HESI PHARMACOLOGY EXAM QUESTIONS & ANSWERS 2026-2027 | EXAM
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
HESI Pharmacology Exam
Questions & Answers 2026-
2027 |
Verified Answers Exam Ready With Rationales
67 QUESTIONS
DOCUMENT OVERVIEW
This HESI Pharmacology Exam Questions & Answers document provides 67 questions with their correct
answers, covering essential nursing pharmacology concepts. It is a valuable resource for students to review
and prepare for certification exams. The questions and answers directly align with common pharmacology
topics encountered in nursing education.
CONTENTS
01 Gastrointestinal & Endocrine Agents Q1–Q10
02 Psychiatric & Neuromuscular Agents Q11–Q18
03 Respiratory & Anti-inflammatory Agents Q19–Q25
04 Renal & Fluid Balance Q26–Q30
05 General Pharmacology Principles Q31–Q37
Page 1
, 06 Neurology & Pain Management Q38–Q46
07 Immunology & Anti-infectives Q47–Q57
08 Cardiovascular & Anticoagulant Therapy Q58–Q67
E XA M Q U EST I O N S
Q1 QUESTION 1 OF 67
A client receives a prescription for esomeprazole (Nexium) for heartburn. Which finding in the client's history
should the nurse report to the healthcare provider before administering the prescription?
Eats spicy food three times a week.
History of deep vein thrombosis.
Drinks 2 alcoholic beverages on weekends.
Family history of diabetes mellitus.
CORRECT ANSWER
History of deep vein thrombosis.
Q2 QUESTION 2 OF 67
The therapeutic effect of insulin in treating Type 1 diabetes mellitus is based on which physiologic action?
Facilitates transport of glucose into the cells.
Stimulates function of beta cells in the pancreas.
Increases intracellular receptor site sensitivity.
Delays carbohydrate digestion and absorption.
CORRECT ANSWER
Facilitates transport of glucose into the cells.
Q3 QUESTION 3 OF 67
What is the expected outcome of esomeprazole (Nexium) when prescribed for a client with
gastroesophageal reflux disease (GERD)?
Promotion of rapid tissue healing.
Increased gastric emptying.
Page 2
, Improved esophageal peristalsis.
Neutralization of gastric secretions.
CORRECT ANSWER
Promotion of rapid tissue healing.
Q4 QUESTION 4 OF 67
A client is taking sulfisoxazole (Gantrisin) for a urinary tract infection (UTI) and complains of nausea and
gastric upset since starting the medication. Which additional adverse reaction should the nurse instruct the
client to report?
Rash.
Diarrhea.
Hematuria.
Muscle cramping.
CORRECT ANSWER
Rash.
Q5 QUESTION 5 OF 67
The nurse should expect the healthcare provider to prescribed what treatment regimen for a client with
peptic ulcer caused by Helicobacter pylori ? (Select all that apply.)
Select all that apply
Clarithromycin (Biaxin).
Sulfisoxazole (Gantrisin).
Misoprostol (Cytotec).
Omeprazole (Prilosec).
Metronidazole (Flagyl).
Sucralfate (Carafate).
CORRECT ANSWER
Clarithromycin (Biaxin).
Omeprazole (Prilosec).
Metronidazole (Flagyl).
Q6 QUESTION 6 OF 67
Page 3
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
HESI Pharmacology Exam
Questions & Answers 2026-
2027 |
Verified Answers Exam Ready With Rationales
67 QUESTIONS
DOCUMENT OVERVIEW
This HESI Pharmacology Exam Questions & Answers document provides 67 questions with their correct
answers, covering essential nursing pharmacology concepts. It is a valuable resource for students to review
and prepare for certification exams. The questions and answers directly align with common pharmacology
topics encountered in nursing education.
CONTENTS
01 Gastrointestinal & Endocrine Agents Q1–Q10
02 Psychiatric & Neuromuscular Agents Q11–Q18
03 Respiratory & Anti-inflammatory Agents Q19–Q25
04 Renal & Fluid Balance Q26–Q30
05 General Pharmacology Principles Q31–Q37
Page 1
, 06 Neurology & Pain Management Q38–Q46
07 Immunology & Anti-infectives Q47–Q57
08 Cardiovascular & Anticoagulant Therapy Q58–Q67
E XA M Q U EST I O N S
Q1 QUESTION 1 OF 67
A client receives a prescription for esomeprazole (Nexium) for heartburn. Which finding in the client's history
should the nurse report to the healthcare provider before administering the prescription?
Eats spicy food three times a week.
History of deep vein thrombosis.
Drinks 2 alcoholic beverages on weekends.
Family history of diabetes mellitus.
CORRECT ANSWER
History of deep vein thrombosis.
Q2 QUESTION 2 OF 67
The therapeutic effect of insulin in treating Type 1 diabetes mellitus is based on which physiologic action?
Facilitates transport of glucose into the cells.
Stimulates function of beta cells in the pancreas.
Increases intracellular receptor site sensitivity.
Delays carbohydrate digestion and absorption.
CORRECT ANSWER
Facilitates transport of glucose into the cells.
Q3 QUESTION 3 OF 67
What is the expected outcome of esomeprazole (Nexium) when prescribed for a client with
gastroesophageal reflux disease (GERD)?
Promotion of rapid tissue healing.
Increased gastric emptying.
Page 2
, Improved esophageal peristalsis.
Neutralization of gastric secretions.
CORRECT ANSWER
Promotion of rapid tissue healing.
Q4 QUESTION 4 OF 67
A client is taking sulfisoxazole (Gantrisin) for a urinary tract infection (UTI) and complains of nausea and
gastric upset since starting the medication. Which additional adverse reaction should the nurse instruct the
client to report?
Rash.
Diarrhea.
Hematuria.
Muscle cramping.
CORRECT ANSWER
Rash.
Q5 QUESTION 5 OF 67
The nurse should expect the healthcare provider to prescribed what treatment regimen for a client with
peptic ulcer caused by Helicobacter pylori ? (Select all that apply.)
Select all that apply
Clarithromycin (Biaxin).
Sulfisoxazole (Gantrisin).
Misoprostol (Cytotec).
Omeprazole (Prilosec).
Metronidazole (Flagyl).
Sucralfate (Carafate).
CORRECT ANSWER
Clarithromycin (Biaxin).
Omeprazole (Prilosec).
Metronidazole (Flagyl).
Q6 QUESTION 6 OF 67
Page 3
