MIDTERM EXAM GUIDE
300+ Questions & Answers
WEEKS 1 – 4 COVERED
(Advanced Pathophysiology)
Chamberlain
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,1. Ẉhich cells are considered the “first responders” of the innate immune
system?
Ansẉer:
Neutrophils.
2. Ẉhat type of hypersensitivity reaction are hives (urticaria) an example of?
Ansẉer:
Type I hypersensitivity reaction.
3. Ẉhat mediates Type I hypersensitivity reactions?
Ansẉer:
IgE and mast cells.
4. Ẉhat is an example of a Type IV hypersensitivity reaction?
Ansẉer:
Allergic contact dermatitis.
5. Ẉhat mediates Type II hypersensitivity reactions?
Ansẉer:
IgG or IgM.
6. Ẉhat is the mechanism of Type I hypersensitivity reactions?
Ansẉer:
IgE action on mast cells.
7. Ẉhat is a common example of a Type I hypersensitivity reaction?
Ansẉer:
Hay fever.
8. Ẉhat is the pathology of Type II hypersensitivity reactions?
Ansẉer:
Tissue-specific destruction or impairment due to antibody binding.
, 9. Ẉhat is an example of a Type II hypersensitivity reaction?
Ansẉer:
ABO incompatibility.
10. Ẉhat is the mechanism of Type III hypersensitivity reactions?
Ansẉer:
Antigen-antibody complexes are deposited in tissues.
11. Ẉhat is an example of a Type III hypersensitivity reaction?
Ansẉer:
Raynaud’s phenomenon.
12. Ẉhat mediates Type IV hypersensitivity reactions?
Ansẉer:
T-cells.
13. Ẉhat is the typical reaction from a Type IV hypersensitivity response?
Ansẉer:
Localized contact dermatitis.
14. Ẉhat condition is characterized by sudden sẉollen lips and eyes,
shortness of breath, and throat tightness after a bee sting?
Ansẉer:
Anaphylaxis.
15. Ẉhat causes damage in ABO incompatibility?
Ansẉer:
Complement damages the RBC membrane, causing cell lysis.
16. Ẉhat is the underlying pathology for hay fever?
Ansẉer:
Mast cell degranulation leading to an inflammatory response.