Cellular Pathophysiology
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1. types of cellular adaptation atrophy, hypertrophy, hyperplasia, metaplasia, dysplasia
2. what are some etiologies to ischemia
atrophy?
3. ischemia Lack of blood supply
4. why do we often need to it shrinks the adrenals as it is derived from cortisol, so adrenals
taper patients off of pred- aren't secreting it
nisone?
5. hypertrophy increase in the size of the cells
6. hypertrophy often occurs in increased work load
response to:
7. hyperplasia increase in number of cells
8. increased age in males typ- enlarged prostate (hyperplasia)
ically indicates a higher risk
of:
9. metaplasia replacement of one cell type with another
10. examples of metaplasia: chronic smokers: simple columnar epithelium is replaced by strat-
ified squamous epithelium
*no cilia/goblet cells which push mucus out
11. dysplasia abnormal development or growth of cells, tissues, or organs
- possible precursor to cancer
12. what are some morphologic - ribosome dissociation from RER
changes resulting from cel- - mitochondrial swelling
lular injury? - pyknosis
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