informatics nursing practice that involves developing long-term
direction and resource allocation for technology initiatives. The scenario describes the informaticist engaged in high-level planning
across the organization, which exemplifies strategic planning rather than the other options.
• Q3. Which of the following best describes the purpose of applying evidence-based practice to informatics solutions?
🟢 A. To reduce the cost of technology implementation
🟢 B. To ensure that technology decisions are grounded in research and clinical best practices
🟢 C. To satisfy regulatory requirements for technology adoption
🟢 D. To increase vendor competition for healthcare contracts
🔴🔴 Correct Answer: B
Rationale: Evidence-based practice in informatics involves applying literature reviews, clinical practice guidelines, and emerging trends
to inform technology decisions. The goal is to ensure that informatics solutions are effective, safe, and aligned with current best
evidence rather than solely cost-driven or compliance-focused.
• Q4. A nurse informaticist conducts a literature review on clinical decision support systems before recommending a solution. This
activity demonstrates which professional practice competency?
🟢 A. Self-development strategy
🟢 B. Policy promotion
🟢 C. Evidence-based practice application
🟢 D. Interprofessional collaboration
🔴🔴 Correct Answer: C
Rationale: Applying evidence-based practice of informatics solutions includes conducting literature reviews and evaluations of clinical
practice guidelines. The informaticist's action of performing a literature review directly reflects this competency.
• Q5. Which of the following is a self-development strategy for an informatics nurse seeking career advancement?
🟢 A. Reducing continuing education hours to focus on clinical work
🟢 B. Setting performance goals and evaluating competency development
🟢 C. Avoiding membership in professional organizations
🟢 D. Limiting participation to only clinical nursing activities
🔴🔴 Correct Answer: B
Rationale: Self-development strategies for informatics nurses include performance goal setting, continuing education, competency
development, and engagement with informatics professional organizations. Setting performance goals and evaluating competency
,development is a proactive approach to professional growth.
• Q6. An informatics nurse is mentoring a new graduate nurse interested in the specialty. According to the ANA scope and standards,
which of the following is a key responsibility of mentoring in informatics?
🟢 A. Assigning the mentee to complete all technical support tickets
🟢 B. Delegating all project management tasks to the mentee
🟢 C. Guiding professional development and sharing expertise in informatics practice
🟢 D. Requiring the mentee to work independently without supervision
🔴🔴 Correct Answer: C
Rationale: Mentoring is a general management fundamental in informatics nursing that involves guiding professional development
and sharing expertise. Effective mentoring supports the growth of future informatics nurses through knowledge transfer and
professional guidance.
• Q7. A nurse informaticist is advocating for health equity by analyzing population health data to identify disparities in access to
telehealth services. This activity aligns with which professional practice responsibility?
🟢 A. Budget management
🟢 B. Policy promotion and public advocacy for health equity
🟢 C. System design
🟢 D. Vendor contract negotiation
🔴🔴 Correct Answer: B
Rationale: Policy promotion and public advocacy for health equity includes promoting community-level health equity awareness,
understanding social determinants of health (SDOH), and population health risk stratification. Analyzing data to identify disparities in
telehealth access directly reflects this responsibility.
• Q8. Which of the following demonstrates the application of leadership principles in informatics nursing?
🟢 A. Independently completing all technical programming tasks
🟢 B. Influencing stakeholders to adopt evidence-based technology solutions
🟢 C. Avoiding conflict during system implementation
🟢 D. Focusing exclusively on technical troubleshooting
🔴🔴 Correct Answer: B
Rationale: Leadership in informatics nursing involves influencing stakeholders, guiding change, and promoting adoption of evidence-
based solutions. Effective leadership extends beyond technical tasks to include persuasion, collaboration, and change management.
• Q9. An informatics nurse participates in a professional organization's advocacy efforts to influence health information technology
policy at the state level. This activity represents which competency?
🟢 A. Technical support
🟢 B. Policy promotion
🟢 C. System testing
🟢 D. Data analysis
🔴🔴 Correct Answer: B
Rationale: Policy promotion involves advocating for health equity and influencing policies that affect nursing informatics practice.
Engaging in professional organization advocacy efforts to shape health IT policy exemplifies this competency.
, • Q10. Which of the following is essential for an informatics nurse to demonstrate competency in professional practice?
🟢 A. Knowledge of nursing informatics scope and standards of practice
🟢 B. Ability to write computer code in multiple programming languages
🟢 C. Expertise in hardware repair and maintenance
🟢 D. Proficiency in medical billing and coding
🔴🔴 Correct Answer: A
Rationale: Knowledge of nursing informatics scope and standards of practice is foundational to professional practice in the specialty.
While technical skills are valuable, understanding the professional scope and standards defines the practice of nursing informatics.
• Q11. A nurse informaticist is evaluating the effectiveness of a new clinical workflow after implementing an electronic health record
(EHR) system. Which professional practice activity is being performed?
🟢 A. System design
🟢 B. Evaluation of informatics solutions
🟢 C. Vendor selection
🟢 D. Hardware procurement
🔴🔴 Correct Answer: B
Rationale: Evaluating informatics solutions is a core professional practice competency that involves assessing the effectiveness of
technology implementations. The informaticist is engaged in post-implementation evaluation to determine workflow effectiveness.
• Q12. An informatics nurse promotes the specialty by presenting at a national conference about the role of nursing informatics in
improving patient outcomes. This activity demonstrates which professional practice element?
🟢 A. Budget management
🟢 B. Promoting informatics
🟢 C. System testing
🟢 D. Regulatory compliance
🔴🔴 Correct Answer: B
Rationale: Promoting informatics includes sharing knowledge about the specialty and its contributions to healthcare through
professional presentations and publications. Presenting at a national conference advances the visibility and understanding of nursing
informatics.
I.B: Methodologies and Theories
• Q13. In the Data-Information-Knowledge-Wisdom (DIKW) framework, a nurse uses clinical decision support to recommend an
alternative medication based on patient-specific data and evidence. Which level of the DIKW hierarchy does this represent?
🟢 A. Data
🟢 B. Information
🟢 C. Knowledge
🟢 D. Wisdom
🔴🔴 Correct Answer: D
Rationale: Wisdom represents the application of knowledge to make appropriate clinical decisions in specific contexts. The nurse
applying decision support recommendations based on patient-specific data and evidence demonstrates wisdom—the highest level of
the DIKW hierarchy.
