NURS 5357 Neurobiology
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1. A 19-year-old female requires a hospital consultation after she was admitted following
an attempted suicide. Her family reports that she has been suffering from severe
depression for the last three years. What area of the brain may best be described as
hypothetically involved in her feelings of worthlessness and suicidality?
a) Nucleus accumbens
b) basal forebrain
c) Hypothalamus
d) Amygdala - Correct Answer: Amygdala
2. When norepinephrine binds to a presynaptic alpha 2 autoreceptor it stops further
release of norepinephrine.
True
False - Correct Answer: True
3. Which psychological manifestations of depression will improve in response to
antidepressant therapy?
a) Loss of energy
b) Social withdrawal
c) Sleep disturbances
d) Palpitations - Correct Answer: Social withdrawal
4. Which of the following brain regions is associated with symptoms of decreased pleasure
or interests, fatigue, and energy disturbances in depression?
a) Thalamus
b) Hippocampus
c) basal forebrain
, d) Nucleus accumbens - Correct Answer: Nucleus accumbens
5. Which brain region is associated with appetite and sleep disturbances seen with
depression?
6. Hypothalamus
7. Thalamus
8. basal forebrain
9. Striatum - Correct Answer: Hypothalamus
10. What brain region is associated with symptoms of decreased need for sleep and
hyperarousal with mania
(select all that apply)?
a) Basal Forebrain
b) Thalamus
c) Striatum
d) Hypothalamus - Correct Answer: the answer is NOT all
11. Under normal conditions, the Hypothalamic-Pituitary-Adrenal (HPA) axis is suppressed
by neurons from hippocampal and amygdala areas.
True
False - Correct Answer: True
12. Malfunctioning in the striatum hypothetically matches which of the following symptoms
seen in mania?
a) Mood lability
b) Decreased sleep/arousal
c) motor/agitation
d) Racing thoughts/goal directed/grandiosity - Correct Answer: the answer is NOT
Decreased sleep/arousal
13. Norepinephrine (NE) regulates serotonin (5HT) neurons via which of the following
pathways?
a) Alpha 2 receptors only
Comprehensive Resource To Help You Ace 2026-2027 Exams Includes
Frequently Tested Questions With ELABORATED 100% Correct
COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!! Current Update!!
1. A 19-year-old female requires a hospital consultation after she was admitted following
an attempted suicide. Her family reports that she has been suffering from severe
depression for the last three years. What area of the brain may best be described as
hypothetically involved in her feelings of worthlessness and suicidality?
a) Nucleus accumbens
b) basal forebrain
c) Hypothalamus
d) Amygdala - Correct Answer: Amygdala
2. When norepinephrine binds to a presynaptic alpha 2 autoreceptor it stops further
release of norepinephrine.
True
False - Correct Answer: True
3. Which psychological manifestations of depression will improve in response to
antidepressant therapy?
a) Loss of energy
b) Social withdrawal
c) Sleep disturbances
d) Palpitations - Correct Answer: Social withdrawal
4. Which of the following brain regions is associated with symptoms of decreased pleasure
or interests, fatigue, and energy disturbances in depression?
a) Thalamus
b) Hippocampus
c) basal forebrain
, d) Nucleus accumbens - Correct Answer: Nucleus accumbens
5. Which brain region is associated with appetite and sleep disturbances seen with
depression?
6. Hypothalamus
7. Thalamus
8. basal forebrain
9. Striatum - Correct Answer: Hypothalamus
10. What brain region is associated with symptoms of decreased need for sleep and
hyperarousal with mania
(select all that apply)?
a) Basal Forebrain
b) Thalamus
c) Striatum
d) Hypothalamus - Correct Answer: the answer is NOT all
11. Under normal conditions, the Hypothalamic-Pituitary-Adrenal (HPA) axis is suppressed
by neurons from hippocampal and amygdala areas.
True
False - Correct Answer: True
12. Malfunctioning in the striatum hypothetically matches which of the following symptoms
seen in mania?
a) Mood lability
b) Decreased sleep/arousal
c) motor/agitation
d) Racing thoughts/goal directed/grandiosity - Correct Answer: the answer is NOT
Decreased sleep/arousal
13. Norepinephrine (NE) regulates serotonin (5HT) neurons via which of the following
pathways?
a) Alpha 2 receptors only
