NEWEST 2026 GUIDELINES |COMPREHENSIVE EXAM BANK 300
ACCURATE QUESTIONS WITH DETAILED RATIONALES
100% VERIFIED | GRADED A+
Domains And Session Breakdown:
Session 1: General Diagnosis, Neuromusculoskeletal Diagnosis, Diagnostic Imaging
Session 2: Principles Of Chiropractic, Chiropractic Practice, Associated Clinical Sciences
Table Of Contents
Domain 1: General Diagnosis (Questions 1-50)
Domain 2: Neuromusculoskeletal Diagnosis (Questions 51-100)
Domain 3: Diagnostic Imaging (Questions 101-150)
Domain 4: Principles Of Chiropractic (Questions 151-200)
Domain 5: Chiropractic Practice (Questions 201-250)
Domain 6: Associated Clinical Sciences (Questions 251-300)
DOMAIN 1: GENERAL DIAGNOSIS (Questions 1-50)
QUESTION 1
A 45-year-old male presents with acute onset of severe right lower quadrant
abdominal
pain, nausea, vomiting, and fever of 101.5°F. On examination, there is rebound
tenderness at McBurney's point. Which of the following is the most likely
diagnosis?
A. Acute cholecystitis
B. Acute appendicitis
C. Renal colic
D. Diverticulitis
E. Peptic ulcer disease
ANSWER: B
RATIONALE: Acute appendicitis typically presents with periumbilical pain that
migrates to the right lower quadrant (RLQ), associated with nausea, vomiting,
anorexia, and fever. McBurney's point tenderness (located two-thirds of the way
from the umbilicus to the anterior superior iliac spine) is a classic finding.
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,Rebound tenderness and guarding indicate peritoneal irritation. Acute
cholecystitis
presents with right upper quadrant pain, often after a fatty meal. Renal colic
presents with flank pain radiating to the groin, often with hematuria. Diverticulitis
presents with left lower quadrant pain, fever, and changes in bowel habits.
Peptic ulcer disease presents with epigastric pain, often relieved by food or
antacids.
QUESTION 2
A patient presents with chest pain described as a sharp, stabbing sensation that
worsens with deep inspiration and improves when leaning forward. An ECG shows
diffuse ST-segment elevation. Which of the following is the most likely diagnosis?
A. Acute myocardial infarction
B. Pulmonary embolism
C. Pericarditis
D. Aortic dissection
E. Costochondritis
ANSWER: C
RATIONALE: Acute pericarditis typically presents with sharp, pleuritic chest pain
that worsens with inspiration and improves with sitting up and leaning forward.
Diffuse ST-segment elevation on ECG is characteristic. A pericardial friction rub
may be audible on auscultation. Acute myocardial infarction presents with
crushing
substernal pain and localized ST elevation. Pulmonary embolism presents with
sudden
dyspnea, tachycardia, and pleuritic chest pain. Aortic dissection presents with
severe tearing pain radiating to the back. Costochondritis presents with localized
chest wall tenderness without ECG changes.
QUESTION 3
A 55-year-old female presents with fatigue, weight gain, cold intolerance,
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,constipation, and dry skin. Laboratory findings reveal elevated TSH and low free
T4.
Which of the following is the most appropriate diagnosis?
A. Hyperthyroidism
B. Hypothyroidism
C. Cushing's syndrome
D. Addison's disease
E. Diabetes mellitus
ANSWER: B
RATIONALE: Hypothyroidism presents with fatigue, weight gain, cold intolerance,
constipation, dry skin, bradycardia, and delayed reflexes. Laboratory findings
show
elevated TSH (primary hypothyroidism) with low free T4. Hyperthyroidism
presents
with weight loss, heat intolerance, tachycardia, and tremor. Cushing's syndrome
presents with weight gain, moon facies, buffalo hump, and hypertension.
Addison's
disease presents with hyperpigmentation, hypotension, and fatigue. Diabetes
mellitus
presents with polyuria, polydipsia, and polyphagia.
QUESTION 4
A 30-year-old female presents with episodes of wheezing, shortness of breath,
and
chest tightness that occur at night and upon exposure to cold air. These episodes
are partially relieved by a bronchodilator. Which of the following is the most
likely diagnosis?
A. Chronic obstructive pulmonary disease (COPD)
B. Asthma
C. Congestive heart failure
D. Pulmonary embolism
E. Pneumonia
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, ANSWER: B
RATIONALE: Asthma is characterized by episodic wheezing, dyspnea, chest
tightness,
and cough, often worse at night or in the early morning. Triggers include cold air,
exercise, allergens, and respiratory infections. Symptoms are reversible with
bronchodilators. COPD is more common in older patients with a significant
smoking
history and presents with progressive, irreversible airflow limitation. Congestive
heart failure presents with orthopnea, paroxysmal nocturnal dyspnea, and
peripheral
edema. Pulmonary embolism presents with sudden onset of dyspnea and pleuritic
chest pain. Pneumonia presents with fever, productive cough, and crackles on
auscultation.
QUESTION 5
A 65-year-old male with a history of hypertension and diabetes presents with
sudden onset of severe headache, nausea, vomiting, and photophobia. On
examination,
he has nuchal rigidity. Which of the following is the most appropriate initial
diagnostic test?
A. CT scan of the head
B. Lumbar puncture
C. MRI of the brain
D. Carotid ultrasound
E. EEG
ANSWER: A
RATIONALE: The patient's presentation is concerning for subarachnoid
hemorrhage
(SAH) or meningitis. CT of the head without contrast is the initial imaging study
of choice to evaluate for SAH, which appears as hyperdensity in the subarachnoid
space. If CT is negative but clinical suspicion remains high, a lumbar puncture
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