NRNP 6675 FINAL EXAM QUESTIONS & ANSWERS 2026-2027 | WALDEN UNIVERSITY … EXAM
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
NRNP 6675 Final Exam
Questions & Answers 2026-
2027 | Walden University |
Comprehensive Edition
(Rationales)
Verified Answers Exam Ready With Rationales
455 QUESTIONS
DOCUMENT OVERVIEW
This comprehensive document provides 455 verified questions with correct answers and detailed rationales
covering advanced psychopharmacology. It is an invaluable resource for students to study, review complex
concepts, and prepare for certification exams in psychiatric-mental health nursing. The format directly
supports learning by offering explanations for each question-answer pair.
CONTENTS
01 • All Questions
Page 1
, E XA M Q U EST I O N S
Q1 QUESTION 1 OF 455
Which of the following are risk factors for neuroleptic malignant syndrome? Select all that apply
CORRECT ANSWER
Rapid dose escalation; parental route of administration; higher potency typical antipsychotics
RATIONALE
Rapid dose escalation, parenteral administration, and higher potency typical antipsychotics increase the risk of neuroleptic
malignant syndrome due to accelerated dopaminergic blockade and central thermoregulatory dysfunction. This highlights
the importance of gradual titration and route of administration in managing antipsychotic therapy to mitigate this potentially
fatal reaction.
Q2 QUESTION 2 OF 455
Discrepancy between anatomical sex and gender is known as?
CORRECT ANSWER
B) Gender Discordance
RATIONALE
Gender discordance describes the incongruence between an individual's anatomical sex assigned at birth and their internal
sense of gender identity. This distinction is key to understanding gender dysphoria and related concepts.
Q3 QUESTION 3 OF 455
Antipsychotic medication provides D2 blockage in the meso-coritcal pathway causing which of the following
effects?
CORRECT ANSWER
B) Increases EPS
Incorrect: reduces negative s/s, causes prolactinemia, reduces positive symptoms
Page 2
, RATIONALE
Dopamine D2 receptor blockade in the nigrostriatal pathway, not the mesocortical pathway, leads to extrapyramidal
symptoms (EPS). Mesocortical D2 blockade, conversely, is associated with a *reduction* in negative symptoms.
Q4 QUESTION 4 OF 455
Phencyclidine (PCP) and ketamine exert their unique behavioral effects by blocking which of the following receptors?
CORRECT ANSWER
D) NMDA type receptors
Incorrect: GABA, serotonin, dopamine "receptors"
RATIONALE
Phencyclidine and ketamine are dissociative anesthetics that produce their characteristic psychotomimetic effects by acting
as non-competitive antagonists at the NMDA receptor, thereby disrupting glutamatergic neurotransmission. This blockade
of NMDA receptors is the primary mechanism underlying their profound alterations in perception, cognition, and behavior.
Q5 QUESTION 5 OF 455
The diagnosis used to describe a syndrome characterized by specific s/s resulting from recent ingestion or exposure
to a substance is known as which of the folllowing?
CORRECT ANSWER
C) Substance use disorder
Incorrect: substance intox, substance withdrawal, all of the above
RATIONALE
Substance use disorder encompasses the broad spectrum of maladaptive behaviors arising from substance ingestion,
including intoxication and withdrawal. This diagnosis reflects the complex interplay of physiological and psychological
dependence on a substance.
Q6 QUESTION 6 OF 455
Abnormal involuntary movements in a rhythmic pattern affecting the face, mouth, tongue jaw is known as which of
the following?
CORRECT ANSWER
C) Tardive dyskinesia
Incorrect: akathisia, dystonia, EPS
Page 3
, RATIONALE
Tardive dyskinesia is characterized by involuntary, repetitive, rhythmic movements, particularly of the orofacial muscles,
which distinguishes it from other extrapyramidal side effects like akathisia (restlessness) or dystonia (sustained muscle
contractions). This specific pattern of movement is the hallmark of tardive dyskinesia, often associated with long-term
antipsychotic use.
Q7 QUESTION 7 OF 455
A deeply held belief despite evidence to the contrary, lasting at least 1 month, without prominent hallucinations, with
functional impairment that relates to the delusional system disorder called?
CORRECT ANSWER
Delusional disorder
RATIONALE
Delusional disorder is characterized by the presence of one or more delusions for at least 1 month without other psychotic
symptoms, and functioning is not markedly impaired outside of the delusion's direct impact. This contrasts with
schizophrenia, which involves more pervasive psychotic symptoms and functional decline.
Q8 QUESTION 8 OF 455
Which of the following is true about preoccupation with castration?
CORRECT ANSWER
A) This can be serious and life threatening if castration is carried out without medical supervision
Incorrect: consistent with transvestiatic disorder, other specified paraphillic disorder, or sexual machochism disorder
RATIONALE
Preoccupation with castration, when acted upon without medical supervision, poses significant risks of severe injury or
death. This highlights the potential for dangerous self-harm stemming from severe paraphilic impulses or obsessive
thoughts.
Q9 QUESTION 9 OF 455
Page 4
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
NRNP 6675 Final Exam
Questions & Answers 2026-
2027 | Walden University |
Comprehensive Edition
(Rationales)
Verified Answers Exam Ready With Rationales
455 QUESTIONS
DOCUMENT OVERVIEW
This comprehensive document provides 455 verified questions with correct answers and detailed rationales
covering advanced psychopharmacology. It is an invaluable resource for students to study, review complex
concepts, and prepare for certification exams in psychiatric-mental health nursing. The format directly
supports learning by offering explanations for each question-answer pair.
CONTENTS
01 • All Questions
Page 1
, E XA M Q U EST I O N S
Q1 QUESTION 1 OF 455
Which of the following are risk factors for neuroleptic malignant syndrome? Select all that apply
CORRECT ANSWER
Rapid dose escalation; parental route of administration; higher potency typical antipsychotics
RATIONALE
Rapid dose escalation, parenteral administration, and higher potency typical antipsychotics increase the risk of neuroleptic
malignant syndrome due to accelerated dopaminergic blockade and central thermoregulatory dysfunction. This highlights
the importance of gradual titration and route of administration in managing antipsychotic therapy to mitigate this potentially
fatal reaction.
Q2 QUESTION 2 OF 455
Discrepancy between anatomical sex and gender is known as?
CORRECT ANSWER
B) Gender Discordance
RATIONALE
Gender discordance describes the incongruence between an individual's anatomical sex assigned at birth and their internal
sense of gender identity. This distinction is key to understanding gender dysphoria and related concepts.
Q3 QUESTION 3 OF 455
Antipsychotic medication provides D2 blockage in the meso-coritcal pathway causing which of the following
effects?
CORRECT ANSWER
B) Increases EPS
Incorrect: reduces negative s/s, causes prolactinemia, reduces positive symptoms
Page 2
, RATIONALE
Dopamine D2 receptor blockade in the nigrostriatal pathway, not the mesocortical pathway, leads to extrapyramidal
symptoms (EPS). Mesocortical D2 blockade, conversely, is associated with a *reduction* in negative symptoms.
Q4 QUESTION 4 OF 455
Phencyclidine (PCP) and ketamine exert their unique behavioral effects by blocking which of the following receptors?
CORRECT ANSWER
D) NMDA type receptors
Incorrect: GABA, serotonin, dopamine "receptors"
RATIONALE
Phencyclidine and ketamine are dissociative anesthetics that produce their characteristic psychotomimetic effects by acting
as non-competitive antagonists at the NMDA receptor, thereby disrupting glutamatergic neurotransmission. This blockade
of NMDA receptors is the primary mechanism underlying their profound alterations in perception, cognition, and behavior.
Q5 QUESTION 5 OF 455
The diagnosis used to describe a syndrome characterized by specific s/s resulting from recent ingestion or exposure
to a substance is known as which of the folllowing?
CORRECT ANSWER
C) Substance use disorder
Incorrect: substance intox, substance withdrawal, all of the above
RATIONALE
Substance use disorder encompasses the broad spectrum of maladaptive behaviors arising from substance ingestion,
including intoxication and withdrawal. This diagnosis reflects the complex interplay of physiological and psychological
dependence on a substance.
Q6 QUESTION 6 OF 455
Abnormal involuntary movements in a rhythmic pattern affecting the face, mouth, tongue jaw is known as which of
the following?
CORRECT ANSWER
C) Tardive dyskinesia
Incorrect: akathisia, dystonia, EPS
Page 3
, RATIONALE
Tardive dyskinesia is characterized by involuntary, repetitive, rhythmic movements, particularly of the orofacial muscles,
which distinguishes it from other extrapyramidal side effects like akathisia (restlessness) or dystonia (sustained muscle
contractions). This specific pattern of movement is the hallmark of tardive dyskinesia, often associated with long-term
antipsychotic use.
Q7 QUESTION 7 OF 455
A deeply held belief despite evidence to the contrary, lasting at least 1 month, without prominent hallucinations, with
functional impairment that relates to the delusional system disorder called?
CORRECT ANSWER
Delusional disorder
RATIONALE
Delusional disorder is characterized by the presence of one or more delusions for at least 1 month without other psychotic
symptoms, and functioning is not markedly impaired outside of the delusion's direct impact. This contrasts with
schizophrenia, which involves more pervasive psychotic symptoms and functional decline.
Q8 QUESTION 8 OF 455
Which of the following is true about preoccupation with castration?
CORRECT ANSWER
A) This can be serious and life threatening if castration is carried out without medical supervision
Incorrect: consistent with transvestiatic disorder, other specified paraphillic disorder, or sexual machochism disorder
RATIONALE
Preoccupation with castration, when acted upon without medical supervision, poses significant risks of severe injury or
death. This highlights the potential for dangerous self-harm stemming from severe paraphilic impulses or obsessive
thoughts.
Q9 QUESTION 9 OF 455
Page 4
