lOMoAR cPSD| 67691079
NR507 Practice Questions Hypersensitivity Reactions
1. Which immunoglobulin is central to Type I
hypersensitivity?
A) IgG
B) IgM
C) IgA
D) IgE
✅ Answer: D
Rationale: Type I reactions involve IgE binding to mast
cells and basophils, causing histamine release.
2. What clinical presentation is most associated with Type
I hypersensitivity?
, lOMoAR cPSD| 67691079
A) Hematuria
B) Rash 48 hours after contact
C) Anaphylaxis
D) Hyperthyroidism
✅ Answer: C
Rationale: Type I reactions cause immediate symptoms
like anaphylaxis due to mast cell degranulation.
3. Which mediator causes bronchoconstriction in allergic
asthma? A) Histamine
B) Leukotrienes
C) DopamineD) TSH
, lOMoAR cPSD| 67691079
✅ Answer: B
Rationale: Leukotrienes are responsible for
bronchoconstriction in Type I hypersensitivity.
4. Which diagnostic test confirms autoimmune hemolytic
anemia?
A) ANA
B) Direct Coombs Test
C) RAST
D) ESR
NR507 Practice Questions Hypersensitivity Reactions
1. Which immunoglobulin is central to Type I
hypersensitivity?
A) IgG
B) IgM
C) IgA
D) IgE
✅ Answer: D
Rationale: Type I reactions involve IgE binding to mast
cells and basophils, causing histamine release.
2. What clinical presentation is most associated with Type
I hypersensitivity?
, lOMoAR cPSD| 67691079
A) Hematuria
B) Rash 48 hours after contact
C) Anaphylaxis
D) Hyperthyroidism
✅ Answer: C
Rationale: Type I reactions cause immediate symptoms
like anaphylaxis due to mast cell degranulation.
3. Which mediator causes bronchoconstriction in allergic
asthma? A) Histamine
B) Leukotrienes
C) DopamineD) TSH
, lOMoAR cPSD| 67691079
✅ Answer: B
Rationale: Leukotrienes are responsible for
bronchoconstriction in Type I hypersensitivity.
4. Which diagnostic test confirms autoimmune hemolytic
anemia?
A) ANA
B) Direct Coombs Test
C) RAST
D) ESR
