Neuropharmacology Study
Guide
Stroke, Seizures, Parkinson’s & Alzheimer’s
Medications Exam Review
(2026/2027)
Complete Practice Questions and
Correct Detailed Answers with
Rationales | 100% Guaranteed Pass |
New Version
, Alteplase (Activase, Cathflo Activase) tPA / tissue plasminogen activator; Category:
Thrombolytic
Alteplase Mechanism of Action Converts plasminogen to plasmin; plasmin breaks
down clot-bound fibrin (fibrinolysis), dissolving the
clot.
Alteplase Indications / Use Acute ischemic stroke, acute myocardial infarction,
acute massive pulmonary embolism; small doses
used to restore function of clotted central venous
access devices.
Alteplase Dosage Notes Acute ischemic stroke: 0.9 mg/kg IV (max 90 mg)
over 60 minutes, with 10% given as an initial bolus
over 1 minute.
Alteplase Adverse Effects Bleeding (can be severe or fatal, especially at
puncture sites), hypersensitivity reactions, increased
dysrhythmia risk after reperfusion in MI.
Alteplase Contraindications / Active internal bleeding; recent intracranial/intraspinal
Precautions surgery or serious head trauma; current intracranial
hemorrhage or subarachnoid hemorrhage; severe
uncontrolled hypertension.
Alteplase Nursing Considerations CT scan MUST be done before giving to rule out
hemorrhage; frequent neuro checks; monitor closely
for bleeding; avoid IM injections and unnecessary
venipuncture; avoid abbreviating as 'tPA' (risk of
confusion with TNK/TPN).
Alteplase Client Teaching Report any signs of bleeding immediately;
understand the need for frequent monitoring during
and after the infusion.
Clopidogrel (Plavix) P2Y12 inhibitor; Category: Antiplatelet
Clopidogrel Mechanism of Action Antagonizes the P2Y12 subunit of the ADP receptor
on platelets, decreasing platelet activation at the site
of vessel injury.
Guide
Stroke, Seizures, Parkinson’s & Alzheimer’s
Medications Exam Review
(2026/2027)
Complete Practice Questions and
Correct Detailed Answers with
Rationales | 100% Guaranteed Pass |
New Version
, Alteplase (Activase, Cathflo Activase) tPA / tissue plasminogen activator; Category:
Thrombolytic
Alteplase Mechanism of Action Converts plasminogen to plasmin; plasmin breaks
down clot-bound fibrin (fibrinolysis), dissolving the
clot.
Alteplase Indications / Use Acute ischemic stroke, acute myocardial infarction,
acute massive pulmonary embolism; small doses
used to restore function of clotted central venous
access devices.
Alteplase Dosage Notes Acute ischemic stroke: 0.9 mg/kg IV (max 90 mg)
over 60 minutes, with 10% given as an initial bolus
over 1 minute.
Alteplase Adverse Effects Bleeding (can be severe or fatal, especially at
puncture sites), hypersensitivity reactions, increased
dysrhythmia risk after reperfusion in MI.
Alteplase Contraindications / Active internal bleeding; recent intracranial/intraspinal
Precautions surgery or serious head trauma; current intracranial
hemorrhage or subarachnoid hemorrhage; severe
uncontrolled hypertension.
Alteplase Nursing Considerations CT scan MUST be done before giving to rule out
hemorrhage; frequent neuro checks; monitor closely
for bleeding; avoid IM injections and unnecessary
venipuncture; avoid abbreviating as 'tPA' (risk of
confusion with TNK/TPN).
Alteplase Client Teaching Report any signs of bleeding immediately;
understand the need for frequent monitoring during
and after the infusion.
Clopidogrel (Plavix) P2Y12 inhibitor; Category: Antiplatelet
Clopidogrel Mechanism of Action Antagonizes the P2Y12 subunit of the ADP receptor
on platelets, decreasing platelet activation at the site
of vessel injury.
