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BIOM 3090 CNS PHARMACOLOGY QUESTIONS AND CORRECT ANSWERS

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BIOM 3090 CNS PHARMACOLOGY QUESTIONS AND CORRECT ANSWERS

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selective inhibition of MAO-B is generally ________.


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well tolerated




How is PD diagnosed?


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based on medical history and neurological examination and symptoms




What is Schizophrenia?

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literally meaning "shattered mind", it is the breakdown of thought processes
and lack of typical emotions




What are anti-psychotic drugs?


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also known as neuroleptics, decrease dopamine synaptic activity in the
limbic pathway




Symptoms of PD?


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- bradykinesia
- rigidity
- impaired balance
- tremors when limbs at rest
- more advanced; impaired movement & speech




low dopamine in the _______ system is linked to _______.


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cortical; negative symptoms

, What is the glutamate hypothesis?


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hypothetical pathway involving imbalance in glutameric transmission linked
to varying systemic DA levels




selegiline


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(same as pargyline in documentary)




direct pathway signals


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putamen to GPi to thalamus and cortex




when released by interneurons, ACh (neuromodulators) is associated with _______.


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motor control

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