NSG 3600 EXAM 2 PRACTICE EXAM – QUESTIONS AND ANSWERS | EXAM
TESTBANK WITH VERIFIED AND WELL DETAILED ANSWERS | PLUS RATIONALES
| DOWNLOAD AND PASS | LATEST EXAM UPDATE 2026/2027
Core Domains:
Pharmacology and Pharmacokinetics
Fluid and Electrolyte Balance
Acute and Chronic Cardiovascular Disorders
Respiratory Physiology and Pathophysiology
Neurological Assessment and Disorders
Endocrine System and Metabolism
Gastrointestinal and Hepatic Function
Renal and Urinary System Disorders
Evidence-Based Practice and Clinical Decision-Making
Legal, Ethical, and Professional Nursing Standards
Introduction
This comprehensive practice examination is designed to rigorously assess your
knowledge and clinical reasoning skills as you prepare for NSG 3600 Exam 2. It
covers a broad spectrum of essential nursing concepts, integrating foundational
theory with applied professional knowledge. The questions are presented in a
multiple-choice and scenario-based format to test not only recall but also your
capacity for critical thinking, clinical judgment, and real-world application. This
resource emphasizes evidence-based practice, patient safety, and the ethical and
legal frameworks that guide professional nursing. It is intended to identify
knowledge gaps, reinforce key concepts, and build confidence for the actual
examination.
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SECTION ONE: QUESTIONS 1–50
1. A patient is prescribed a medication that is a weak acid. Which of the
following conditions would most likely increase the rate of its absorption in the
gastrointestinal tract?
A. Administration with a high-fat meal
B. A higher pH in the stomach due to antacid use
C. A lower pH in the stomach due to gastric acid hypersecretion
D. The presence of food that slows gastric emptying
🟢 Correct Answer: C. A lower pH in the stomach due to gastric acid
hypersecretion
🔴 Explanation: Weak acids are predominantly non-ionized in acidic
environments, which is the form that readily crosses lipid membranes. A lower pH
(more acidic) facilitates this non-ionized state, thereby increasing absorption.
Antacids (higher pH) would decrease absorption. A high-fat meal and slowed
gastric emptying generally delay absorption.
2. A nurse is preparing to administer a drug that has a high first-pass effect.
Which route of administration should the nurse question to ensure therapeutic
effectiveness?
A. Sublingual
B. Oral
C. Intravenous
D. Transdermal
🟢 Correct Answer: B. Oral
,🔴 Explanation: The first-pass effect refers to the significant metabolism of a drug
by the liver before it reaches systemic circulation. Drugs administered orally are
absorbed from the GI tract and directly transported to the liver via the portal vein,
potentially reducing their bioavailability. Sublingual, intravenous, and transdermal
routes bypass this initial hepatic metabolism.
3. A patient in the intensive care unit is receiving intravenous furosemide for
pulmonary edema. Which of the following laboratory values should the nurse
monitor most closely during therapy?
A. Serum sodium
B. Serum potassium
C. Serum calcium
D. Serum albumin
🟢 Correct Answer: B. Serum potassium
🔴 Explanation: Furosemide is a loop diuretic that inhibits the reabsorption of
sodium, potassium, and chloride in the ascending loop of Henle. This results in a
significant loss of potassium, and therefore, hypokalemia is the most common
and clinically significant electrolyte imbalance associated with its use. Monitoring
serum potassium is a critical safety intervention.
4. A client with chronic hypertension is prescribed a beta-blocker. The nurse is
providing discharge instructions. Which statement by the client indicates a
need for further teaching?
A. "I will take my pulse daily before taking the medication."
B. "I must not stop this medication abruptly without my doctor's advice."
C. "I can take this medication with my morning orange juice."
D. "I should avoid over-the-counter cold remedies without checking with my
pharmacist."
, 🟢 Correct Answer: C. "I can take this medication with my morning orange juice."
🔴 Explanation: Grapefruit juice, not orange juice, is known to inhibit the CYP3A4
enzyme in the liver and intestinal wall, which is responsible for metabolizing many
beta-blockers. This can lead to increased drug levels and toxicity. The other
statements reflect correct understanding regarding self-monitoring, the risk of
rebound hypertension with abrupt cessation, and the need to avoid
sympathomimetics in OTC cold remedies.
5. A nurse is assessing a patient who is 24 hours post-operative following a
total hip arthroplasty. The patient's vital signs are: BP 110/70 mmHg, HR 92
bpm, RR 18/min, SpO2 94% on room air. The patient reports sudden onset of
chest pain and shortness of breath. What is the nurse's priority action?
A. Reassure the patient and encourage deep breathing exercises.
B. Administer oxygen via a non-rebreather mask.
C. Assess the patient for calf tenderness and swelling.
D. Notify the healthcare provider of the patient's symptoms.
🟢 Correct Answer: B. Administer oxygen via a non-rebreather mask.
🔴 Explanation: The patient's presentation is highly suspicious for a pulmonary
embolism (PE), a life-threatening complication. The immediate priority is to
address the compromised oxygenation. Administering high-flow oxygen is the
first step in stabilizing the patient. While notifying the provider is essential, it is
secondary to immediate physiological support. The other options are either not
the priority or would delay urgent action.
6. A patient is receiving an intravenous infusion of heparin. The nurse is
reviewing the laboratory results. Which finding would be most indicative that
the therapy is at a therapeutic level?
TESTBANK WITH VERIFIED AND WELL DETAILED ANSWERS | PLUS RATIONALES
| DOWNLOAD AND PASS | LATEST EXAM UPDATE 2026/2027
Core Domains:
Pharmacology and Pharmacokinetics
Fluid and Electrolyte Balance
Acute and Chronic Cardiovascular Disorders
Respiratory Physiology and Pathophysiology
Neurological Assessment and Disorders
Endocrine System and Metabolism
Gastrointestinal and Hepatic Function
Renal and Urinary System Disorders
Evidence-Based Practice and Clinical Decision-Making
Legal, Ethical, and Professional Nursing Standards
Introduction
This comprehensive practice examination is designed to rigorously assess your
knowledge and clinical reasoning skills as you prepare for NSG 3600 Exam 2. It
covers a broad spectrum of essential nursing concepts, integrating foundational
theory with applied professional knowledge. The questions are presented in a
multiple-choice and scenario-based format to test not only recall but also your
capacity for critical thinking, clinical judgment, and real-world application. This
resource emphasizes evidence-based practice, patient safety, and the ethical and
legal frameworks that guide professional nursing. It is intended to identify
knowledge gaps, reinforce key concepts, and build confidence for the actual
examination.
,════════════════════════════════════
SECTION ONE: QUESTIONS 1–50
1. A patient is prescribed a medication that is a weak acid. Which of the
following conditions would most likely increase the rate of its absorption in the
gastrointestinal tract?
A. Administration with a high-fat meal
B. A higher pH in the stomach due to antacid use
C. A lower pH in the stomach due to gastric acid hypersecretion
D. The presence of food that slows gastric emptying
🟢 Correct Answer: C. A lower pH in the stomach due to gastric acid
hypersecretion
🔴 Explanation: Weak acids are predominantly non-ionized in acidic
environments, which is the form that readily crosses lipid membranes. A lower pH
(more acidic) facilitates this non-ionized state, thereby increasing absorption.
Antacids (higher pH) would decrease absorption. A high-fat meal and slowed
gastric emptying generally delay absorption.
2. A nurse is preparing to administer a drug that has a high first-pass effect.
Which route of administration should the nurse question to ensure therapeutic
effectiveness?
A. Sublingual
B. Oral
C. Intravenous
D. Transdermal
🟢 Correct Answer: B. Oral
,🔴 Explanation: The first-pass effect refers to the significant metabolism of a drug
by the liver before it reaches systemic circulation. Drugs administered orally are
absorbed from the GI tract and directly transported to the liver via the portal vein,
potentially reducing their bioavailability. Sublingual, intravenous, and transdermal
routes bypass this initial hepatic metabolism.
3. A patient in the intensive care unit is receiving intravenous furosemide for
pulmonary edema. Which of the following laboratory values should the nurse
monitor most closely during therapy?
A. Serum sodium
B. Serum potassium
C. Serum calcium
D. Serum albumin
🟢 Correct Answer: B. Serum potassium
🔴 Explanation: Furosemide is a loop diuretic that inhibits the reabsorption of
sodium, potassium, and chloride in the ascending loop of Henle. This results in a
significant loss of potassium, and therefore, hypokalemia is the most common
and clinically significant electrolyte imbalance associated with its use. Monitoring
serum potassium is a critical safety intervention.
4. A client with chronic hypertension is prescribed a beta-blocker. The nurse is
providing discharge instructions. Which statement by the client indicates a
need for further teaching?
A. "I will take my pulse daily before taking the medication."
B. "I must not stop this medication abruptly without my doctor's advice."
C. "I can take this medication with my morning orange juice."
D. "I should avoid over-the-counter cold remedies without checking with my
pharmacist."
, 🟢 Correct Answer: C. "I can take this medication with my morning orange juice."
🔴 Explanation: Grapefruit juice, not orange juice, is known to inhibit the CYP3A4
enzyme in the liver and intestinal wall, which is responsible for metabolizing many
beta-blockers. This can lead to increased drug levels and toxicity. The other
statements reflect correct understanding regarding self-monitoring, the risk of
rebound hypertension with abrupt cessation, and the need to avoid
sympathomimetics in OTC cold remedies.
5. A nurse is assessing a patient who is 24 hours post-operative following a
total hip arthroplasty. The patient's vital signs are: BP 110/70 mmHg, HR 92
bpm, RR 18/min, SpO2 94% on room air. The patient reports sudden onset of
chest pain and shortness of breath. What is the nurse's priority action?
A. Reassure the patient and encourage deep breathing exercises.
B. Administer oxygen via a non-rebreather mask.
C. Assess the patient for calf tenderness and swelling.
D. Notify the healthcare provider of the patient's symptoms.
🟢 Correct Answer: B. Administer oxygen via a non-rebreather mask.
🔴 Explanation: The patient's presentation is highly suspicious for a pulmonary
embolism (PE), a life-threatening complication. The immediate priority is to
address the compromised oxygenation. Administering high-flow oxygen is the
first step in stabilizing the patient. While notifying the provider is essential, it is
secondary to immediate physiological support. The other options are either not
the priority or would delay urgent action.
6. A patient is receiving an intravenous infusion of heparin. The nurse is
reviewing the laboratory results. Which finding would be most indicative that
the therapy is at a therapeutic level?
