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EXAM OVERVIEW
The ANCC Family Nurse Practitioner certification exam is predominantly non-clinical,
covering leadership, management, risk management, ethics, healthcare policy, research,
and professional practice domains . This comprehensive review focuses on the non-
clinical content areas that comprise a significant portion of the exam.
DOMAIN 1: RESEARCH AND STATISTICS (Questions 1-50)
1. Which statistical test compares one variable, such as blood pressure, between
two groups?
A. P-value
B. T-test
C. Standard deviation
D. Confidence interval
Answer: B
Rationale: A t-test compares the means of one variable between two different groups .
It is used to determine if there is a statistically significant difference between the groups.
2. What does a p-value represent in research?
A. The measure of spread or dispersion of data
B. The probability of error involved in accepting observed results
C. The reliability of an estimate
,D. The strength of correlation between variables
Answer: B
Rationale: The p-value represents the probability of error involved in accepting the
observed results as a valid representative of the population . A p-value <0.05 is typically
considered statistically significant.
3. Which of the following is the measure of the spread or dispersion of a set of
data from the average?
A. P-value
B. T-test
C. Standard deviation
D. Confidence interval
Answer: C
Rationale: Standard deviation measures the spread or dispersion of a set of data from
the average . A low standard deviation indicates data points tend to be close to the
mean.
4. What does a confidence interval measure?
A. The probability of error in research findings
B. The reliability of an estimate with defined limits
C. The difference between two groups
D. The correlation between variables
Answer: B
Rationale: A confidence interval measures the reliability of an estimate, specifying the
probability of including the parameter being estimated . A 95% confidence interval
indicates 95% certainty that the true value lies within the range.
,5. Which research design follows individuals with a particular condition over a
period of time?
A. Randomized controlled trial
B. Cross-sectional study
C. Cohort study
D. Case report
Answer: C
Rationale: A cohort study follows individuals with a particular condition over a period of
time and is the best design to obtain valid information about the prognosis of a
condition .
6. Which study design is considered the best to determine the benefits and risks of
an intervention?
A. Cohort study
B. Cross-sectional study
C. Randomized controlled trial
D. Case report
Answer: C
Rationale: The randomized controlled trial (RCT) is the best design to determine the
benefits and risks of an intervention . It provides the highest level of evidence for
causation.
7. Which study design is best for evaluating a diagnostic test?
A. Cohort study
B. Cross-sectional study
C. Randomized controlled trial
D. Qualitative research
, Answer: B
Rationale: A cross-sectional study is best designed to evaluate a diagnostic test . It
assesses the test's performance at a single point in time.
8. Which type of research explores phenomena through descriptions of people and
events?
A. Quantitative research
B. Qualitative research
C. Experimental research
D. Quasi-experimental research
Answer: B
Rationale: Qualitative research explores phenomena through descriptions of people
and events . It includes case studies, field studies, participant observation, and
ethnographic studies.
9. In which type of research can the researcher NOT control, manipulate, or alter
the predictor variable or subjects?
A. Experimental research
B. Quasi-experimental research
C. Non-experimental research
D. Randomized controlled trial
Answer: C
Rationale: In non-experimental research, the researcher cannot control, manipulate, or
alter the predictor variable or subjects . It relies on interpretation, observation, or
interactions to arrive at a conclusion.
10. Which type of research involves random sampling and random assignment of
subjects?