NR 507 ADVANCED PATHOPHYSIOLOGY MIDTERM QUESTIONS & ANSWERS 202… EXAM
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
NR 507 Advanced
Pathophysiology Midterm
Questions & Answers 2026-
2027 | Chamberlain
University
Verified Answers Exam Ready With Rationales
55 QUESTIONS
DOCUMENT OVERVIEW
This document provides 55 advanced pathophysiology exam questions with correct answers and
explanations, facilitating effective study and review. The content focuses on essential concepts in
pathophysiology, ensuring a comprehensive understanding of the subject. It is ideal for exam preparation,
course review, and certification study, offering students a reliable resource for mastering critical principles
in advanced nursing practice.
CONTENTS
Hypersensitivity Disorders Q1–Q8
Immunology and Autoimmunity Q9–Q13
Page 1
, Anemia and Hematology Q14–Q31
Heart Failure and Disorders Q32–Q43
Pulmonary Diseases Q44–Q55
E XA M Q U EST I O N S
Q1 QUESTION 1 OF 55
Hypersensitivity: Type 1
CORRECT ANSWER
Type 1: Allergic reaction, Mediated by IgE, Inflammation due to mast cell degranulation
Local symptoms:
-itching
-rash
Systemic symptoms:
-wheezing
Most dangerous = anaphylactic reaction
systemic response of hypotension, severe bronchoconstriction
Main treatment: epinephrine reverses the effects
Q2 QUESTION 2 OF 55
Hypersensitivity: Type 2
CORRECT ANSWER
Type 2: Cytotoxic reaction; tissue specific (ex: thyroid tissue)
Macrophages are the primary effectors cells involved
Can cause tissue damage or alter function
Grave's disease (hyperthyroidism) - example of altering thyroid function, but does not destroy thyroid tissue
Incompatible blood type- example of cell/tissue damage that occurs; severe transfusion reaction occurs and
the transfused erythrocytes are destroyed by agglutination or complement-mediated lysis.
Q3 QUESTION 3 OF 55
Page 2
, Type 1 Hypersensitivity VS. Type 2 Hypersensitivity
CORRECT ANSWER
Type 1 Hypersensitivity
Organ Specific
Antibody binds to the antigen on the cell surface
Type 2 Hypersensitivity
Not Organ Specific
Antibody binds to the soluble antigen outside the cell surface that was released into the blood or body fluids,
and the complex is then deposited in the tissues
Q4 QUESTION 4 OF 55
Hypersensitivity: Type 3 - Examples
CORRECT ANSWER
Rheumatoid arthritis: Antigen/antibodies are deposited in the joints
Systemic Lupus Erythematosus (SLE)- very closely related to autoimmunity- antigen/antibodies deposit in
organs that cause tissue damage
Q5 QUESTION 5 OF 55
Hypersensitivity: Type 4
CORRECT ANSWER
Delayed response
Does not involve antigen/antibody complexes like Types 1, 2 and 3
Is T-cell mediated
Q6 QUESTION 6 OF 55
Page 3
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
NR 507 Advanced
Pathophysiology Midterm
Questions & Answers 2026-
2027 | Chamberlain
University
Verified Answers Exam Ready With Rationales
55 QUESTIONS
DOCUMENT OVERVIEW
This document provides 55 advanced pathophysiology exam questions with correct answers and
explanations, facilitating effective study and review. The content focuses on essential concepts in
pathophysiology, ensuring a comprehensive understanding of the subject. It is ideal for exam preparation,
course review, and certification study, offering students a reliable resource for mastering critical principles
in advanced nursing practice.
CONTENTS
Hypersensitivity Disorders Q1–Q8
Immunology and Autoimmunity Q9–Q13
Page 1
, Anemia and Hematology Q14–Q31
Heart Failure and Disorders Q32–Q43
Pulmonary Diseases Q44–Q55
E XA M Q U EST I O N S
Q1 QUESTION 1 OF 55
Hypersensitivity: Type 1
CORRECT ANSWER
Type 1: Allergic reaction, Mediated by IgE, Inflammation due to mast cell degranulation
Local symptoms:
-itching
-rash
Systemic symptoms:
-wheezing
Most dangerous = anaphylactic reaction
systemic response of hypotension, severe bronchoconstriction
Main treatment: epinephrine reverses the effects
Q2 QUESTION 2 OF 55
Hypersensitivity: Type 2
CORRECT ANSWER
Type 2: Cytotoxic reaction; tissue specific (ex: thyroid tissue)
Macrophages are the primary effectors cells involved
Can cause tissue damage or alter function
Grave's disease (hyperthyroidism) - example of altering thyroid function, but does not destroy thyroid tissue
Incompatible blood type- example of cell/tissue damage that occurs; severe transfusion reaction occurs and
the transfused erythrocytes are destroyed by agglutination or complement-mediated lysis.
Q3 QUESTION 3 OF 55
Page 2
, Type 1 Hypersensitivity VS. Type 2 Hypersensitivity
CORRECT ANSWER
Type 1 Hypersensitivity
Organ Specific
Antibody binds to the antigen on the cell surface
Type 2 Hypersensitivity
Not Organ Specific
Antibody binds to the soluble antigen outside the cell surface that was released into the blood or body fluids,
and the complex is then deposited in the tissues
Q4 QUESTION 4 OF 55
Hypersensitivity: Type 3 - Examples
CORRECT ANSWER
Rheumatoid arthritis: Antigen/antibodies are deposited in the joints
Systemic Lupus Erythematosus (SLE)- very closely related to autoimmunity- antigen/antibodies deposit in
organs that cause tissue damage
Q5 QUESTION 5 OF 55
Hypersensitivity: Type 4
CORRECT ANSWER
Delayed response
Does not involve antigen/antibody complexes like Types 1, 2 and 3
Is T-cell mediated
Q6 QUESTION 6 OF 55
Page 3
