NRNP /2026 Seraphin MidTerm
100+ Questions and Answers All
correct answers are highlighted
Course
NRNP 6665 Seraphin MidTerm Exam
1. A 58-year-old patient with type 2 diabetes has an A1C of 8.8% despite metformin therapy.
Which medication provides cardiovascular benefit?
A. Sulfonylurea
B. DPP-4 inhibitor
C. SGLT2 inhibitor ✅
D. Meglitinide
Answer: C
Rationale: SGLT2 inhibitors reduce cardiovascular events and slow CKD progression in
appropriate patients.
2. Which blood pressure reading meets the ACC/AHA definition of Stage 2 hypertension?
A. 126/78 mmHg
B. 134/82 mmHg
C. 138/88 mmHg
D. 146/94 mmHg ✅
Answer: D
Rationale: Stage 2 hypertension is ≥140 systolic or ≥90 diastolic.
3. Which lipid-lowering medication is first-line for most patients with elevated ASCVD risk?
A. Niacin
B. Statin ✅
C. Ezetimibe
D. Bile acid sequestrant
,Answer: B
Rationale: Statins remain first-line therapy for ASCVD prevention.
4. A patient presents with sudden unilateral facial droop, arm weakness, and slurred speech.
What is the priority?
A. Schedule outpatient CT
B. Prescribe aspirin tomorrow
C. Activate emergency stroke protocol ✅
D. Observe for 24 hours
Answer: C
Rationale: Possible acute stroke requires immediate emergency evaluation.
5. Which vaccine is recommended annually for adults?
A. Hepatitis A
B. Influenza ✅
C. HPV
D. MMR
Answer: B
Rationale: Annual influenza vaccination is recommended for nearly all adults.
6. Which laboratory value best evaluates long-term glycemic control?
A. Fasting glucose
B. Random glucose
C. Hemoglobin A1C ✅
D. C-peptide
Answer: C
,Rationale: A1C reflects average glucose over approximately three months.
7. A patient reports crushing substernal chest pain radiating to the left arm. Which diagnosis
is most concerning?
A. GERD
B. Costochondritis
C. Acute myocardial infarction ✅
D. Panic attack
Answer: C
Rationale: Classic ischemic chest pain requires immediate evaluation.
8. Which organism most commonly causes uncomplicated urinary tract infections?
A. Klebsiella
B. Escherichia coli ✅
C. Enterococcus
D. Proteus
Answer: B
Rationale: E. coli causes the majority of uncomplicated UTIs.
9. Which thyroid laboratory pattern suggests primary hypothyroidism?
A. Low TSH, high T4
B. High TSH, low free T4 ✅
C. Low TSH, normal T4
D. Normal TSH, elevated T4
Answer: B
Rationale: Primary thyroid failure results in elevated TSH with decreased thyroid hormone.
, 10. Which inhaler is considered a rescue medication?
A. Fluticasone
B. Budesonide
C. Albuterol ✅
D. Tiotropium
Answer: C
Rationale: Short-acting beta₂ agonists rapidly relieve bronchospasm.
11. Which symptom is most associated with hyperthyroidism?
A. Weight gain
B. Heat intolerance ✅
C. Bradycardia
D. Constipation
Answer: B
Rationale: Hyperthyroidism increases metabolism and heat production.
12. Which antihypertensive class is contraindicated during pregnancy?
A. Methyldopa
B. Labetalol
C. Nifedipine
D. ACE inhibitors ✅
Answer: D
Rationale: ACE inhibitors are teratogenic.
13. Which laboratory marker is most specific for myocardial injury?
100+ Questions and Answers All
correct answers are highlighted
Course
NRNP 6665 Seraphin MidTerm Exam
1. A 58-year-old patient with type 2 diabetes has an A1C of 8.8% despite metformin therapy.
Which medication provides cardiovascular benefit?
A. Sulfonylurea
B. DPP-4 inhibitor
C. SGLT2 inhibitor ✅
D. Meglitinide
Answer: C
Rationale: SGLT2 inhibitors reduce cardiovascular events and slow CKD progression in
appropriate patients.
2. Which blood pressure reading meets the ACC/AHA definition of Stage 2 hypertension?
A. 126/78 mmHg
B. 134/82 mmHg
C. 138/88 mmHg
D. 146/94 mmHg ✅
Answer: D
Rationale: Stage 2 hypertension is ≥140 systolic or ≥90 diastolic.
3. Which lipid-lowering medication is first-line for most patients with elevated ASCVD risk?
A. Niacin
B. Statin ✅
C. Ezetimibe
D. Bile acid sequestrant
,Answer: B
Rationale: Statins remain first-line therapy for ASCVD prevention.
4. A patient presents with sudden unilateral facial droop, arm weakness, and slurred speech.
What is the priority?
A. Schedule outpatient CT
B. Prescribe aspirin tomorrow
C. Activate emergency stroke protocol ✅
D. Observe for 24 hours
Answer: C
Rationale: Possible acute stroke requires immediate emergency evaluation.
5. Which vaccine is recommended annually for adults?
A. Hepatitis A
B. Influenza ✅
C. HPV
D. MMR
Answer: B
Rationale: Annual influenza vaccination is recommended for nearly all adults.
6. Which laboratory value best evaluates long-term glycemic control?
A. Fasting glucose
B. Random glucose
C. Hemoglobin A1C ✅
D. C-peptide
Answer: C
,Rationale: A1C reflects average glucose over approximately three months.
7. A patient reports crushing substernal chest pain radiating to the left arm. Which diagnosis
is most concerning?
A. GERD
B. Costochondritis
C. Acute myocardial infarction ✅
D. Panic attack
Answer: C
Rationale: Classic ischemic chest pain requires immediate evaluation.
8. Which organism most commonly causes uncomplicated urinary tract infections?
A. Klebsiella
B. Escherichia coli ✅
C. Enterococcus
D. Proteus
Answer: B
Rationale: E. coli causes the majority of uncomplicated UTIs.
9. Which thyroid laboratory pattern suggests primary hypothyroidism?
A. Low TSH, high T4
B. High TSH, low free T4 ✅
C. Low TSH, normal T4
D. Normal TSH, elevated T4
Answer: B
Rationale: Primary thyroid failure results in elevated TSH with decreased thyroid hormone.
, 10. Which inhaler is considered a rescue medication?
A. Fluticasone
B. Budesonide
C. Albuterol ✅
D. Tiotropium
Answer: C
Rationale: Short-acting beta₂ agonists rapidly relieve bronchospasm.
11. Which symptom is most associated with hyperthyroidism?
A. Weight gain
B. Heat intolerance ✅
C. Bradycardia
D. Constipation
Answer: B
Rationale: Hyperthyroidism increases metabolism and heat production.
12. Which antihypertensive class is contraindicated during pregnancy?
A. Methyldopa
B. Labetalol
C. Nifedipine
D. ACE inhibitors ✅
Answer: D
Rationale: ACE inhibitors are teratogenic.
13. Which laboratory marker is most specific for myocardial injury?
