, NSG 318 Final Exam – Pharmacology Exam – NGN
Questions and Case Scenarios (Guarantee Pass)
Table of Contents
NSG 318 FINAL EXAM
NSG 318 FINAL EXAM STUDY GUIDE
NSG 318 FINAL EXAM
1. Which of the following best defines pharmacology?
• A. The study of how drugs are absorbed, distributed, metabolized, and excreted
by the body
• B. The study of the effects of drugs on the body's physiological processes
• C. The study of medications and their effects on living systems
• D. The study of genetic factors that influence individual drug responses
Answer: C
Rationale: Pharmacology is defined as the study of medications/drugs and the manner
in which the function of living systems is affected by chemical substances.
Pharmacokinetics specifically deals with drug movement through the body,
pharmacodynamics focuses on drug effects, and pharmacogenetics examines genetic
influences .
2. What is the primary purpose of the six rights of medication administration?
• A. To ensure the nurse administers medications within the correct time frame
• B. To prevent medication errors and ensure patient safety
• C. To document all medications given in the electronic health record
, • D. To verify the patient's insurance covers the prescribed medication
Answer: B
Rationale: The six rights (right patient, right drug, right dose, right route, right time,
right documentation) are foundational safety principles designed to prevent medication
errors. Each right serves as a critical checkpoint before medication administration,
protecting patients from potential harm .
3. According to the NSG 318 Final Exam blueprint, the cumulative content covers
which exam topics?
• A. Exam 1 only
• B. Exam 2 only
• C. Exam 3 only
• D. All previous exams cumulatively
Answer: D
Rationale: The Final Exam is cumulative, covering content from all modules: Exam 1
(pharmacokinetics, pharmacodynamics, medication safety), Exam 2 (autonomic/CNS
agents, anti-infectives, cardiovascular drugs), and Exam 3 (anti-inflammatory,
immunomodulators, etc.) .
4. A drug that binds to a receptor and produces a maximal response is called a:
• A. Partial agonist
• B. Antagonist
• C. Full agonist
• D. Inverse agonist
Answer: C
Rationale: A full agonist binds to a receptor and produces the maximum possible
response. A partial agonist produces a submaximal response even at full receptor
occupancy, while an antagonist blocks receptor activation .
, 5. Which of the following best describes the therapeutic index (TI)?
• A. TI = ED₅₀ / TD₅₀
• B. TI = TD₅₀ / ED₅₀
• C. TI = ED₉₉ / LD₁
• D. TI = LD₁ / ED₉₉
Answer: B
Rationale: The therapeutic index is the ratio of the toxic dose (TD₅₀) to the effective
dose (ED₅₀). A larger TI indicates a wider margin of safety, meaning there is a greater
separation between therapeutic and toxic doses .
6. A drug with a narrow therapeutic index:
• A. Has a wide margin of safety
• B. Requires careful monitoring of serum drug levels
• C. Is safe for over-the-counter use
• D. Cannot cause toxicity even at high doses
Answer: B
Rationale: Drugs with a narrow therapeutic index have a small margin between
therapeutic and toxic doses. Examples include digoxin and warfarin, which require
careful monitoring of serum drug levels to prevent toxicity .
7. Bioavailability is defined as:
• A. The fraction of an administered dose that reaches systemic circulation
unchanged
• B. The time required for a drug to reach its peak concentration
• C. The percentage of drug that binds to plasma proteins
Questions and Case Scenarios (Guarantee Pass)
Table of Contents
NSG 318 FINAL EXAM
NSG 318 FINAL EXAM STUDY GUIDE
NSG 318 FINAL EXAM
1. Which of the following best defines pharmacology?
• A. The study of how drugs are absorbed, distributed, metabolized, and excreted
by the body
• B. The study of the effects of drugs on the body's physiological processes
• C. The study of medications and their effects on living systems
• D. The study of genetic factors that influence individual drug responses
Answer: C
Rationale: Pharmacology is defined as the study of medications/drugs and the manner
in which the function of living systems is affected by chemical substances.
Pharmacokinetics specifically deals with drug movement through the body,
pharmacodynamics focuses on drug effects, and pharmacogenetics examines genetic
influences .
2. What is the primary purpose of the six rights of medication administration?
• A. To ensure the nurse administers medications within the correct time frame
• B. To prevent medication errors and ensure patient safety
• C. To document all medications given in the electronic health record
, • D. To verify the patient's insurance covers the prescribed medication
Answer: B
Rationale: The six rights (right patient, right drug, right dose, right route, right time,
right documentation) are foundational safety principles designed to prevent medication
errors. Each right serves as a critical checkpoint before medication administration,
protecting patients from potential harm .
3. According to the NSG 318 Final Exam blueprint, the cumulative content covers
which exam topics?
• A. Exam 1 only
• B. Exam 2 only
• C. Exam 3 only
• D. All previous exams cumulatively
Answer: D
Rationale: The Final Exam is cumulative, covering content from all modules: Exam 1
(pharmacokinetics, pharmacodynamics, medication safety), Exam 2 (autonomic/CNS
agents, anti-infectives, cardiovascular drugs), and Exam 3 (anti-inflammatory,
immunomodulators, etc.) .
4. A drug that binds to a receptor and produces a maximal response is called a:
• A. Partial agonist
• B. Antagonist
• C. Full agonist
• D. Inverse agonist
Answer: C
Rationale: A full agonist binds to a receptor and produces the maximum possible
response. A partial agonist produces a submaximal response even at full receptor
occupancy, while an antagonist blocks receptor activation .
, 5. Which of the following best describes the therapeutic index (TI)?
• A. TI = ED₅₀ / TD₅₀
• B. TI = TD₅₀ / ED₅₀
• C. TI = ED₉₉ / LD₁
• D. TI = LD₁ / ED₉₉
Answer: B
Rationale: The therapeutic index is the ratio of the toxic dose (TD₅₀) to the effective
dose (ED₅₀). A larger TI indicates a wider margin of safety, meaning there is a greater
separation between therapeutic and toxic doses .
6. A drug with a narrow therapeutic index:
• A. Has a wide margin of safety
• B. Requires careful monitoring of serum drug levels
• C. Is safe for over-the-counter use
• D. Cannot cause toxicity even at high doses
Answer: B
Rationale: Drugs with a narrow therapeutic index have a small margin between
therapeutic and toxic doses. Examples include digoxin and warfarin, which require
careful monitoring of serum drug levels to prevent toxicity .
7. Bioavailability is defined as:
• A. The fraction of an administered dose that reaches systemic circulation
unchanged
• B. The time required for a drug to reach its peak concentration
• C. The percentage of drug that binds to plasma proteins
