Advanced Pharmacology Final Exam
Review with questions and well
verified answers actual exam!!!
2026
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - ANSWER -
Aldosterone antagonist
Heparin exerts its therapeutic action by what? - ANSWER -Upregulating the activity of
one of the body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an
anaphylactic reaction. - ANSWER -Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - ANSWER -Photo-therapy and topical
corticosteroids
What is the first choice of drug therapy for the majority of patients with uncomplicated stage I
hypertension? - ANSWER -Thiazide diuretics
What is the effect of cardiac glycosides? - ANSWER -Digitalis glycosides have a negative
chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
ANSWER -Medroxyprogesterone (Depo-Provera)
, What is an anti-hypertensive agent which competes with epinephrine for available beta-
receptor sites? - ANSWER -Atenolol (Tenormin)
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin
therapy? - ANSWER -To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - ANSWER -
Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level with? -
ANSWER -Propanolol (Inderal)
What type of action does nitrates have on the body? - ANSWER -Reduction in systemic
venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with
known coronary artery disease? - ANSWER -100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - ANSWER -Depressing phase 4
depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones
and re-establish eumetabolic state in a patient with Graves' disease? - ANSWER -Anti-
thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal
insufficiency? - ANSWER -Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart
failure? - ANSWER -Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? -
ANSWER -Methyldopa (Aldomet)
Review with questions and well
verified answers actual exam!!!
2026
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - ANSWER -
Aldosterone antagonist
Heparin exerts its therapeutic action by what? - ANSWER -Upregulating the activity of
one of the body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an
anaphylactic reaction. - ANSWER -Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - ANSWER -Photo-therapy and topical
corticosteroids
What is the first choice of drug therapy for the majority of patients with uncomplicated stage I
hypertension? - ANSWER -Thiazide diuretics
What is the effect of cardiac glycosides? - ANSWER -Digitalis glycosides have a negative
chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
ANSWER -Medroxyprogesterone (Depo-Provera)
, What is an anti-hypertensive agent which competes with epinephrine for available beta-
receptor sites? - ANSWER -Atenolol (Tenormin)
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin
therapy? - ANSWER -To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - ANSWER -
Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level with? -
ANSWER -Propanolol (Inderal)
What type of action does nitrates have on the body? - ANSWER -Reduction in systemic
venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with
known coronary artery disease? - ANSWER -100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - ANSWER -Depressing phase 4
depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones
and re-establish eumetabolic state in a patient with Graves' disease? - ANSWER -Anti-
thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal
insufficiency? - ANSWER -Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart
failure? - ANSWER -Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? -
ANSWER -Methyldopa (Aldomet)
