GMS 6551 (FUND MED PHARMA): PROBLEM SET 4 ACTUAL QUESTIONS AND CORRECT ANSWERS

GMS 6551 (FUND MED PHARMA): PROBLEM SET 4 ACTUAL
QUESTIONS AND CORRECT ANSWERS

Through which route is warfarin usually Oral
administered?


Oral
Sublingual
Intravenous
Inhalation
Topical


Through which routes of administration will Oral
at least some first-pass metabolism occur?
Select all that apply. Rectal


Oral
Sublingual
Rectal
Intravenous
Subcutaneous
Intramuscular
Topical
Transdermal
Inhalation


Would you expect aspirin to be absorbed Low pH
better at high or low pH? Hint: Think of the
chemical name for aspirin.


High pH
Low pH


Would you expect a more polar or nonpolar Nonpolar
drug to have more bioavailability?


Polar
Nonpolar


Assuming the same lipophilicity and that all Tylenol
are neutrally charged (in reality these are
horrible assumptions), which drug would
you expect to have the best membrane
permeability?


Tylenol
Ibuprofen
Aspirin
Aleve
Codeine