Page 1 of 141
N580 MIDTERM EXAM*** (COMPREHENSIVE
ADVANCED NURSING COURSE STUDY GUIDE)
QUESTIONS AND ANSWERS | VERIFIED AND
WELL DETAILED ANSWERS |DOWNLOAD AND
PASS | LATEST EXAM UPDATE 2026/2027
Nurses achieve personal growth through and expand
clinical decision-making skills through...
❖Development of clinical questions
❖Literature reviews
❖Evaluation of evidence in literature
❖Application of "best available evidence" in your
practice
Nurses on the cutting edge
❖Promote improvement in patient outcomes
❖Accomplish this through: research, ebp, and qi
,Page 2 of 141
Is the "conclusion" justified? Is the "conclusion"
warranted?
❖You have a cold (cough, runny nose, fever, watery
eyes, aches and pains)
❖I give you the pill and you take it
❖You get better, and the cold goes away
❖You conclude the pill is effective
❖If you don't get better and the cold doesn't go away,
you conclude the pill is ineffective
Why bogus therapies often seem to work
❖The disease may have run its natural course (cold)
❖Many diseases are cyclical (ms has relpases separated
by long periods of relatively normal health)
❖Placebo effect may be responsible
❖Original diagnosis or prognosis may have been
incorrect
,Page 3 of 141
❖Temporary mood improvement can be confused with
a cure
❖Psychological needs can distort what people perceive:
if i've paid money, visited the doctor, etc. Then i have
to get better
Experimental designs for clinical trials (3 critical elements)
❖True experimental designs differ from qualitative or
non-experimental designs: control, manipulation,
randomization
❖A research study using a true experimental design is
commonly called a rct--subjects are randomly
assigned to control group or intervention group, an
intervention or treatment is administered, changes
between groups are assessed statistically
Control populations
, Page 4 of 141
❖Rationale: all true experimental clinical studies
implicitly or explicitly evaluate the intervention (i.e.,
study drug or treatment) against a comparison
(control) treatment
❖Having a control group increase internal validity and
decreases bias in study so you can be sure that if
experimental group had a statistically significant
change on dependent variable than control group,
that the independent variable was the cause of the
change
❖Types of controls:
❖Placebo
❖Dose-comparison
❖Standard of care
❖Historical
Placebo
❖Concurrent, second group that is treated identically,
but receives a placebo rather than the active drug
N580 MIDTERM EXAM*** (COMPREHENSIVE
ADVANCED NURSING COURSE STUDY GUIDE)
QUESTIONS AND ANSWERS | VERIFIED AND
WELL DETAILED ANSWERS |DOWNLOAD AND
PASS | LATEST EXAM UPDATE 2026/2027
Nurses achieve personal growth through and expand
clinical decision-making skills through...
❖Development of clinical questions
❖Literature reviews
❖Evaluation of evidence in literature
❖Application of "best available evidence" in your
practice
Nurses on the cutting edge
❖Promote improvement in patient outcomes
❖Accomplish this through: research, ebp, and qi
,Page 2 of 141
Is the "conclusion" justified? Is the "conclusion"
warranted?
❖You have a cold (cough, runny nose, fever, watery
eyes, aches and pains)
❖I give you the pill and you take it
❖You get better, and the cold goes away
❖You conclude the pill is effective
❖If you don't get better and the cold doesn't go away,
you conclude the pill is ineffective
Why bogus therapies often seem to work
❖The disease may have run its natural course (cold)
❖Many diseases are cyclical (ms has relpases separated
by long periods of relatively normal health)
❖Placebo effect may be responsible
❖Original diagnosis or prognosis may have been
incorrect
,Page 3 of 141
❖Temporary mood improvement can be confused with
a cure
❖Psychological needs can distort what people perceive:
if i've paid money, visited the doctor, etc. Then i have
to get better
Experimental designs for clinical trials (3 critical elements)
❖True experimental designs differ from qualitative or
non-experimental designs: control, manipulation,
randomization
❖A research study using a true experimental design is
commonly called a rct--subjects are randomly
assigned to control group or intervention group, an
intervention or treatment is administered, changes
between groups are assessed statistically
Control populations
, Page 4 of 141
❖Rationale: all true experimental clinical studies
implicitly or explicitly evaluate the intervention (i.e.,
study drug or treatment) against a comparison
(control) treatment
❖Having a control group increase internal validity and
decreases bias in study so you can be sure that if
experimental group had a statistically significant
change on dependent variable than control group,
that the independent variable was the cause of the
change
❖Types of controls:
❖Placebo
❖Dose-comparison
❖Standard of care
❖Historical
Placebo
❖Concurrent, second group that is treated identically,
but receives a placebo rather than the active drug
