CPJE CLINICAL CERTIFICATION
ASSESSMENT FULL QUESTIONS AND
CORRECT ANSWERS GRADED A+
●● HLA b1502
Answer: Test in Asians. Rash for carbamazepine (tegretol), phenytoin
(Dilantin), fos phenytoin (cerebyx)
●● Trastuzumab
Answer: Herceptin, her/Neu- ado-trastuzunab (kadcyla), lapatinib
(tykerb) pertuzumab (perjeta)
●● Hla- b 5701
Answer: Don't give abacavir (ziagen), epzicom, trizivir
●● Not cross reactive a/ opioid allergy
Answer: Fentanyl, meperidine (Demerol), methadone (dolophine),
tramadol (ultram), tapentadol (nucynta)
●● Inducers
Answer: Ps porcs (phenytoin, smoking, phenobarbital, oxcarbazepine,
rifampin, carbamazepine, St. John's wort)
,●● Inhibitors
Answer: Gpacman (grapefruit, pi's, azoles, cimetidine/cyclosporine,
macrolides- erytho/clarithro, amiodarone, non dihydro (dilt, verapamil)
●● If on amiodarone, decrease these drugs by 30-50%
Answer: Digoxin, warfarin, quinidine, procainanide, statins
●● Statins with high risk of inhibition
Answer: Las (lova, atorva, simva)
●● Entecavir
Answer: Baraclude. Empty stomach for hep B that fail lamivudime and
adefovir- se: peripheral edema, nephrotoxic
●● Ribavirin
Answer: Copegus. W/ food bid for hep c, hepatotoxic, hemolytic
anemia, preg x, psych disorders, ci: renal disfxn
●● Glipizide
Answer: Glucotrol 30 min before break & dinner
●● Glimeprimide
Answer: Amaryl 1-2 mg qd w/ 1st meal
,●● Glyburide
Answer: Diabeta, + metformin = glucovance, do not use w/ renal failure
2.5-5mg qd
●● Rosiglitazone
Answer: Avandia 4-8mg qd (tzd, exacerbate hf, liver damage, increases
hdl, decreases tg/total cholesterol) similar: pioglitazone (actos)
●● Repaglinide
Answer: Prandin 0.5-2mg TID 15-30 min before a meal, hypoglycemia-
do not take with su's
●● Nateglinide
Answer: Starlix injection- 15-30 min before meals
●● Acarbose
Answer: Precose- w/ 1st bite of meal and water
●● Miglitol
Answer: Glyset w/ 1st bite of meal and water
●● Linagliptan
, Answer: Tradjenta- 5 mg qd in morning with or without food, no renal
adjustment
●● Saxagliptin
Answer: OnglyZa 2.5-5mg qd
●● Canaglifozin
Answer: Invokana 100mg qd before first meal of day for DM. Se:
female genital mycotic infxn, increased urination, hyperkalemia, can
increase dig levels, ci: renal dx
●● Exenatide
Answer: Byetta 30-60 min before am & pm meals,medguide,
pancreatitis, thyroid c-cell carcinoma xr= bydureon
●● Liraglutide
Answer: Victoza QD thyroid c-cell carcinoma, more weight loss, less
pancreatitis
●● Pramlintide
Answer: Symlin - injection, skip if no meals, weight loss
●● Insulin aspart
ASSESSMENT FULL QUESTIONS AND
CORRECT ANSWERS GRADED A+
●● HLA b1502
Answer: Test in Asians. Rash for carbamazepine (tegretol), phenytoin
(Dilantin), fos phenytoin (cerebyx)
●● Trastuzumab
Answer: Herceptin, her/Neu- ado-trastuzunab (kadcyla), lapatinib
(tykerb) pertuzumab (perjeta)
●● Hla- b 5701
Answer: Don't give abacavir (ziagen), epzicom, trizivir
●● Not cross reactive a/ opioid allergy
Answer: Fentanyl, meperidine (Demerol), methadone (dolophine),
tramadol (ultram), tapentadol (nucynta)
●● Inducers
Answer: Ps porcs (phenytoin, smoking, phenobarbital, oxcarbazepine,
rifampin, carbamazepine, St. John's wort)
,●● Inhibitors
Answer: Gpacman (grapefruit, pi's, azoles, cimetidine/cyclosporine,
macrolides- erytho/clarithro, amiodarone, non dihydro (dilt, verapamil)
●● If on amiodarone, decrease these drugs by 30-50%
Answer: Digoxin, warfarin, quinidine, procainanide, statins
●● Statins with high risk of inhibition
Answer: Las (lova, atorva, simva)
●● Entecavir
Answer: Baraclude. Empty stomach for hep B that fail lamivudime and
adefovir- se: peripheral edema, nephrotoxic
●● Ribavirin
Answer: Copegus. W/ food bid for hep c, hepatotoxic, hemolytic
anemia, preg x, psych disorders, ci: renal disfxn
●● Glipizide
Answer: Glucotrol 30 min before break & dinner
●● Glimeprimide
Answer: Amaryl 1-2 mg qd w/ 1st meal
,●● Glyburide
Answer: Diabeta, + metformin = glucovance, do not use w/ renal failure
2.5-5mg qd
●● Rosiglitazone
Answer: Avandia 4-8mg qd (tzd, exacerbate hf, liver damage, increases
hdl, decreases tg/total cholesterol) similar: pioglitazone (actos)
●● Repaglinide
Answer: Prandin 0.5-2mg TID 15-30 min before a meal, hypoglycemia-
do not take with su's
●● Nateglinide
Answer: Starlix injection- 15-30 min before meals
●● Acarbose
Answer: Precose- w/ 1st bite of meal and water
●● Miglitol
Answer: Glyset w/ 1st bite of meal and water
●● Linagliptan
, Answer: Tradjenta- 5 mg qd in morning with or without food, no renal
adjustment
●● Saxagliptin
Answer: OnglyZa 2.5-5mg qd
●● Canaglifozin
Answer: Invokana 100mg qd before first meal of day for DM. Se:
female genital mycotic infxn, increased urination, hyperkalemia, can
increase dig levels, ci: renal dx
●● Exenatide
Answer: Byetta 30-60 min before am & pm meals,medguide,
pancreatitis, thyroid c-cell carcinoma xr= bydureon
●● Liraglutide
Answer: Victoza QD thyroid c-cell carcinoma, more weight loss, less
pancreatitis
●● Pramlintide
Answer: Symlin - injection, skip if no meals, weight loss
●● Insulin aspart
