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NSG 6001 Advanced Health Assessment Practice
Midterm Exam
1. A 64-year-old male with a history of chronic obstructive
pulmonary disease (COPD) and tobacco use presents to
the clinic complaining of worsening shortness of breath
and a persistent productive cough over the past three
weeks. On physical examination, you note distant breath
sounds, hyperresonance to percussion, a prolonged
expiratory phase, and the use of accessory muscles during
respiration. Which of the following diagnostic findings is
most indicative of severe emphysema rather than chronic
bronchitis in this patient?
A) Markedly elevated hematocrit and early development of
cor pulmonale
B) Significant reduction in total lung capacity with normal
residual volume
C) Decreased diffusing capacity of the lung for carbon
monoxide (DLCO)
D) Prominent bronchovascular markings on a chest
radiograph
correct answer C) Decreased diffusing
capacity of the lung for carbon monoxide (DLCO)
Rationale: In emphysema, the destruction of alveolar
, walls reduces the surface area available for gas
exchange, leading to a decreased DLCO. In contrast,
chronic bronchitis primarily affects the airways, and
DLCO typically remains normal or near normal.
Elevated hematocrit and early cor pulmonale are more
characteristic of chronic bronchitis due to profound
hypoxemia.
2. A 45-year-old female presents for a routine annual
physical examination. During the cardiac auscultation, you
detect a mid-systolic click followed by a late systolic
murmur at the apex. The murmur increases in intensity
and duration when the patient stands up from a squatting
position, and decreases when she squats. Based on these
physical findings, which of the following is the most likely
underlying valvular pathology?
A) Mitral valve prolapse
B) Aortic stenosis
C) Mitral regurgitation
D) Hypertrophic cardiomyopathy
correct answer A) Mitral valve prolapse
Rationale: A mid-systolic click followed by a late
systolic murmur is the classic presentation of mitral valve
prolapse (MVP). Standing reduces venous return
(preload), which decreases left ventricular volume,
causing the valve leaflets to prolapse earlier in systole,
thereby lengthening and intensifying the murmur.
Squatting increases preload, delaying the prolapse and
softening the murmur.
3. A 29-year-old female patient presents with a 4-month
history of progressive fatigue, weight gain despite a poor
appetite, cold intolerance, generalized dry skin, and mild
constipation. On physical examination, you note delayed
relaxation of the deep tendon reflexes (woltman's sign)
and a non-tender, diffusely enlarged thyroid gland.
, Laboratory evaluation confirms primary hypothyroidism.
Which of the following is the most common etiology for
this condition in developed countries?
A) Iodine deficiency
B) Hashimoto's thyroiditis
C) Subacute granulomatous thyroiditis
D) Pituitary adenoma
correct answer B) Hashimoto's thyroiditis
Rationale: Chronic autoimmune thyroiditis
(Hashimoto's thyroiditis) is the most common cause of
primary hypothyroidism in iodine-sufficient, developed
nations. It is characterized by autoimmune destruction of
the thyroid gland, often presenting with a goiter and
positive antithyroid peroxidase (TPO) antibodies. Iodine
deficiency remains the leading cause globally but not in
developed regions.
4. During a cranial nerve assessment of a 72-year-old male
who recently suffered an ischemic cerebrovascular
accident (CVA), you observe that when the patient is asked
to protrude his tongue, it deviates significantly to the right
side. Additionally, you note muscle atrophy and
fasciculations on the right half of the tongue. Damage to
which cranial nerve and anatomical location is responsible
for this presentation?
A) Left Cranial Nerve XII (Hypoglossal) nuclear lesion
B) Right Cranial Nerve XII (Hypoglossal) peripheral or
nuclear lesion
C) Left Cranial Nerve VII (Facial) supranuclear lesion
D) Right Cranial Nerve IX (Glossopharyngeal) central
lesion
correct answer B) Right Cranial Nerve XII
(Hypoglossal) peripheral or nuclear lesion
Rationale: The hypoglossal nerve (CN XII) provides
motor innervation to the muscles of the tongue. A lower
, motor neuron or peripheral lesion of CN XII causes the
tongue to deviate toward the side of the lesion due to the
unopposed action of the contralateral genioglossus
muscle. Atrophy and fasciculations are classic signs of
lower motor neuron damage.
5. A 58-year-old postmenopausal female presents to the
clinic with complaints of severe, sharp, unilateral right-
sided headache localized around her temple, accompanied
by jaw claudication while chewing food and transient
blurred vision in her right eye. On examination, the right
temporal artery is prominent, nodular, tender, and
pulseless. What is the most immediate and critical next
step in the clinical management of this patient to prevent
permanent complications?
A) Order an urgent duplex ultrasound of the temporal
arteries and await results
B) Schedule a temporal artery biopsy within 48 hours and
hold medical therapy
C) Initiate immediate empirical high-dose systemic
corticosteroid therapy
D) Administer low-dose aspirin and schedule a follow-up
appointment in one week
correct answer C) Initiate immediate
empirical high-dose systemic corticosteroid
therapy
Rationale: The clinical presentation is highly suspicious
for Giant Cell Arteritis (Temporal Arteritis). The most
catastrophic complication is permanent vision loss due to
anterior ischemic optic neuropathy. Because of this
urgent risk, high-dose systemic corticosteroids (e.g.,
prednisone 40–60 mg daily) must be started immediately
based on clinical suspicion, without waiting for biopsy
confirmation.