APEA 3P Exam Practice Questions and Answers

APEA 3P (PREDICTIVE, PREVENTIVE,
PERSONALIZED): COMPREHENSIVE
REVIEW OF DIFFERENTIAL DIAGNOSIS
AND CLINICAL PRESENTATION|
LATEST EXAM QUESTIONS AND
ANSWERS


1) Question: A 48-year-old female presents with symmetric joint pain
and swelling in her hands and wrists. Morning stiffness lasts more
than one hour. Physical exam reveals swollen, tender MCP and PIP
joints bilaterally.
What is the most likely diagnosis?** Answer: Rheumatoid arthritis

2) Question: A 60-year-old male presents with severe headache, jaw
pain when chewing, and blurred vision. ESR is markedly elevated.
What is the most
likely diagnosis? Answer: Temporal arteritis (Giant cell arteritis)

3) Question: A 32-year-old female presents with recurrent oral and
genital ulcers, uveitis, and skin lesions.
What is the most likely diagnosis? Answer: Behçet's disease

,4) Question: A 25 old male presents with acute onset of testicular pain
and swelling. He denies dysuria or urethral discharge. Cremasteric
reflex is absent on the affected side. What is the most likely
diagnosis? Answer: Testicular torsion

5) Question: A 22-year-old sexually active female presents with pelvic
pain, fever, chills, and cervical motion tenderness on bimanual exam.
What is the most likely diagnosis?
Answer: Pelvic inflammatory disease (PID)

6) Question: A 50-year-old female presents with episodic vertigo,
tinnitus, and hearing loss in the right ear. What is the most likely
diagnosis? Answer: Ménière's disease

7) Question: A 30-year-old male presents with acute onset of vertigo
without hearing loss following a viral upper respiratory infection.
Symptoms are severe but resolve over several days. What is the most
likely diagnosis?
Answer: Vestibular neuritis (Labyrinthitis)

8) Question: A 40-year-old female presents with recurrent, severe
unilateral headaches lasting 4-72 hours. Headaches are throbbing,
associated with

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nausea, photophobia, and phonophobia. What is the most likely diagnosis?
Answer: Migraine without aura

9) Question: A 55-year-old male presents with severe, unilateral orbital
pain associated with ipsilateral lacrimation, rhinorrhea, and facial
flushing. Episodes last 15-180 minutes and occur multiple times daily
for several weeks. What is the most likely diagnosis? Answer:
Cluster headache

10) Question: A 75-year-old male presents with asymmetric, progressive
tremor at rest, bradykinesia, rigidity, and postural instability. What is
the most likely diagnosis?
Answer: Parkinson's disease

11) Question: A 65-year-old female presents with progressive memory
loss, difficulty with familiar tasks, disorientation, and personality
changes. What is the most likely diagnosis?
Answer: Alzheimer's disease

12) Question: A 32-year-old female presents with episodes of
palpitations, diaphoresis, tremors, and anxiety that resolve after
eating. Symptoms occur several hours after meals. What is the most
likely diagnosis?
Answer: Reactive hypoglycemia
13) Question: A 58 old male with history of GERD presents with
progressive dysphagia, first to solids then to liquids, and unintentional
weight loss. What is the most likely diagnosis?
Answer: Esophageal cancer

14) Question: A 45-year-old female presents with episodic chest pain
described as a squeezing sensation behind the sternum, not related to
exertion, and associated with regurgitation of sourtasting fluid. What
is the most likely diagnosis? Answer: Gastroesophageal reflux
disease (GERD)

15) Question: A 35-year-old female presents with episodic right upper
quadrant pain after eating fatty meals. Ultrasound reveals gallstones.
What is the most likely diagnosis?
Answer: Cholelithiasis (Gallstones)

16) Question: A 50-year-old male with history of alcohol abuse presents
with acute onset of severe epigastric pain radiating to the back,


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nausea, and vomiting. Amylase and lipase are elevated. What is the
most likely diagnosis? Answer: Acute pancreatitis
17) Question: A 60-year-old female presents with right upper quadrant
pain, fever, and jaundice. What is this triad known as?
Answer: Charcot's triad (suggests ascending cholangitis)




18) Question: A 52-year-old male presents with acute onset of severe
right flank pain radiating to the groin. He is restless and unable to find
a comfortable position. Vital signs are stable. Urinalysis reveals
hematuria. What is the most likely diagnosis?
Answer: Nephrolithiasis (Kidney stone)

19) Question: A 68-year-old female with a history of hypertension and
type 2 diabetes presents with sudden onset of painless vision loss in
the right eye. She describes it as a "curtain coming down" over her
vision. What is the most likely diagnosis?
Answer: Retinal artery occlusion (Amaurosis fugax)

20) Question: A 45-year-old male presents with a painful, swollen left
great toe that started suddenly last night. He denies trauma. He has a
history of hypertension treated with hydrochlorothiazide. What is the
most likely diagnosis?
Answer: Acute gouty arthritis

21) Question: A 72-year-old male presents with progressive difficulty
urinating, weak stream, hesitancy, and sensation of incomplete
bladder emptying. Digital rectal exam reveals an enlarged, smooth,
non-tender prostate. What is the most likely diagnosis?
Answer: Benign prostatic hyperplasia (BPH)

22) Question: A 35-year-old female presents with fatigue, weight gain,
cold intolerance, constipation, and dry skin. Physical exam reveals