NURS 6630 PSYCHOPHARMACOLOGY QUESTIONS
AND ANSWERS SET A+
✔✔Six common side effects of SNRIs include: - ✔✔Insomnia, nausea, sexual
dysfunction, hypertension, sweating, headaches
✔✔Severe side effect of SNRIs in children/adolescents under age 25 years old: -
✔✔suicidal ideation
✔✔Life threatening adverse effect of SNRIs, especially when used in combination with
other serotonergic drugs: - ✔✔Serotonin Syndrome
✔✔This SNRI is an inhibitor of Cytochrome P450 enzymes: - ✔✔venlafaxine
✔✔This SNRI is hepatotoxic: - ✔✔duloxetine
✔✔MAOIs increase the levels of: - ✔✔Serotonin, Norepinephrine, and Dopamine
✔✔Norepinephrine regulates: - ✔✔alertness and focus
✔✔Dopamine regulates: - ✔✔cognitive function, motivation, and awakeness
✔✔In the synaptic cleft, Monoamine Oxidase A breaks down: - ✔✔Serotonin,
Norepinephrine, and Dopamine
✔✔In the synaptic cleft, Monoamine Oxidase B breaks down: - ✔✔Dopamine
✔✔MAOIs are especially effective in: - ✔✔Atypical depression (mood responds to
positive events and symptoms include increased appetite, weight gain, sleepiness, and
fatigue)
, ✔✔Non-selective MAOIs inhibit enzymes: - ✔✔MAO-A and MAO-B
✔✔Selective MAOIs only inhibit the enzyme: - ✔✔MAO-B
✔✔Three non-selective MAOIs: - ✔✔isocarboxazid, phenelzine, tranylcypromine
✔✔Non-selective MAOIs increase the levels of these neurotransmitters: - ✔✔Serotonin,
Norepinephrine, Dopamine
✔✔These three non-selective MAOIs bind irreversibly to MAO enzymes to permanently
block their function: - ✔✔isocarboxazid, phenelzine, tranylcypromine
✔✔Two selective MAOIs: - ✔✔selegeline, rasagiline
✔✔Selective MAOIs increase the level of this neurotransmitter: - ✔✔Dopamine
✔✔These selective MAOIs are more commonly prescribed to treat Parkinson's Disease
(a neurodegenerative disorder that effects the dopaminergic neurons in the substantia
nigra region of the brain): - ✔✔selegeline, rasagiline
✔✔Adverse effects of MAOIs include: - ✔✔Serotonin syndrome and hypertensive crisis
✔✔Before starting another antidepressant MAOIs should be stopped for at least: -
✔✔Two weeks (to allow for the body to replace MAO enzymes so that serotonin
syndrome does not occur)
✔✔Five main symptoms of hypertensive crisis: - ✔✔hyperthermia, hypertension,
tachycardia, arrhythmias, agitation
✔✔Hypertensive crisis commonly occurs when people taking MAOIs consume foods or
drinks high in: - ✔✔tyramine (cheese, wine, beer, cured/smoked meats)
✔✔Foods and drinks rich in tyramine: - ✔✔cheese, wine, beer, cured/smoked meats
✔✔When uninhibited, these two enzymes are responsible for breaking down tyramine: -
✔✔MAO-A and MAO-B
✔✔When tyramine is not broken down, it increases the release of this neurotransmitter,
which causes hypertensive crisis: - ✔✔Norepinephrine
✔✔Due to its action as an adrenergic antagonist this drug is the treatment of
hypertensive crisis: - ✔✔Phentolamine
AND ANSWERS SET A+
✔✔Six common side effects of SNRIs include: - ✔✔Insomnia, nausea, sexual
dysfunction, hypertension, sweating, headaches
✔✔Severe side effect of SNRIs in children/adolescents under age 25 years old: -
✔✔suicidal ideation
✔✔Life threatening adverse effect of SNRIs, especially when used in combination with
other serotonergic drugs: - ✔✔Serotonin Syndrome
✔✔This SNRI is an inhibitor of Cytochrome P450 enzymes: - ✔✔venlafaxine
✔✔This SNRI is hepatotoxic: - ✔✔duloxetine
✔✔MAOIs increase the levels of: - ✔✔Serotonin, Norepinephrine, and Dopamine
✔✔Norepinephrine regulates: - ✔✔alertness and focus
✔✔Dopamine regulates: - ✔✔cognitive function, motivation, and awakeness
✔✔In the synaptic cleft, Monoamine Oxidase A breaks down: - ✔✔Serotonin,
Norepinephrine, and Dopamine
✔✔In the synaptic cleft, Monoamine Oxidase B breaks down: - ✔✔Dopamine
✔✔MAOIs are especially effective in: - ✔✔Atypical depression (mood responds to
positive events and symptoms include increased appetite, weight gain, sleepiness, and
fatigue)
, ✔✔Non-selective MAOIs inhibit enzymes: - ✔✔MAO-A and MAO-B
✔✔Selective MAOIs only inhibit the enzyme: - ✔✔MAO-B
✔✔Three non-selective MAOIs: - ✔✔isocarboxazid, phenelzine, tranylcypromine
✔✔Non-selective MAOIs increase the levels of these neurotransmitters: - ✔✔Serotonin,
Norepinephrine, Dopamine
✔✔These three non-selective MAOIs bind irreversibly to MAO enzymes to permanently
block their function: - ✔✔isocarboxazid, phenelzine, tranylcypromine
✔✔Two selective MAOIs: - ✔✔selegeline, rasagiline
✔✔Selective MAOIs increase the level of this neurotransmitter: - ✔✔Dopamine
✔✔These selective MAOIs are more commonly prescribed to treat Parkinson's Disease
(a neurodegenerative disorder that effects the dopaminergic neurons in the substantia
nigra region of the brain): - ✔✔selegeline, rasagiline
✔✔Adverse effects of MAOIs include: - ✔✔Serotonin syndrome and hypertensive crisis
✔✔Before starting another antidepressant MAOIs should be stopped for at least: -
✔✔Two weeks (to allow for the body to replace MAO enzymes so that serotonin
syndrome does not occur)
✔✔Five main symptoms of hypertensive crisis: - ✔✔hyperthermia, hypertension,
tachycardia, arrhythmias, agitation
✔✔Hypertensive crisis commonly occurs when people taking MAOIs consume foods or
drinks high in: - ✔✔tyramine (cheese, wine, beer, cured/smoked meats)
✔✔Foods and drinks rich in tyramine: - ✔✔cheese, wine, beer, cured/smoked meats
✔✔When uninhibited, these two enzymes are responsible for breaking down tyramine: -
✔✔MAO-A and MAO-B
✔✔When tyramine is not broken down, it increases the release of this neurotransmitter,
which causes hypertensive crisis: - ✔✔Norepinephrine
✔✔Due to its action as an adrenergic antagonist this drug is the treatment of
hypertensive crisis: - ✔✔Phentolamine
