2026 HESI RN Pharmacology Exam
Test Bank EXAM 350 QUESTIONS WITH
COMPLETE SOLUTION WITH
RATIONALES) (MULTIPLE CHOICES)
(A+ GRADED 100% VERIFIED) LATEST
VERSION 2026/27
1. A male client who has been taking a high dose of a nonsteroidal anti
inflammatory drug (NSAID) comes to the clinic complaining of gastric
pain and blood in his stool. The healthcare provider discontinues the
NSAIDs and prescribes esomeprazole. Which information should the
client include in the nurse's teaching plan?
A. Once pain subsides, NSAID therapy can be continued
B. Resume a diet that consists of milk, cream, and bland foods
C. Notify the healthcare provider of the passage of black stool
D. Call the clinic if diarrhea or headache occur when taking
esomeprazole: C
E. 2. 2. When administering zolpidem to an older client, which
computer documentation indicates that the desired outcome has
been achieved?
A. Sleeps soundly through the night
B. Decreased episodes of incontinence
C. Exhibits fewer emotional outburst
D. Improved ability to concentrate: A
3. 3. A male client with a fungal infection of the toenail reports to the
nurse that he has been applying an over-the-counter triple antibiotic
ointment to the infection daily for two weeks without any
improvement.
Which action should the nurse take?
,A. Instruct the client to obtain a prescription for oral terbinafine
B. Suggest that the client use the ointment twice a day to be more
effective
C. Reassure that the treatment of fungus-infected toenails often takes
several months
D. Advise the client to obtain a prescription-strength formulation of the
ointment: A
4. A client with a nasogastric tube (NGT) has a prescription for
sucralfate. The liquid form of the medication is not currently available
in the pharmacy and tablets have been delivered to the medication
dispensing system. Which action should the nurse include when
administering the medication?
A. Crush the tablet and mix it with water separately from other
medications
B. Crush the tablet and mix it with other crushed tablets diluted in
water
C. Withhold the medication until a liquid form is available on the
nursing unitD. Crush the tablet and mix it with other liquid
medications for administration: A
5. A client with chronic asthma receives a prescription for montelukast,
a leukotriene modifier. Which statement by the client indicates to the
nurse that medication teaching was effective?
A. I should take this medication only when I am having an asthma
attack
B. I will take the tablet every evening to control my asthma
C. This medication will stop an asthma attack immediately
D. I will not need to use my inhalers twice a day when I start this
medication: 6. The nurse is planning to administer the antiulcer GI
agent sucralfate to a client with peptic ulcer disease. Which action
should the nurse include in this client's plan of care?
A. Assess for secondary Candida infection
B. Administer sucralfate once a day, preferably at bedtime
C. Give sucralfate on an empty stomach
,D. Monitor for electrolyte imbalance: B
7. A client with anemia secondary to chronic kidney disease (CKD)
started a prescription for epoetin alfa two months ago. Which client
finding best indicates that the medication is effective?
A. Reports of increased energy levels and decreased fatigue
B. Takes concurrent iron therapy without adverse effects
C. Food diary shows increased consumption of iron-rich foods
D. Hemoglobin level increased to 12 grams/dL(120 mmol/L): D
8. The healthcare provider prescribes propylthiouracil (PTU) and
Lugol's solution, a strong idoine solution, for a client with
hyperthyroidism. How should the nurse schedule the administration of
these medications?
A. Administer iodine one hour before PTU
B. Offer both drugs together with a meal
C. Schedule both medications at bedtime
D. Give parental dose once every 24 hours: B
9. Twenty minutes after the nurse starts a secondary IV infusion of
cefepime 2 grams using an infusion pump to deliver the dose in one
hour, the client reports feeling nauseated. Which action should the
nurse implement? A. Continue the infusion and administer a PRN
antiemetic prescription B. Stop the medication infusion and notify the
healthcare provider of the adverse effect
C. Reassure the client that the nausea us not related to the IV infusion
D. Increase the rate of the infusion to complete the dose of the
medication more rapidly: A
10. A client with diabetic peripheral neuropathy, who has been taking
pregabalin for 2 weeks reports diminished foot pain. The nurse notes
that there is no improvement in the healing of several toe ulcerations.
Which action should the nurse take?
A. Review the plan of care for strategies used to manage the foot
ulcerations
B. Reassure the client that diabetic foot ulcers take several months to
heal
, C. Explain that the medication dosage will probably need to be
increased
D. Withhold the next dose of the drug until the healthcare provider is
notified-
:A
11. A client with type 2 diabetes mellitus who takes glimepiride by
mouth daily calls the nurse to report a recent onset of nausea,
vomiting and diarrhea.
Which response should the nurse provide?
A. Increases oral fluid intake until these symptoms
subside. B. Use insulin sliding scale until symptoms are
resolved
C. Schedule a visit for evaluation by the healthcare provider
D. Return to the clinic for laboratory test for an infection: A
12. The healthcare provider increases a client's prescription for
glipizide 5mg to glipizide 7.5 mg by mouth every 12 hours. The
medication is available in 5 mg scored tablets. How many tablets
should the nurse administer with each dose?: 1.5
13. The nurse is administering the muscle relaxant baclofen PO to a
client diagnosed with multiple sclerosis. Which interventions should
the nurse implement?
A. Advise the client to move slowly and cautiously when rising and
walking B. Ensure the client knows to stop baclofen before using other
antispasmodics
C. Monitor intake and output every 8 hours
D. Evaluate muscle strength every 4 hours: D
14. The nurse retrieves hydromorphone 4 mg/ml from the Pyxis
Medstation, an automated dispensing system, for a client who is
receiving hydromorphone 3 mg IM every 8 hours PRN severe pain. How
many mL should the nurse administer to the client? (Round to the
nearest tenth): 0.8
15. A patient with hepatic encephalopathy is receiving lactulose.
Which assessment provides the nurse with the best information to
Test Bank EXAM 350 QUESTIONS WITH
COMPLETE SOLUTION WITH
RATIONALES) (MULTIPLE CHOICES)
(A+ GRADED 100% VERIFIED) LATEST
VERSION 2026/27
1. A male client who has been taking a high dose of a nonsteroidal anti
inflammatory drug (NSAID) comes to the clinic complaining of gastric
pain and blood in his stool. The healthcare provider discontinues the
NSAIDs and prescribes esomeprazole. Which information should the
client include in the nurse's teaching plan?
A. Once pain subsides, NSAID therapy can be continued
B. Resume a diet that consists of milk, cream, and bland foods
C. Notify the healthcare provider of the passage of black stool
D. Call the clinic if diarrhea or headache occur when taking
esomeprazole: C
E. 2. 2. When administering zolpidem to an older client, which
computer documentation indicates that the desired outcome has
been achieved?
A. Sleeps soundly through the night
B. Decreased episodes of incontinence
C. Exhibits fewer emotional outburst
D. Improved ability to concentrate: A
3. 3. A male client with a fungal infection of the toenail reports to the
nurse that he has been applying an over-the-counter triple antibiotic
ointment to the infection daily for two weeks without any
improvement.
Which action should the nurse take?
,A. Instruct the client to obtain a prescription for oral terbinafine
B. Suggest that the client use the ointment twice a day to be more
effective
C. Reassure that the treatment of fungus-infected toenails often takes
several months
D. Advise the client to obtain a prescription-strength formulation of the
ointment: A
4. A client with a nasogastric tube (NGT) has a prescription for
sucralfate. The liquid form of the medication is not currently available
in the pharmacy and tablets have been delivered to the medication
dispensing system. Which action should the nurse include when
administering the medication?
A. Crush the tablet and mix it with water separately from other
medications
B. Crush the tablet and mix it with other crushed tablets diluted in
water
C. Withhold the medication until a liquid form is available on the
nursing unitD. Crush the tablet and mix it with other liquid
medications for administration: A
5. A client with chronic asthma receives a prescription for montelukast,
a leukotriene modifier. Which statement by the client indicates to the
nurse that medication teaching was effective?
A. I should take this medication only when I am having an asthma
attack
B. I will take the tablet every evening to control my asthma
C. This medication will stop an asthma attack immediately
D. I will not need to use my inhalers twice a day when I start this
medication: 6. The nurse is planning to administer the antiulcer GI
agent sucralfate to a client with peptic ulcer disease. Which action
should the nurse include in this client's plan of care?
A. Assess for secondary Candida infection
B. Administer sucralfate once a day, preferably at bedtime
C. Give sucralfate on an empty stomach
,D. Monitor for electrolyte imbalance: B
7. A client with anemia secondary to chronic kidney disease (CKD)
started a prescription for epoetin alfa two months ago. Which client
finding best indicates that the medication is effective?
A. Reports of increased energy levels and decreased fatigue
B. Takes concurrent iron therapy without adverse effects
C. Food diary shows increased consumption of iron-rich foods
D. Hemoglobin level increased to 12 grams/dL(120 mmol/L): D
8. The healthcare provider prescribes propylthiouracil (PTU) and
Lugol's solution, a strong idoine solution, for a client with
hyperthyroidism. How should the nurse schedule the administration of
these medications?
A. Administer iodine one hour before PTU
B. Offer both drugs together with a meal
C. Schedule both medications at bedtime
D. Give parental dose once every 24 hours: B
9. Twenty minutes after the nurse starts a secondary IV infusion of
cefepime 2 grams using an infusion pump to deliver the dose in one
hour, the client reports feeling nauseated. Which action should the
nurse implement? A. Continue the infusion and administer a PRN
antiemetic prescription B. Stop the medication infusion and notify the
healthcare provider of the adverse effect
C. Reassure the client that the nausea us not related to the IV infusion
D. Increase the rate of the infusion to complete the dose of the
medication more rapidly: A
10. A client with diabetic peripheral neuropathy, who has been taking
pregabalin for 2 weeks reports diminished foot pain. The nurse notes
that there is no improvement in the healing of several toe ulcerations.
Which action should the nurse take?
A. Review the plan of care for strategies used to manage the foot
ulcerations
B. Reassure the client that diabetic foot ulcers take several months to
heal
, C. Explain that the medication dosage will probably need to be
increased
D. Withhold the next dose of the drug until the healthcare provider is
notified-
:A
11. A client with type 2 diabetes mellitus who takes glimepiride by
mouth daily calls the nurse to report a recent onset of nausea,
vomiting and diarrhea.
Which response should the nurse provide?
A. Increases oral fluid intake until these symptoms
subside. B. Use insulin sliding scale until symptoms are
resolved
C. Schedule a visit for evaluation by the healthcare provider
D. Return to the clinic for laboratory test for an infection: A
12. The healthcare provider increases a client's prescription for
glipizide 5mg to glipizide 7.5 mg by mouth every 12 hours. The
medication is available in 5 mg scored tablets. How many tablets
should the nurse administer with each dose?: 1.5
13. The nurse is administering the muscle relaxant baclofen PO to a
client diagnosed with multiple sclerosis. Which interventions should
the nurse implement?
A. Advise the client to move slowly and cautiously when rising and
walking B. Ensure the client knows to stop baclofen before using other
antispasmodics
C. Monitor intake and output every 8 hours
D. Evaluate muscle strength every 4 hours: D
14. The nurse retrieves hydromorphone 4 mg/ml from the Pyxis
Medstation, an automated dispensing system, for a client who is
receiving hydromorphone 3 mg IM every 8 hours PRN severe pain. How
many mL should the nurse administer to the client? (Round to the
nearest tenth): 0.8
15. A patient with hepatic encephalopathy is receiving lactulose.
Which assessment provides the nurse with the best information to
