ATI RN Fundamentals Exam — 200 Practice Questions with Verified Answers & Rationales (2026
Q&A)
Table of Contents
| Topic | Questions |
|-------|-----------|
| Topic 1: Safety & Infection Control | 1–30 |
| Topic 2: Delegation & Assignment Management | 31–50 |
| Topic 3: Medication Administration & Calculations | 51–70 |
| Topic 4: Therapeutic Communication & Client Education | 71–90 |
| Topic 5: Nutrition, Mobility & Elimination | 91–110 |
| Topic 6: Wound Care & Skin Integrity | 111–125 |
| Topic 7: Legal & Ethical Issues | 126–140 |
| Topic 8: Oxygenation & Respiratory Care | 141–160 |
| Topic 9: Assessment & Vital Signs | 161–180 |
| Topic 10: End-of-Life Care, Postmortem Care & Pain Management | 181–200 |
Topic 1: Safety & Infection Control (Questions 1–30)
1. A nurse is preparing to perform hand hygiene. Which action is the most effective way to
prevent the spread of healthcare-associated infections?
A) Using hot water for handwashing
B) Applying an alcohol-based hand sanitizer and rubbing until dry
,C) Washing hands with soap and water for 5 seconds
D) Wearing gloves for all client interactions
Answer: B
Rationale: Vigorous friction with an alcohol-based hand sanitizer for at least 15 seconds is the
most effective method for routine hand hygiene to prevent the spread of healthcare-associated
infections.
---
2. A nurse is caring for a client on contact precautions. Which of the following actions should
the nurse take?
A) Place the client in a negative pressure room
B) Wear an N95 respirator when entering the room
C) Wear a gown and gloves when providing care
D) Keep the door closed at all times
Answer: C
Rationale: Contact precautions require gown and gloves for all staff entering the room. Negative
pressure and N95 respirators are for airborne precautions.
---
3. A charge nurse is discussing the responsibility of nurses caring for clients who have a
Clostridium difficile infection. Which of the following information should the nurse include in
the teaching?
,A) Assign the client to a room with a negative air-flow system
B) Use alcohol-based hand sanitizer after client contact
C) Wear a gown and gloves when entering the client's room
D) Keep the client's door closed at all times
Answer: C
Rationale: C. difficile requires contact precautions, which include gown and gloves. Alcohol-
based hand sanitizer is not effective against C. difficile spores—soap and water must be used.
---
4. A nurse is caring for a client with tuberculosis. Which personal protective equipment should
the nurse use?
A) Surgical mask
B) N95 respirator
C) Gown and gloves only
D) Face shield
Answer: B
Rationale: Tuberculosis requires airborne precautions, which include wearing an N95 respirator.
---
5. A nurse finds a patient's room filled with smoke. What is the priority action?
A) Extinguish the fire
, B) Rescue the patient
C) Sound the alarm
D) Close the door
Answer: B
Rationale: The RACE acronym stands for Rescue, Alarm, Contain, and Extinguish. Rescue is the
first priority.
---
6. Which type of precautions should a nurse initiate for a client diagnosed with measles?
A) Contact precautions
B) Droplet precautions
C) Airborne precautions
D) Standard precautions only
Answer: C
Rationale: Measles requires airborne precautions due to transmission via small particles that
remain suspended in the air.
---
7. A nurse is planning care for a group of clients. Which task should the nurse delegate to an
assistive personnel (AP)?
A) Changing the dressing for a client who has a stage 3 pressure injury
Q&A)
Table of Contents
| Topic | Questions |
|-------|-----------|
| Topic 1: Safety & Infection Control | 1–30 |
| Topic 2: Delegation & Assignment Management | 31–50 |
| Topic 3: Medication Administration & Calculations | 51–70 |
| Topic 4: Therapeutic Communication & Client Education | 71–90 |
| Topic 5: Nutrition, Mobility & Elimination | 91–110 |
| Topic 6: Wound Care & Skin Integrity | 111–125 |
| Topic 7: Legal & Ethical Issues | 126–140 |
| Topic 8: Oxygenation & Respiratory Care | 141–160 |
| Topic 9: Assessment & Vital Signs | 161–180 |
| Topic 10: End-of-Life Care, Postmortem Care & Pain Management | 181–200 |
Topic 1: Safety & Infection Control (Questions 1–30)
1. A nurse is preparing to perform hand hygiene. Which action is the most effective way to
prevent the spread of healthcare-associated infections?
A) Using hot water for handwashing
B) Applying an alcohol-based hand sanitizer and rubbing until dry
,C) Washing hands with soap and water for 5 seconds
D) Wearing gloves for all client interactions
Answer: B
Rationale: Vigorous friction with an alcohol-based hand sanitizer for at least 15 seconds is the
most effective method for routine hand hygiene to prevent the spread of healthcare-associated
infections.
---
2. A nurse is caring for a client on contact precautions. Which of the following actions should
the nurse take?
A) Place the client in a negative pressure room
B) Wear an N95 respirator when entering the room
C) Wear a gown and gloves when providing care
D) Keep the door closed at all times
Answer: C
Rationale: Contact precautions require gown and gloves for all staff entering the room. Negative
pressure and N95 respirators are for airborne precautions.
---
3. A charge nurse is discussing the responsibility of nurses caring for clients who have a
Clostridium difficile infection. Which of the following information should the nurse include in
the teaching?
,A) Assign the client to a room with a negative air-flow system
B) Use alcohol-based hand sanitizer after client contact
C) Wear a gown and gloves when entering the client's room
D) Keep the client's door closed at all times
Answer: C
Rationale: C. difficile requires contact precautions, which include gown and gloves. Alcohol-
based hand sanitizer is not effective against C. difficile spores—soap and water must be used.
---
4. A nurse is caring for a client with tuberculosis. Which personal protective equipment should
the nurse use?
A) Surgical mask
B) N95 respirator
C) Gown and gloves only
D) Face shield
Answer: B
Rationale: Tuberculosis requires airborne precautions, which include wearing an N95 respirator.
---
5. A nurse finds a patient's room filled with smoke. What is the priority action?
A) Extinguish the fire
, B) Rescue the patient
C) Sound the alarm
D) Close the door
Answer: B
Rationale: The RACE acronym stands for Rescue, Alarm, Contain, and Extinguish. Rescue is the
first priority.
---
6. Which type of precautions should a nurse initiate for a client diagnosed with measles?
A) Contact precautions
B) Droplet precautions
C) Airborne precautions
D) Standard precautions only
Answer: C
Rationale: Measles requires airborne precautions due to transmission via small particles that
remain suspended in the air.
---
7. A nurse is planning care for a group of clients. Which task should the nurse delegate to an
assistive personnel (AP)?
A) Changing the dressing for a client who has a stage 3 pressure injury
