Question 1
Which of the following is released into the bloodstream in the event of tumor lysis
syndrome?
Uric acid
Sodium
Magnesium
Calcium
ANSWER
Uric acid
Answer: Tumor lysis syndrome is a massive, sudden release of cellular contents in to the
bloodstream resulting in elevated uric acid levels.
Reference: Kaplan, M. (Ed.). (2013). Understanding and managing oncologic emergencies: A
resource for nurses (2nd ed.). Pittsburgh, PA: Oncology Nursing Society, p. 440.
Question 2
Which of the following cancers is associated with the development of disseminated
intravascular coagulation?
Mucin-secreting adenocarcinoma of the breast
Nonhyperdiploid variant multiple myeloma
Primary peritoneal carcinoma
1
, Acral lentiginous melanoma
ANSWER
Mucin-secreting adenocarcinoma of the breast
Answer: The incidence of disseminated intravascular coagulation is associated mostly with
mucin-secreting adenocarcinomas of the prostate, lung, and breast.
Reference: Kaplan, M. (Ed.). (2013). Understanding and managing oncologic emergencies: A
resource for nurses (2nd ed.). Pittsburgh, PA: Oncology Nursing Society, p. 69.
Question 3
Which of the following classes of medication will most significantly increase the risk for the
development of a cytokine-release syndrome reaction?
Monoclonal antibodies
Taxanes
Platinum compounds
Anthracyclines
ANSWER
Monoclonal antibodies
Answer: Monoclonal antibodies can cause cytokine-release syndrome.
Reference: Newton, S., Hickey, M., & Marrs, J. (2017). Mosby's oncology nursing advisor: A
comprehensive guide to clinical practice (2nd ed.). St. Louis, MO: Elsevier Mosby, p. 243.
Question 4
2
Which of the following is released into the bloodstream in the event of tumor lysis
syndrome?
Uric acid
Sodium
Magnesium
Calcium
ANSWER
Uric acid
Answer: Tumor lysis syndrome is a massive, sudden release of cellular contents in to the
bloodstream resulting in elevated uric acid levels.
Reference: Kaplan, M. (Ed.). (2013). Understanding and managing oncologic emergencies: A
resource for nurses (2nd ed.). Pittsburgh, PA: Oncology Nursing Society, p. 440.
Question 2
Which of the following cancers is associated with the development of disseminated
intravascular coagulation?
Mucin-secreting adenocarcinoma of the breast
Nonhyperdiploid variant multiple myeloma
Primary peritoneal carcinoma
1
, Acral lentiginous melanoma
ANSWER
Mucin-secreting adenocarcinoma of the breast
Answer: The incidence of disseminated intravascular coagulation is associated mostly with
mucin-secreting adenocarcinomas of the prostate, lung, and breast.
Reference: Kaplan, M. (Ed.). (2013). Understanding and managing oncologic emergencies: A
resource for nurses (2nd ed.). Pittsburgh, PA: Oncology Nursing Society, p. 69.
Question 3
Which of the following classes of medication will most significantly increase the risk for the
development of a cytokine-release syndrome reaction?
Monoclonal antibodies
Taxanes
Platinum compounds
Anthracyclines
ANSWER
Monoclonal antibodies
Answer: Monoclonal antibodies can cause cytokine-release syndrome.
Reference: Newton, S., Hickey, M., & Marrs, J. (2017). Mosby's oncology nursing advisor: A
comprehensive guide to clinical practice (2nd ed.). St. Louis, MO: Elsevier Mosby, p. 243.
Question 4
2
