ANCC FNP-BC Certification Exam Prep | 500+ Most Tested
QUESTIONs with Correct Answers & Expert Rationales
2026/2027
QUESTION 1
A 45-year-old male presents with chronic gastroesophageal reflux
disease (GERD). Endoscopy reveals Barrett esophagus. The nurse
practitioner recognizes that Barrett esophagus is an example of which
cellular adaptation?
A. Atrophy
B. Hyperplasia
C. Metaplasia
D. Dysplasia
Correct Answer: C. Metaplasia
,Rationale: Barrett esophagus involves the replacement of normal
stratified squamous epithelium with columnar epithelium due to
chronic acid irritation.
QUESTION 2
Which of the following clinical findings is most characteristic of
trigeminal neuralgia (tic douloureux)?
A. Continuous, dull, aching facial pain lasting for several hours
B. Unilateral, brief, electric shock-like pains triggered by light touch
C. Bilateral facial numbness and progressive muscle weakness
D. Loss of corneal reflex accompanied by drooping of the eyelid
Correct Answer: B. Unilateral, brief, electric shock-like pains triggered by
light touch
Rationale: Trigeminal neuralgia is characterized by sudden, severe, brief,
stabbing pain along the distribution of the trigeminal nerve, often
triggered by innocuous stimuli.
,QUESTION 3
A 68-year-old female presents with a 3-month history of progressive
proximal muscle weakness in her shoulders and hips, along with a
heliotrope rash on her eyelids and Gottron papules on her knuckles.
Which diagnostic test is most specific for confirming this diagnosis?
A. Erythrocyte sedimentation rate (ESR)
B. Serum creatine kinase (CK)
C. Anti-Jo-1 antibodies
D. Rheumatoid factor
Correct Answer: C. Anti-Jo-1 antibodies
Rationale: Dermatomyositis is characterized by proximal muscle
weakness and characteristic skin rashes. Anti-Jo-1 antibodies are highly
specific for inflammatory myopathies.
, QUESTION 4
Which of the following blood pressure readings defines Stage 1
hypertension according to current guidelines?
A. 120-129 / less than 80 mmHg
B. 130--89 mmHg
C. 140 or higher / 90 or higher mmHg
D. 180 or higher / 120 or higher mmHg
Correct Answer: B. 130--89 mmHg
Rationale: Stage 1 hypertension is defined as a systolic blood pressure
of 130-139 mmHg or a diastolic blood pressure of 80-89 mmHg.
QUESTION 5
QUESTIONs with Correct Answers & Expert Rationales
2026/2027
QUESTION 1
A 45-year-old male presents with chronic gastroesophageal reflux
disease (GERD). Endoscopy reveals Barrett esophagus. The nurse
practitioner recognizes that Barrett esophagus is an example of which
cellular adaptation?
A. Atrophy
B. Hyperplasia
C. Metaplasia
D. Dysplasia
Correct Answer: C. Metaplasia
,Rationale: Barrett esophagus involves the replacement of normal
stratified squamous epithelium with columnar epithelium due to
chronic acid irritation.
QUESTION 2
Which of the following clinical findings is most characteristic of
trigeminal neuralgia (tic douloureux)?
A. Continuous, dull, aching facial pain lasting for several hours
B. Unilateral, brief, electric shock-like pains triggered by light touch
C. Bilateral facial numbness and progressive muscle weakness
D. Loss of corneal reflex accompanied by drooping of the eyelid
Correct Answer: B. Unilateral, brief, electric shock-like pains triggered by
light touch
Rationale: Trigeminal neuralgia is characterized by sudden, severe, brief,
stabbing pain along the distribution of the trigeminal nerve, often
triggered by innocuous stimuli.
,QUESTION 3
A 68-year-old female presents with a 3-month history of progressive
proximal muscle weakness in her shoulders and hips, along with a
heliotrope rash on her eyelids and Gottron papules on her knuckles.
Which diagnostic test is most specific for confirming this diagnosis?
A. Erythrocyte sedimentation rate (ESR)
B. Serum creatine kinase (CK)
C. Anti-Jo-1 antibodies
D. Rheumatoid factor
Correct Answer: C. Anti-Jo-1 antibodies
Rationale: Dermatomyositis is characterized by proximal muscle
weakness and characteristic skin rashes. Anti-Jo-1 antibodies are highly
specific for inflammatory myopathies.
, QUESTION 4
Which of the following blood pressure readings defines Stage 1
hypertension according to current guidelines?
A. 120-129 / less than 80 mmHg
B. 130--89 mmHg
C. 140 or higher / 90 or higher mmHg
D. 180 or higher / 120 or higher mmHg
Correct Answer: B. 130--89 mmHg
Rationale: Stage 1 hypertension is defined as a systolic blood pressure
of 130-139 mmHg or a diastolic blood pressure of 80-89 mmHg.
QUESTION 5
