NR546 Week 4 Midterm Exam 2026:
150 Practice Questions & Answers
with Rationale - Complete PMHNP
Study Guide
## Section 1: Functional Neuroanatomy (Questions 1-20)
### Question 1
A patient recovering from a stroke has trouble with speech
comprehension. Which brain area has most likely been affected?
A) Broca's area
B) Wernicke's area
C) Basal ganglia
D) Limbic system
**Answer: B) Wernicke's area**
,**Rationale:** Wernicke's area is associated with speech
comprehension. Damage results in receptive aphasia (inability to
understand language). Broca's area is associated with speech
production, not comprehension .
---
### Question 2
The amygdala is primarily associated with which function?
A) Executive function and decision-making
B) Anxiety and emotional regulation
C) Motor coordination and balance
D) Speech comprehension
**Answer: B) Anxiety and emotional regulation**
**Rationale:** The amygdala is involved in emotional regulation,
anxiety, perception of odors, and the fear response that triggers the
fight-or-flight reflex. All smells travel directly to the amygdala .
---
,### Question 3
How does the orbitofrontal cortex (OFC) affect the amygdala?
A) It only activates the amygdala
B) It only inhibits the amygdala
C) It inhibits and activates the amygdala
D) It has no effect on the amygdala
**Answer: C) It inhibits and activates the amygdala**
**Rationale:** The OFC is involved in decision-making and social
behavior with focus on punishment and rewards. The OFC both inhibits
and activates the amygdala and is activated when risk assessment is
required .
---
### Question 4
Which brain structure is most associated with memory and anxiety?
A) Amygdala
B) Hippocampus
C) Prefrontal cortex
, D) Thalamus
**Answer: B) Hippocampus**
**Rationale:** The hippocampus is involved in anxiety, memory, and
shifting short-term to long-term memory. Hippocampal function is
impaired in schizophrenia and dementia .
---
### Question 5
The limbic system is associated with which functions?
A) Motor coordination only
B) Emotion and learning
C) Speech production
D) Visual processing
**Answer: B) Emotion and learning**
**Rationale:** The limbic system is a complex set of structures
involved in emotion, learning, and memory formation .
150 Practice Questions & Answers
with Rationale - Complete PMHNP
Study Guide
## Section 1: Functional Neuroanatomy (Questions 1-20)
### Question 1
A patient recovering from a stroke has trouble with speech
comprehension. Which brain area has most likely been affected?
A) Broca's area
B) Wernicke's area
C) Basal ganglia
D) Limbic system
**Answer: B) Wernicke's area**
,**Rationale:** Wernicke's area is associated with speech
comprehension. Damage results in receptive aphasia (inability to
understand language). Broca's area is associated with speech
production, not comprehension .
---
### Question 2
The amygdala is primarily associated with which function?
A) Executive function and decision-making
B) Anxiety and emotional regulation
C) Motor coordination and balance
D) Speech comprehension
**Answer: B) Anxiety and emotional regulation**
**Rationale:** The amygdala is involved in emotional regulation,
anxiety, perception of odors, and the fear response that triggers the
fight-or-flight reflex. All smells travel directly to the amygdala .
---
,### Question 3
How does the orbitofrontal cortex (OFC) affect the amygdala?
A) It only activates the amygdala
B) It only inhibits the amygdala
C) It inhibits and activates the amygdala
D) It has no effect on the amygdala
**Answer: C) It inhibits and activates the amygdala**
**Rationale:** The OFC is involved in decision-making and social
behavior with focus on punishment and rewards. The OFC both inhibits
and activates the amygdala and is activated when risk assessment is
required .
---
### Question 4
Which brain structure is most associated with memory and anxiety?
A) Amygdala
B) Hippocampus
C) Prefrontal cortex
, D) Thalamus
**Answer: B) Hippocampus**
**Rationale:** The hippocampus is involved in anxiety, memory, and
shifting short-term to long-term memory. Hippocampal function is
impaired in schizophrenia and dementia .
---
### Question 5
The limbic system is associated with which functions?
A) Motor coordination only
B) Emotion and learning
C) Speech production
D) Visual processing
**Answer: B) Emotion and learning**
**Rationale:** The limbic system is a complex set of structures
involved in emotion, learning, and memory formation .
