Pharmacology, Essentials for
Medication Safety, 3rd Edition,
Workman & LA Charity|| All
Chapters || Newest Edition
Absorption - answer- Movement of a drug from the outside of the body into the blood
stream.
Agonist - answer- An extrinsic drug that activates the receptor site of a cell and mimics
the actions of naturally occurring drugs.
Antagonist - answer- An extrinsic drug that blocks the receptor site of a cell, preventing
the naturally occurring substance from binding to the receptor.
Bioavailability - answer- The percentage of a drug dose that actually reaches the blood.
Black Box Warning - answer- A notice that a drug may produce serious or even life
threatening effects in some people in addition to its beneficial effects.
Cytoxic - answer- A drug action that is intended to kill a cell or organism.
Distribution - answer- The extent that a drug absorbed into the bloodstream spreads
into the three body water components.
Duration of Action - answer- The length of time a drug is present in the blood at or
above the level needed to produce an effect or response.
Extrinsic Drugs - answer- Drugs that are man made or derived from another species;
not made by the human body.
First pass loss - answer- Rapid inactivation or elimination of oral drugs as a result of
liver metabolism.
Generic Name - answer- National and international public drug name created by the
United States Adopted NamesCouncil to indicate the usual use or chemical composition
of a drug.
Half Life - answer- Time san needed for one half of a drug dose to be eliminated.
, High Alert Drug - answer- A drug that has an increased risk of causing patient harm if it
is used in error.
Loading Dose - answer- The first dose of a drug that is larger than all subsequent doses
of the same drug; used when it takes more drug to reach steady state that it does to
maintain it.
Mechanism of Action - answer- Exactly how, at the cellular level, a drug changes the
activity of a cell.
Minimum Effective
Concentration - answer- The smallest amount of drug necessary in the blood or target
tissue to result in a measurable intended action.
Percutaneous Route - answer- Movement of a drug from the outside of the body to the
inside through the skin or mucous membranes.
Pharmacodynamics - answer- Ways in which drugs work to change body function.
Pharmacokinetics - answer- How the body changes drugs; drug metabolism.
Physiologic Effects - answer- The change in body function as an income of the
mechanism of action off a drug.
Receptors - answer- Physical place on or in a cell where a drug can bind and interact.
Sequestration - answer- The trapping of drugs within certain body tissues, delaying their
elimination and extending their duration of action.
Steady State - answer- Point at which drug elimination is balance with drug entry,
resulting in a constant effective blood level of the drug.
Target Tissue - answer- The actual cells or tissues affected by the mechanism of action
or intended actions of a specific drug.
Transdermal - answer- Type of percutaneous drug delivery in which the drug is applied
to the skin, passes through the skin and enters the bloodstream.
Vaporized - answer- Changing of a drug from a liquid form to a gas that can be
absorbed into the body by inhalation.
A plan to improve or prevent a health problem that includes the use of drugs. - answer-
Drug therapy.
What factors does drug therapy involve? - answer- 1. Identifying the specific health
problem.