CPJE EXAM 3 COMPREHENSIVE CALIFORNIA
PHARMACY JURISPRUDENCE STUDY GUIDE
2026
◉ HLA b1502.
Answer: Test in Asians. Rash for carbamazepine (tegretol),
phenytoin (Dilantin), fos phenytoin (cerebyx)
◉ Trastuzumab.
Answer: Herceptin, her/Neu- ado-trastuzunab (kadcyla), lapatinib
(tykerb) pertuzumab (perjeta)
◉ Hla- b 5701.
Answer: Don't give abacavir (ziagen), epzicom, trizivir
◉ Not cross reactive a/ opioid allergy.
Answer: Fentanyl, meperidine (Demerol), methadone (dolophine),
tramadol (ultram), tapentadol (nucynta)
◉ Inducers.
Answer: Ps porcs (phenytoin, smoking, phenobarbital,
oxcarbazepine, rifampin, carbamazepine, St. John's wort)
,◉ Inhibitors.
Answer: Gpacman (grapefruit, pi's, azoles, cimetidine/cyclosporine,
macrolides- erytho/clarithro, amiodarone, non dihydro (dilt,
verapamil)
◉ If on amiodarone, decrease these drugs by 30-50%.
Answer: Digoxin, warfarin, quinidine, procainanide, statins
◉ Statins with high risk of inhibition.
Answer: Las (lova, atorva, simva)
◉ Entecavir.
Answer: Baraclude. Empty stomach for hep B that fail lamivudime
and adefovir- se: peripheral edema, nephrotoxic
◉ Ribavirin.
Answer: Copegus. W/ food bid for hep c, hepatotoxic, hemolytic
anemia, preg x, psych disorders, ci: renal disfxn
◉ Glipizide.
Answer: Glucotrol 30 min before break & dinner
,◉ Glimeprimide.
Answer: Amaryl 1-2 mg qd w/ 1st meal
◉ Glyburide.
Answer: Diabeta, + metformin = glucovance, do not use w/ renal
failure 2.5-5mg qd
◉ Rosiglitazone.
Answer: Avandia 4-8mg qd (tzd, exacerbate hf, liver damage,
increases hdl, decreases tg/total cholesterol) similar: pioglitazone
(actos)
◉ Repaglinide.
Answer: Prandin 0.5-2mg TID 15-30 min before a meal,
hypoglycemia- do not take with su's
◉ Nateglinide.
Answer: Starlix injection- 15-30 min before meals
◉ Acarbose.
Answer: Precose- w/ 1st bite of meal and water
◉ Miglitol.
, Answer: Glyset w/ 1st bite of meal and water
◉ Linagliptan.
Answer: Tradjenta- 5 mg qd in morning with or without food, no
renal adjustment
◉ Saxagliptin.
Answer: OnglyZa 2.5-5mg qd
◉ Canaglifozin.
Answer: Invokana 100mg qd before first meal of day for DM. Se:
female genital mycotic infxn, increased urination, hyperkalemia, can
increase dig levels, ci: renal dx
◉ Exenatide.
Answer: Byetta 30-60 min before am & pm meals,medguide,
pancreatitis, thyroid c-cell carcinoma xr= bydureon
◉ Liraglutide.
Answer: Victoza QD thyroid c-cell carcinoma, more weight loss, less
pancreatitis
◉ Pramlintide.
PHARMACY JURISPRUDENCE STUDY GUIDE
2026
◉ HLA b1502.
Answer: Test in Asians. Rash for carbamazepine (tegretol),
phenytoin (Dilantin), fos phenytoin (cerebyx)
◉ Trastuzumab.
Answer: Herceptin, her/Neu- ado-trastuzunab (kadcyla), lapatinib
(tykerb) pertuzumab (perjeta)
◉ Hla- b 5701.
Answer: Don't give abacavir (ziagen), epzicom, trizivir
◉ Not cross reactive a/ opioid allergy.
Answer: Fentanyl, meperidine (Demerol), methadone (dolophine),
tramadol (ultram), tapentadol (nucynta)
◉ Inducers.
Answer: Ps porcs (phenytoin, smoking, phenobarbital,
oxcarbazepine, rifampin, carbamazepine, St. John's wort)
,◉ Inhibitors.
Answer: Gpacman (grapefruit, pi's, azoles, cimetidine/cyclosporine,
macrolides- erytho/clarithro, amiodarone, non dihydro (dilt,
verapamil)
◉ If on amiodarone, decrease these drugs by 30-50%.
Answer: Digoxin, warfarin, quinidine, procainanide, statins
◉ Statins with high risk of inhibition.
Answer: Las (lova, atorva, simva)
◉ Entecavir.
Answer: Baraclude. Empty stomach for hep B that fail lamivudime
and adefovir- se: peripheral edema, nephrotoxic
◉ Ribavirin.
Answer: Copegus. W/ food bid for hep c, hepatotoxic, hemolytic
anemia, preg x, psych disorders, ci: renal disfxn
◉ Glipizide.
Answer: Glucotrol 30 min before break & dinner
,◉ Glimeprimide.
Answer: Amaryl 1-2 mg qd w/ 1st meal
◉ Glyburide.
Answer: Diabeta, + metformin = glucovance, do not use w/ renal
failure 2.5-5mg qd
◉ Rosiglitazone.
Answer: Avandia 4-8mg qd (tzd, exacerbate hf, liver damage,
increases hdl, decreases tg/total cholesterol) similar: pioglitazone
(actos)
◉ Repaglinide.
Answer: Prandin 0.5-2mg TID 15-30 min before a meal,
hypoglycemia- do not take with su's
◉ Nateglinide.
Answer: Starlix injection- 15-30 min before meals
◉ Acarbose.
Answer: Precose- w/ 1st bite of meal and water
◉ Miglitol.
, Answer: Glyset w/ 1st bite of meal and water
◉ Linagliptan.
Answer: Tradjenta- 5 mg qd in morning with or without food, no
renal adjustment
◉ Saxagliptin.
Answer: OnglyZa 2.5-5mg qd
◉ Canaglifozin.
Answer: Invokana 100mg qd before first meal of day for DM. Se:
female genital mycotic infxn, increased urination, hyperkalemia, can
increase dig levels, ci: renal dx
◉ Exenatide.
Answer: Byetta 30-60 min before am & pm meals,medguide,
pancreatitis, thyroid c-cell carcinoma xr= bydureon
◉ Liraglutide.
Answer: Victoza QD thyroid c-cell carcinoma, more weight loss, less
pancreatitis
◉ Pramlintide.
