NUR 6130 Exam 2 WPU Advanced Practice Nursing III –
(2026/2027) Actual Questions, Verified Answers with
Rationales (Guarantee Pass)
Section 1: Infectious Disease & Dermatology
Q1. A 2-year-old presents with a 4-day fever (Tmax 102°F). Today, the mother
states the fever has resolved, but now the child has a generalized rosy pink
macular rash. What would you suspect is the cause?
• A) Rubella
• B) Roseola
• C) Fifth disease
• D) Scarlet fever
Answer: B) Roseola
Rationale: Roseola (HHV-6) is characterized by several days of high fever followed
by a rash that appears as the fever breaks—classically a trunk-predominant pink
macular exanthem. The "fever first, rash after" pattern distinguishes it from other
viral exanthems .
Q2. The most likely causative organism of bronchiolitis is:
• A) Haemophilus influenzae
• B) Parainfluenza virus
• C) Respiratory syncytial virus
• D) Coxsackievirus
Answer: C) Respiratory syncytial virus
Rationale: RSV is the leading cause of bronchiolitis in infants and young children,
characterized by wheezing, cough, tachypnea, and increased work of breathing.
The infection is seasonal, typically occurring in fall and winter months .
,Q3. Which of the following signs would lead you to include a diagnosis other
than UTI in the differential?
• A) Urinary frequency
• B) Penile discharge
• C) Suprapubic or urethral pain
• D) Incontinence
Answer: B) Penile discharge
Rationale: Penile discharge suggests urethritis or STI rather than simple cystitis,
especially in adolescents. Frequency, dysuria, and suprapubic pain are typical of
UTI. The presence of discharge warrants investigation for sexually transmitted
infections .
Q4. The incidence of epiglottitis has decreased due to which vaccine?
• A) Prevnar
• B) Varicella
• C) HIB
• D) Meningococcal
Answer: C) HIB
Rationale: Haemophilus influenzae type b was historically the most common
cause of pediatric epiglottitis. Routine Hib vaccination has dramatically reduced
its incidence .
Q5. A mother brings her 4-year-old for a well visit during the winter season. She
states that he is immunocompromised. What vaccine would you anticipate the
child not receiving today?
• A) DTaP
, • B) IPV
• C) MMR
• D) Flu vaccine
Answer: C) MMR
Rationale: MMR is a live attenuated vaccine and is contraindicated or used
cautiously in immunocompromised children. Inactivated vaccines like DTaP, IPV,
and inactivated flu vaccine are generally safe in immunocompromised patients .
Q6. All of the following can be used to treat pharyngitis except:
• A) Clindamycin
• B) Erythromycin
• C) Sulfamethoxazole/trimethoprim
• D) Ceftriaxone
Answer: C) Sulfamethoxazole/trimethoprim
Rationale: TMP-SMX does not reliably eradicate Group A strep from the pharynx
and is not recommended for strep pharyngitis. Penicillins, cephalosporins,
macrolides, and clindamycin are preferred agents .
Q7. A 12-year-old is being treated for strep throat. The mother reports that he is
allergic to penicillin and possibly to cefdinir. Which antibiotic is the preferred
drug of choice?
• A) Cephalexin
• B) Doxycycline
• C) Azithromycin
• D) Levofloxacin
Answer: C) Azithromycin
, Rationale: For GAS pharyngitis in a child with true penicillin and cephalosporin
allergy, a macrolide such as azithromycin is an appropriate alternative. Macrolides
are effective against Group A Streptococcus and are safe in penicillin-allergic
patients .
Q8. Which of the following best describes the treatment for roseola?
• A) Acetaminophen or ibuprofen for fever, parental reassurance
• B) Warm compresses for salivary gland swelling
• C) Oral acyclovir, 20mg/kg/dose, four times a day
• D) Bed rest, saline gargles for sore throat
Answer: A) Acetaminophen or ibuprofen for fever, parental reassurance
Rationale: Roseola is a self-limited viral illness; management is supportive with
antipyretics and reassurance once serious etiologies for fever are excluded. No
antiviral therapy is indicated .
Q9. A 16-year-old female presents with symptoms of frequency and burning on
urination with suprapubic tenderness x 3 days. No fever. Urine dipstick is
positive for leukocytes and nitrates. What antibiotic would you anticipate
treating this patient with?
• A) Ciprofloxacin
• B) Nitrofurantoin
• C) Amoxicillin
• D) Doxycycline
Answer: B) Nitrofurantoin
Rationale: For uncomplicated UTI in an adolescent female, nitrofurantoin is a
first-line agent. It concentrates in the urine and is effective against common
uropathogens. The positive nitrates suggest Enterobacteriaceae infection .
(2026/2027) Actual Questions, Verified Answers with
Rationales (Guarantee Pass)
Section 1: Infectious Disease & Dermatology
Q1. A 2-year-old presents with a 4-day fever (Tmax 102°F). Today, the mother
states the fever has resolved, but now the child has a generalized rosy pink
macular rash. What would you suspect is the cause?
• A) Rubella
• B) Roseola
• C) Fifth disease
• D) Scarlet fever
Answer: B) Roseola
Rationale: Roseola (HHV-6) is characterized by several days of high fever followed
by a rash that appears as the fever breaks—classically a trunk-predominant pink
macular exanthem. The "fever first, rash after" pattern distinguishes it from other
viral exanthems .
Q2. The most likely causative organism of bronchiolitis is:
• A) Haemophilus influenzae
• B) Parainfluenza virus
• C) Respiratory syncytial virus
• D) Coxsackievirus
Answer: C) Respiratory syncytial virus
Rationale: RSV is the leading cause of bronchiolitis in infants and young children,
characterized by wheezing, cough, tachypnea, and increased work of breathing.
The infection is seasonal, typically occurring in fall and winter months .
,Q3. Which of the following signs would lead you to include a diagnosis other
than UTI in the differential?
• A) Urinary frequency
• B) Penile discharge
• C) Suprapubic or urethral pain
• D) Incontinence
Answer: B) Penile discharge
Rationale: Penile discharge suggests urethritis or STI rather than simple cystitis,
especially in adolescents. Frequency, dysuria, and suprapubic pain are typical of
UTI. The presence of discharge warrants investigation for sexually transmitted
infections .
Q4. The incidence of epiglottitis has decreased due to which vaccine?
• A) Prevnar
• B) Varicella
• C) HIB
• D) Meningococcal
Answer: C) HIB
Rationale: Haemophilus influenzae type b was historically the most common
cause of pediatric epiglottitis. Routine Hib vaccination has dramatically reduced
its incidence .
Q5. A mother brings her 4-year-old for a well visit during the winter season. She
states that he is immunocompromised. What vaccine would you anticipate the
child not receiving today?
• A) DTaP
, • B) IPV
• C) MMR
• D) Flu vaccine
Answer: C) MMR
Rationale: MMR is a live attenuated vaccine and is contraindicated or used
cautiously in immunocompromised children. Inactivated vaccines like DTaP, IPV,
and inactivated flu vaccine are generally safe in immunocompromised patients .
Q6. All of the following can be used to treat pharyngitis except:
• A) Clindamycin
• B) Erythromycin
• C) Sulfamethoxazole/trimethoprim
• D) Ceftriaxone
Answer: C) Sulfamethoxazole/trimethoprim
Rationale: TMP-SMX does not reliably eradicate Group A strep from the pharynx
and is not recommended for strep pharyngitis. Penicillins, cephalosporins,
macrolides, and clindamycin are preferred agents .
Q7. A 12-year-old is being treated for strep throat. The mother reports that he is
allergic to penicillin and possibly to cefdinir. Which antibiotic is the preferred
drug of choice?
• A) Cephalexin
• B) Doxycycline
• C) Azithromycin
• D) Levofloxacin
Answer: C) Azithromycin
, Rationale: For GAS pharyngitis in a child with true penicillin and cephalosporin
allergy, a macrolide such as azithromycin is an appropriate alternative. Macrolides
are effective against Group A Streptococcus and are safe in penicillin-allergic
patients .
Q8. Which of the following best describes the treatment for roseola?
• A) Acetaminophen or ibuprofen for fever, parental reassurance
• B) Warm compresses for salivary gland swelling
• C) Oral acyclovir, 20mg/kg/dose, four times a day
• D) Bed rest, saline gargles for sore throat
Answer: A) Acetaminophen or ibuprofen for fever, parental reassurance
Rationale: Roseola is a self-limited viral illness; management is supportive with
antipyretics and reassurance once serious etiologies for fever are excluded. No
antiviral therapy is indicated .
Q9. A 16-year-old female presents with symptoms of frequency and burning on
urination with suprapubic tenderness x 3 days. No fever. Urine dipstick is
positive for leukocytes and nitrates. What antibiotic would you anticipate
treating this patient with?
• A) Ciprofloxacin
• B) Nitrofurantoin
• C) Amoxicillin
• D) Doxycycline
Answer: B) Nitrofurantoin
Rationale: For uncomplicated UTI in an adolescent female, nitrofurantoin is a
first-line agent. It concentrates in the urine and is effective against common
uropathogens. The positive nitrates suggest Enterobacteriaceae infection .
