WGU D115 PATHOPHYSIOLOGY OBJECTIVE ASSESSMENT (OA) EXAM QUESTIONS & ANSWER… EXAM
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
WGU D115 Pathophysiology
Objective Assessment (OA)
Exam Questions & Answers
2026-2027
Verified Answers Exam Ready With Rationales
107 QUESTIONS
DOCUMENT OVERVIEW
This document provides 107 questions with their correct answers, covering core pathophysiology concepts.
It is a valuable resource for understanding human disease processes. Students can utilize this compilation
for comprehensive study and review, directly preparing for certification assessments.
CONTENTS
01 02 03
• Genetic and Chromosomal Disorders • Endocrine and Metabolic Disorders • Infectious Diseases and Inflammatory Co
04 • Hematologic Disorders 05 06
• Musculoskeletal and Connective Tissue• Cardiovascular
Disorders and Circulatory System
07 08 09
• General Pathophysiology Concepts • Respiratory System Disorders • Gastrointestinal and Urinary System Diso
10
• Neurological Disorders and Cranial Nerves
Page 1
, E XA M Q U EST I O N S
Q1 QUESTION 1 OF 107
Turner Syndrome
CORRECT ANSWER
A chromosomal disorder in females in which either an X chromosome is missing, making the person XO instead of XX, or part of
one X chromosome is deleted.
Q2 QUESTION 2 OF 107
Tay-Sachs disease
CORRECT ANSWER
A human genetic disease caused by a recessive allele that leads to the accumulation of certain lipids in the brain. Seizures,
blindness, and degeneration of motor and mental performance usually become manifest a few months after birth.
Q3 QUESTION 3 OF 107
Down Syndrome
CORRECT ANSWER
a condition of mild to severe intellectual disability and associated physical disorders caused by an extra copy of chromosome 21
Q4 QUESTION 4 OF 107
Marfan Syndrome
CORRECT ANSWER
autosomal dominant trait..
a genetic disorder that changes the proteins that help make healthy connective tissue. This leads to problems with the
development of connective tissue, which supports the bones, muscles, organs, and tissues in your body.
Q5 QUESTION 5 OF 107
Page 2
, Marfans syndrome genetic trait type
CORRECT ANSWER
Autosomal dominant. inherited in an autosomal pattern which means one copy of the altered gene in each cell is sufficient to
cause the disorder.
Q6 QUESTION 6 OF 107
What causes Marfan's syndrome?
CORRECT ANSWER
Defects or deletions (pathogenic variants) of the fibrillin-1 (FBN1) gene have been shown to cause Marfans syndrome
at least 25% of Marfan syndrome cases result from a new mutation in the FBN1 gene
Q7 QUESTION 7 OF 107
spina bifida
CORRECT ANSWER
a congenital defect that occurs during early pregnancy when the spinal canal fails to close completely around the spinal cord to
protect it
Q8 QUESTION 8 OF 107
What can cause Spina Bifida
CORRECT ANSWER
Decreased folic acid or maternal use of valproic acid
Q9 QUESTION 9 OF 107
Turner syndrome characteristics
CORRECT ANSWER
Underdeveloped ovaries (sterile)
Short stature (~ 4'7")
Webbing of the neck
Edema
Underdeveloped breasts; wide nipples
High number of aborted fetuses
Page 3
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
WGU D115 Pathophysiology
Objective Assessment (OA)
Exam Questions & Answers
2026-2027
Verified Answers Exam Ready With Rationales
107 QUESTIONS
DOCUMENT OVERVIEW
This document provides 107 questions with their correct answers, covering core pathophysiology concepts.
It is a valuable resource for understanding human disease processes. Students can utilize this compilation
for comprehensive study and review, directly preparing for certification assessments.
CONTENTS
01 02 03
• Genetic and Chromosomal Disorders • Endocrine and Metabolic Disorders • Infectious Diseases and Inflammatory Co
04 • Hematologic Disorders 05 06
• Musculoskeletal and Connective Tissue• Cardiovascular
Disorders and Circulatory System
07 08 09
• General Pathophysiology Concepts • Respiratory System Disorders • Gastrointestinal and Urinary System Diso
10
• Neurological Disorders and Cranial Nerves
Page 1
, E XA M Q U EST I O N S
Q1 QUESTION 1 OF 107
Turner Syndrome
CORRECT ANSWER
A chromosomal disorder in females in which either an X chromosome is missing, making the person XO instead of XX, or part of
one X chromosome is deleted.
Q2 QUESTION 2 OF 107
Tay-Sachs disease
CORRECT ANSWER
A human genetic disease caused by a recessive allele that leads to the accumulation of certain lipids in the brain. Seizures,
blindness, and degeneration of motor and mental performance usually become manifest a few months after birth.
Q3 QUESTION 3 OF 107
Down Syndrome
CORRECT ANSWER
a condition of mild to severe intellectual disability and associated physical disorders caused by an extra copy of chromosome 21
Q4 QUESTION 4 OF 107
Marfan Syndrome
CORRECT ANSWER
autosomal dominant trait..
a genetic disorder that changes the proteins that help make healthy connective tissue. This leads to problems with the
development of connective tissue, which supports the bones, muscles, organs, and tissues in your body.
Q5 QUESTION 5 OF 107
Page 2
, Marfans syndrome genetic trait type
CORRECT ANSWER
Autosomal dominant. inherited in an autosomal pattern which means one copy of the altered gene in each cell is sufficient to
cause the disorder.
Q6 QUESTION 6 OF 107
What causes Marfan's syndrome?
CORRECT ANSWER
Defects or deletions (pathogenic variants) of the fibrillin-1 (FBN1) gene have been shown to cause Marfans syndrome
at least 25% of Marfan syndrome cases result from a new mutation in the FBN1 gene
Q7 QUESTION 7 OF 107
spina bifida
CORRECT ANSWER
a congenital defect that occurs during early pregnancy when the spinal canal fails to close completely around the spinal cord to
protect it
Q8 QUESTION 8 OF 107
What can cause Spina Bifida
CORRECT ANSWER
Decreased folic acid or maternal use of valproic acid
Q9 QUESTION 9 OF 107
Turner syndrome characteristics
CORRECT ANSWER
Underdeveloped ovaries (sterile)
Short stature (~ 4'7")
Webbing of the neck
Edema
Underdeveloped breasts; wide nipples
High number of aborted fetuses
Page 3
