AND CORRECT ANSWERS
Pharmacokinetics - CORRECT ANSWER the study of drug movement throughout the body
4 steps pharmokinetics - CORRECT ANSWER absorption, distribution, metabolism, excretion
Absorption - CORRECT ANSWER drug movement from the site of injection into the blood
Increased lipid solubility leads to ____ absorption - CORRECT ANSWER increased
IV absorption - CORRECT ANSWER immediate
IM / subcutaneous absorption - CORRECT ANSWER rapid if H2O soluble
Poor if not
Oral absorption - CORRECT ANSWER slow, variable
Enteral - CORRECT ANSWER within GI tract - oral
Parenteral - CORRECT ANSWER outside GI tract - IV, IM, subcutaneous
Distribution - CORRECT ANSWER drug travels from blood into tissue and cells
Increased tissue blood flow leads to ___ distribution - CORRECT ANSWER increased
Protein bound drugs - CORRECT ANSWER can't cross capillary walls
Free drugs - CORRECT ANSWER not bound to protein, can cross capillary walls