NSG 552 EXAM 1 FINAL EXAM SCRIPT
QUESTIONS AND ANSWERS REVIEW PACK
2026
◉ Electrolyte imbalance commonly associated wtih psychotropic
medication:
Answer: hyponatremia
◉ The time needed to clear 50% of drugs from the plasma:
Answer: half-life
◉ The process of becoming desensitized and less responsive to a
particular medication dose overtime necessitating an increase:
Answer: Drug tolerance/desensitization
◉ A ration describing toxic dose to effective dose:
Answer: Therapeutic index
◉ A chemical that binds to a receptor to produce a biologic
response:
Answer: Agonist
,◉ A chemical that binds to a receptor but does not fully activate the
receptor:
Answer: partial agonist
◉ A chemical that binds to a receptor, blocking it to inhibit a biologic
response:
Answer: Antagonist
◉ An agent that binds to the same receptor as an agonist but
induces an opposite biological response:
Answer: inverse agonist
◉ A usually undesired but forseeable effect that occurs regardless of
dose and often resolves after continued therapy:
Answer: side effect
◉ S/S opposite of what it was meant to treat:
Answer: paradoxical reaction
◉ CYP450 interactions are part of:
Answer: Metabolism
,◉ Escitalopram is a CYP450-3A4 substrate. If the PMHNP adds a
second medication that is a 3A4 inducer, what happens to the
escitalopram levels?
Answer: They decrease
◉ Binding
Answer: A protein, macromolecule, nucleic acid, or small molecule to
which a given drug binds, resulting in an alteration of the normal
function of the bound molecule and a desirable therapeutic effect.
◉ Affinity
Answer: the extent or fraction to which a drug binds to receptors at
any given drug concentration
◉ CYP450
Answer: Cytochrome P450 (CYP450), a large superfamily of heme-
thiolate proteins, are involved in the metabolism of both exogenous
and endogenous compounds
◉ Symptoms of schizophrenia are divided into these two categories:
Answer: Positive and negative
, ◉ T/F Antipsychotic polypharmacy can increase the risk of re-
hospitalization, diabetes, EPS, sedation, seizures, metabolic effects,
mortality, and sudden cardiac death.
Answer: T
◉ Alogia, anhedonia, avolition and cognitive symptoms:
Answer: Negative symptoms
◉ Delusions, hallucinations, hostility, grandiosity:
Answer: Positive Symptoms
◉ Another name for 1st generation antipsychotics:
Answer: Typical antipsychotics, FGA
◉ Another name for 2nd generation antipsychotics:
Answer: Atypical antipsychotics, SGA
◉ First line treatment for Schizophrenia:
Answer: Second-generation antipsychotics (except clozapine)
◉ This class is associated with fewer neurological side effects and
effective for both positive and negative symptoms:
QUESTIONS AND ANSWERS REVIEW PACK
2026
◉ Electrolyte imbalance commonly associated wtih psychotropic
medication:
Answer: hyponatremia
◉ The time needed to clear 50% of drugs from the plasma:
Answer: half-life
◉ The process of becoming desensitized and less responsive to a
particular medication dose overtime necessitating an increase:
Answer: Drug tolerance/desensitization
◉ A ration describing toxic dose to effective dose:
Answer: Therapeutic index
◉ A chemical that binds to a receptor to produce a biologic
response:
Answer: Agonist
,◉ A chemical that binds to a receptor but does not fully activate the
receptor:
Answer: partial agonist
◉ A chemical that binds to a receptor, blocking it to inhibit a biologic
response:
Answer: Antagonist
◉ An agent that binds to the same receptor as an agonist but
induces an opposite biological response:
Answer: inverse agonist
◉ A usually undesired but forseeable effect that occurs regardless of
dose and often resolves after continued therapy:
Answer: side effect
◉ S/S opposite of what it was meant to treat:
Answer: paradoxical reaction
◉ CYP450 interactions are part of:
Answer: Metabolism
,◉ Escitalopram is a CYP450-3A4 substrate. If the PMHNP adds a
second medication that is a 3A4 inducer, what happens to the
escitalopram levels?
Answer: They decrease
◉ Binding
Answer: A protein, macromolecule, nucleic acid, or small molecule to
which a given drug binds, resulting in an alteration of the normal
function of the bound molecule and a desirable therapeutic effect.
◉ Affinity
Answer: the extent or fraction to which a drug binds to receptors at
any given drug concentration
◉ CYP450
Answer: Cytochrome P450 (CYP450), a large superfamily of heme-
thiolate proteins, are involved in the metabolism of both exogenous
and endogenous compounds
◉ Symptoms of schizophrenia are divided into these two categories:
Answer: Positive and negative
, ◉ T/F Antipsychotic polypharmacy can increase the risk of re-
hospitalization, diabetes, EPS, sedation, seizures, metabolic effects,
mortality, and sudden cardiac death.
Answer: T
◉ Alogia, anhedonia, avolition and cognitive symptoms:
Answer: Negative symptoms
◉ Delusions, hallucinations, hostility, grandiosity:
Answer: Positive Symptoms
◉ Another name for 1st generation antipsychotics:
Answer: Typical antipsychotics, FGA
◉ Another name for 2nd generation antipsychotics:
Answer: Atypical antipsychotics, SGA
◉ First line treatment for Schizophrenia:
Answer: Second-generation antipsychotics (except clozapine)
◉ This class is associated with fewer neurological side effects and
effective for both positive and negative symptoms:
