LCAS CORE MAIN QUESTIONS AND ANSWERS SURE
A+
✔✔Motivational enhancement - ✔✔form of behavioral therapy; capitalizes on readiness
of individuals to change their behavior and enter treatment
✔✔Motivational incentives - ✔✔form of behavioral therapy; uses positive reinforcement
to encourage abstinence from drugs
✔✔Disulfiram (Antabuse) - ✔✔first medication approved by FDA to treat chronic alcohol
dependence; alcohol-aversive or alcohol-sensitizing agent; does not affect brain
receptors directly
✔✔true - ✔✔Disulfiram (Antabuse) is most effective for pts. who have undergone
detoxification or are in initiation stage of abstinence, especially when committed to
abstinence and receive adequate, ongoing supervision
✔✔Oral naltrexone (Revia) - ✔✔relatively long-lasting opioid antagonist; used to treat
opioid dependence for many years and used to treat alcohol dependence sine 1994;
reduces both the rewarding effects of alcohol and craving for it
✔✔Agonist - ✔✔a chemical that binds to the receptor and activates the receptor to
produce a biological response
✔✔Antagonist - ✔✔a chemical that blocks the action of a drug by attaching to the
receptors in the brain without activating them
✔✔Disulfarim (Antabuse) - ✔✔contraindications include known hypersensitivity to this
drug, sulfur or nickel allergy, psychosis, severe myocardial and/or coronary occlusion,
pregnant or nursing
, ✔✔Naltrexone - ✔✔contraindications include current illicit opioid use or methadone
maintenance therapy, current opioid withdrawal, acute hepatitis or liver failure,
anticipated need for opioid analgesics within next 7 days, history of sensitivity to the
drug
✔✔Analgesic - ✔✔painkillers or drugs related to pain or alleviating pain
✔✔Disfulfiram-alcohol reaction - ✔✔moderate symptoms include: sweating, warmth and
flushing, hyperventilation, respiratory difficulty/shortness of breath, blurred vision, head
and neck throbbing, thirst, nausea/vomiting, chest pain/palpitations, hypotension,
tachycardia, vertigo, fainting, marked uneasiness, confusion, and weakness;
severe sx include: respiratory depression, cardiovascular collapse, arrhythmia,
myocardial infarction (heart attack), acute congestive heart failure, seizures,
unconsciousness, and death
✔✔Disfulfiram (Antabuse) - ✔✔most common side effects include skin/acneiform
eruptions, allergic dermatitis, mild drowsiness, fatigue, headache, impotence, metallic or
garlic-like aftertaste
✔✔Oral naltrexone (Revia) - ✔✔most common side effects include nausea, vomiting,
headache, dizziness, fatigue, nervousness, anxiety, somnolence (drowsiness)
✔✔Oral Naltrexone (Revia) - ✔✔drug interactions include cough/cold medications,
antidiarrheal medications, opioid analgesics, thioridazine, Yohimbine, NSAIDs
✔✔Extended-release Injectable Naltrexone (Vivitrol) - ✔✔extended-release medication
for opioid dependence and/or alcohol dependence that addresses patient compliance;
administered once a month through intramuscular injections
✔✔Extended-release Injectable Naltrexone - ✔✔side effects include injection site
reactions, nausea, vomiting, headache, dizziness, fatigue, back pain, upper abdominal
pain, and decreased appetite
✔✔Extended-release Injectable Naltrexone - ✔✔contraindications include patient
obesity, anticipated need for opioid analgesics in next 30 days, and histor of sensitivity
to PLG, carboxymethylcellulose, or any components of diluent
✔✔Acamprosate (Campral) - ✔✔third drug to receive FDA approval for postwithdrawal
maintenance of alcohol abstinence; mechanism of action not clearly established, but it
is thought to help modulate and normalize alcohol-related changes in brain activity,
thereby reducing symptoms of postacute withdrawal, such as sleep disturbances and
mood, that may trigger relapse to drinking
A+
✔✔Motivational enhancement - ✔✔form of behavioral therapy; capitalizes on readiness
of individuals to change their behavior and enter treatment
✔✔Motivational incentives - ✔✔form of behavioral therapy; uses positive reinforcement
to encourage abstinence from drugs
✔✔Disulfiram (Antabuse) - ✔✔first medication approved by FDA to treat chronic alcohol
dependence; alcohol-aversive or alcohol-sensitizing agent; does not affect brain
receptors directly
✔✔true - ✔✔Disulfiram (Antabuse) is most effective for pts. who have undergone
detoxification or are in initiation stage of abstinence, especially when committed to
abstinence and receive adequate, ongoing supervision
✔✔Oral naltrexone (Revia) - ✔✔relatively long-lasting opioid antagonist; used to treat
opioid dependence for many years and used to treat alcohol dependence sine 1994;
reduces both the rewarding effects of alcohol and craving for it
✔✔Agonist - ✔✔a chemical that binds to the receptor and activates the receptor to
produce a biological response
✔✔Antagonist - ✔✔a chemical that blocks the action of a drug by attaching to the
receptors in the brain without activating them
✔✔Disulfarim (Antabuse) - ✔✔contraindications include known hypersensitivity to this
drug, sulfur or nickel allergy, psychosis, severe myocardial and/or coronary occlusion,
pregnant or nursing
, ✔✔Naltrexone - ✔✔contraindications include current illicit opioid use or methadone
maintenance therapy, current opioid withdrawal, acute hepatitis or liver failure,
anticipated need for opioid analgesics within next 7 days, history of sensitivity to the
drug
✔✔Analgesic - ✔✔painkillers or drugs related to pain or alleviating pain
✔✔Disfulfiram-alcohol reaction - ✔✔moderate symptoms include: sweating, warmth and
flushing, hyperventilation, respiratory difficulty/shortness of breath, blurred vision, head
and neck throbbing, thirst, nausea/vomiting, chest pain/palpitations, hypotension,
tachycardia, vertigo, fainting, marked uneasiness, confusion, and weakness;
severe sx include: respiratory depression, cardiovascular collapse, arrhythmia,
myocardial infarction (heart attack), acute congestive heart failure, seizures,
unconsciousness, and death
✔✔Disfulfiram (Antabuse) - ✔✔most common side effects include skin/acneiform
eruptions, allergic dermatitis, mild drowsiness, fatigue, headache, impotence, metallic or
garlic-like aftertaste
✔✔Oral naltrexone (Revia) - ✔✔most common side effects include nausea, vomiting,
headache, dizziness, fatigue, nervousness, anxiety, somnolence (drowsiness)
✔✔Oral Naltrexone (Revia) - ✔✔drug interactions include cough/cold medications,
antidiarrheal medications, opioid analgesics, thioridazine, Yohimbine, NSAIDs
✔✔Extended-release Injectable Naltrexone (Vivitrol) - ✔✔extended-release medication
for opioid dependence and/or alcohol dependence that addresses patient compliance;
administered once a month through intramuscular injections
✔✔Extended-release Injectable Naltrexone - ✔✔side effects include injection site
reactions, nausea, vomiting, headache, dizziness, fatigue, back pain, upper abdominal
pain, and decreased appetite
✔✔Extended-release Injectable Naltrexone - ✔✔contraindications include patient
obesity, anticipated need for opioid analgesics in next 30 days, and histor of sensitivity
to PLG, carboxymethylcellulose, or any components of diluent
✔✔Acamprosate (Campral) - ✔✔third drug to receive FDA approval for postwithdrawal
maintenance of alcohol abstinence; mechanism of action not clearly established, but it
is thought to help modulate and normalize alcohol-related changes in brain activity,
thereby reducing symptoms of postacute withdrawal, such as sleep disturbances and
mood, that may trigger relapse to drinking
