NURS 6501 Advanced Pathophysiology
Exam Week 1 Genetic, Cellular Biology &
Tissue Walden University Questions and
Answers
1. acrocentric: refers to the terminal location of centromere on chromosomes 13, 14, 15, 21,
and 22
2. allelic heterogeneity: the situation in which multiple alleles at a single locus can
produce one or more disease phenotypes.
3. amorphic: refers to mutations that cause a complete loss of function for the respective
1/
1
, gene, and therefore yield the same phenotype as a complete gene deletion.
4. aneuploidy: a general term used to denote any unbalanced chromosome complement
5. antimorphic: refers to mutations that when present in heterozygous form opposite a
nonmutant allele will result in a phenotype similar to homozygous for loss of function alleles.
6. ascertainment bias: the situation in which individuals or families in a genetic study are not
representative of the general population because of the way in which they are identified
7. autosomal: located on chromosomes 1-22 rather than x or y
1/
1
Exam Week 1 Genetic, Cellular Biology &
Tissue Walden University Questions and
Answers
1. acrocentric: refers to the terminal location of centromere on chromosomes 13, 14, 15, 21,
and 22
2. allelic heterogeneity: the situation in which multiple alleles at a single locus can
produce one or more disease phenotypes.
3. amorphic: refers to mutations that cause a complete loss of function for the respective
1/
1
, gene, and therefore yield the same phenotype as a complete gene deletion.
4. aneuploidy: a general term used to denote any unbalanced chromosome complement
5. antimorphic: refers to mutations that when present in heterozygous form opposite a
nonmutant allele will result in a phenotype similar to homozygous for loss of function alleles.
6. ascertainment bias: the situation in which individuals or families in a genetic study are not
representative of the general population because of the way in which they are identified
7. autosomal: located on chromosomes 1-22 rather than x or y
1/
1
