COMSAE Phase 1 Form 113 exam Questions And Correct Answers (Verified Answers) Plus
Rationales 2026 Q&A Complete Practice Test Bank Exam-Style 300 Questions with Verified
Answers & Detailed Rationales All Core Domains Covered | A+ Graded
Table of Contents
| Section | Topic | Questions |
|---------|-------|-----------|
| 1 | Osteopathic Principles & OMM | 1–40 |
| 2 | Anatomy & Embryology | 41–65 |
| 3 | Physiology & Pathophysiology | 66–90 |
| 4 | Biochemistry & Molecular Biology | 91–110 |
| 5 | Microbiology & Immunology | 111–135 |
| 6 | Pharmacology & Toxicology | 136–160 |
| 7 | Pathology | 161–185 |
| 8 | Cardiovascular System | 186–205 |
| 9 | Respiratory System | 206–220 |
| 10 | Renal & Electrolytes | 221–235 |
| 11 | Gastrointestinal System | 236–250 |
| 12 | Endocrine & Reproductive | 251–265 |
| 13 | Neurology & Neuroanatomy | 266–280 |
| 14 | Behavioral Science, Ethics & Biostatistics | 281–295 |
| 15 | Integrated Clinical Reasoning | 296–300 |
---
Exam Overview
,Exam: COMSAE Phase 1 Form 113 Practice Examination
Total Questions: 300
Question Type: Single-best-answer multiple choice
Format: Clinical vignette-style questions
Content Focus: Foundational biomedical sciences integrated with osteopathic principles and
clinical reasoning
Content Areas Covered:
- Osteopathic Principles, OMM, & Somatic Dysfunction (TART, viscerosomatic, Fryette's Laws)
- Anatomy, Embryology & Histology
- Physiology & Pathophysiology
- Biochemistry & Molecular Biology
- Microbiology & Immunology
- Pharmacology & Toxicology
- Pathology
- Cardiovascular, Respiratory, Renal, GI, Endocrine, Reproductive, Neurologic Systems
- Behavioral Science, Psychiatry, Ethics & Biostatistics
- Integrated Clinical Reasoning
How to Use This Guide:
1. Read each clinical vignette carefully.
2. Select your answer before viewing the correct response.
3. Study the bolded answer and detailed rationale.
4. Note the key pathophysiological mechanism tested.
,---
SECTION 1: OSTEOPATHIC PRINCIPLES & OMM (Questions 1–40)
Question 1
A patient presents with tissue texture changes, asymmetry, restriction of motion, and
tenderness at T5–T7. These findings are collectively known as which osteopathic concept?
A) Fryette mechanics
B) TART findings
C) Chapman reflexes
D) Facilitation syndrome
Answer: B) TART findings
Rationale: TART = Tissue texture changes, Asymmetry, Restriction of motion, Tenderness — the
four diagnostic criteria for somatic dysfunction.
---
Question 2
A 45-year-old woman presents with epigastric burning and bloating after meals for several
months. On osteopathic structural exam, you find tenderness and increased tissue texture at
the right T6–T8 paraspinal region. Which viscerosomatic reflex best explains this finding?
A) Gallbladder
B) Stomach
C) Pancreas
D) Liver
, Answer: B) Stomach
Rationale: Viscerosomatic reflexes map spinal cord levels to organs. The stomach corresponds
to T6–T9, with a predilection for the right side. Gallbladder (T7–T9) often presents on the right,
but epigastric symptoms and T6–T8 tenderness more specifically point to the stomach. Pancreas
(T6–T10) can be similar, but the history of epigastric burning is classic for gastritis/PUD.
---
Question 3
A 24-year-old male has acute low back pain after lifting. Prone exam shows right ASIS superior
and right PSIS inferior. Standing flexion test positive on right. What is the diagnosis?
A) Right anterior innominate rotation
B) Right posterior innominate rotation
C) Left superior innominate shear
D) Right superior innominate shear
Answer: B) Right posterior innominate rotation
Rationale: Positive standing flexion test localizes to right. Posterior rotation has ASIS superior
and PSIS inferior on the affected side.
---
Question 4
A 28-year-old runner presents with chronic low back pain. On seated flexion test, the right PSIS
moves superiorly earlier and more than the left. In the prone position, the right ILA is more
posterior than the left, and both ILAs move equally with spring test. What is the most likely
sacral diagnosis?
A) Left on left sacral torsion
Rationales 2026 Q&A Complete Practice Test Bank Exam-Style 300 Questions with Verified
Answers & Detailed Rationales All Core Domains Covered | A+ Graded
Table of Contents
| Section | Topic | Questions |
|---------|-------|-----------|
| 1 | Osteopathic Principles & OMM | 1–40 |
| 2 | Anatomy & Embryology | 41–65 |
| 3 | Physiology & Pathophysiology | 66–90 |
| 4 | Biochemistry & Molecular Biology | 91–110 |
| 5 | Microbiology & Immunology | 111–135 |
| 6 | Pharmacology & Toxicology | 136–160 |
| 7 | Pathology | 161–185 |
| 8 | Cardiovascular System | 186–205 |
| 9 | Respiratory System | 206–220 |
| 10 | Renal & Electrolytes | 221–235 |
| 11 | Gastrointestinal System | 236–250 |
| 12 | Endocrine & Reproductive | 251–265 |
| 13 | Neurology & Neuroanatomy | 266–280 |
| 14 | Behavioral Science, Ethics & Biostatistics | 281–295 |
| 15 | Integrated Clinical Reasoning | 296–300 |
---
Exam Overview
,Exam: COMSAE Phase 1 Form 113 Practice Examination
Total Questions: 300
Question Type: Single-best-answer multiple choice
Format: Clinical vignette-style questions
Content Focus: Foundational biomedical sciences integrated with osteopathic principles and
clinical reasoning
Content Areas Covered:
- Osteopathic Principles, OMM, & Somatic Dysfunction (TART, viscerosomatic, Fryette's Laws)
- Anatomy, Embryology & Histology
- Physiology & Pathophysiology
- Biochemistry & Molecular Biology
- Microbiology & Immunology
- Pharmacology & Toxicology
- Pathology
- Cardiovascular, Respiratory, Renal, GI, Endocrine, Reproductive, Neurologic Systems
- Behavioral Science, Psychiatry, Ethics & Biostatistics
- Integrated Clinical Reasoning
How to Use This Guide:
1. Read each clinical vignette carefully.
2. Select your answer before viewing the correct response.
3. Study the bolded answer and detailed rationale.
4. Note the key pathophysiological mechanism tested.
,---
SECTION 1: OSTEOPATHIC PRINCIPLES & OMM (Questions 1–40)
Question 1
A patient presents with tissue texture changes, asymmetry, restriction of motion, and
tenderness at T5–T7. These findings are collectively known as which osteopathic concept?
A) Fryette mechanics
B) TART findings
C) Chapman reflexes
D) Facilitation syndrome
Answer: B) TART findings
Rationale: TART = Tissue texture changes, Asymmetry, Restriction of motion, Tenderness — the
four diagnostic criteria for somatic dysfunction.
---
Question 2
A 45-year-old woman presents with epigastric burning and bloating after meals for several
months. On osteopathic structural exam, you find tenderness and increased tissue texture at
the right T6–T8 paraspinal region. Which viscerosomatic reflex best explains this finding?
A) Gallbladder
B) Stomach
C) Pancreas
D) Liver
, Answer: B) Stomach
Rationale: Viscerosomatic reflexes map spinal cord levels to organs. The stomach corresponds
to T6–T9, with a predilection for the right side. Gallbladder (T7–T9) often presents on the right,
but epigastric symptoms and T6–T8 tenderness more specifically point to the stomach. Pancreas
(T6–T10) can be similar, but the history of epigastric burning is classic for gastritis/PUD.
---
Question 3
A 24-year-old male has acute low back pain after lifting. Prone exam shows right ASIS superior
and right PSIS inferior. Standing flexion test positive on right. What is the diagnosis?
A) Right anterior innominate rotation
B) Right posterior innominate rotation
C) Left superior innominate shear
D) Right superior innominate shear
Answer: B) Right posterior innominate rotation
Rationale: Positive standing flexion test localizes to right. Posterior rotation has ASIS superior
and PSIS inferior on the affected side.
---
Question 4
A 28-year-old runner presents with chronic low back pain. On seated flexion test, the right PSIS
moves superiorly earlier and more than the left. In the prone position, the right ILA is more
posterior than the left, and both ILAs move equally with spring test. What is the most likely
sacral diagnosis?
A) Left on left sacral torsion
