Know what a painful muscle spasm with neck muscles pulling a patient's head to the
side called and Name a common drug therapy to relieve this symptom.
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·Torticollis or Acute Dystonic
The common drug therapy is Cogentin (Benztropine) relieves the
symptoms
Benadryl or Ativan can also be used.
Compare and contrast Neuroleptic Malignant Syndrome (NMS) to Serotonin
Syndrome. Know the key symptoms of each syndrome. What lab values may be
elevated with NMS? What medications are associated with the development of each
syndrome? How is each syndrome treated?
Give this one a try later!
, >Neuroleptic Malignant Syndrome (NMS)
· Stiffness, rigidity
· Elevated CK
· Elevated WBC
· Fever
· Develops over days or weeks
· Meds: Haldol, Thorazine, Prolixin, Stelazine.
· Resolution of NMS = Average of 9 days.
· Txmt: Hold all antipsychotics & notify MD.; Administer Dopamine agonist
drugs (Bromocriptine) and muscle relaxants (Dantrolene and Benzos);
Hydration, Safety
>Serotonin Syndrome
· High body temperature
· Dilated pupils
· Agitation
· Diarrhea
· Increase reflexes
· Myoclonus
· Tremors
· Ataxia
· Sweating
· Nausea and vomiting
· Occurs/Onset within 24 hours
· Typically caused by use of 2 or more serotonergic drugs, SSRI, MAOI,
TCA, Amphetamines
· Labs: None
· Resolution of Serotonin Syndrome <24 hours
· Treatment: Supportive Care, increase Oxygen to >94% sat, I.V. crystalloid
to treat volume depletion; Use benzos to sedate; Need ICU care.
Know whether a patient is demonstrating efficacy to clozapine 500 mg/day if this
week's granulocyte count is less than 500mm3. What is the most appropriate
recommendation for drug therapy?
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, Stop the drug, because of the risk of agranulocytosis and patient can be
infected.
The most appropriate recommendation for drug therapy is to repeat CBC
weekly.
> 1500, watch carefully if is at 1000
What population across the lifespan are most at risk for suicide? How does your
health, gender, and genetics play a role in being at a higher risk for suicide?
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· Most risk 15-24 and >65 (age)
· Most risk Young, elderly, Caucasian males
· Depression
· *Serious physical illness
· Schizophrenia 5% of suicides; other mental disorders increase risk 5-10%.
What are some factors that may increase the risk for suicide? Protective factors?
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side called and Name a common drug therapy to relieve this symptom.
Give this one a try later!
·Torticollis or Acute Dystonic
The common drug therapy is Cogentin (Benztropine) relieves the
symptoms
Benadryl or Ativan can also be used.
Compare and contrast Neuroleptic Malignant Syndrome (NMS) to Serotonin
Syndrome. Know the key symptoms of each syndrome. What lab values may be
elevated with NMS? What medications are associated with the development of each
syndrome? How is each syndrome treated?
Give this one a try later!
, >Neuroleptic Malignant Syndrome (NMS)
· Stiffness, rigidity
· Elevated CK
· Elevated WBC
· Fever
· Develops over days or weeks
· Meds: Haldol, Thorazine, Prolixin, Stelazine.
· Resolution of NMS = Average of 9 days.
· Txmt: Hold all antipsychotics & notify MD.; Administer Dopamine agonist
drugs (Bromocriptine) and muscle relaxants (Dantrolene and Benzos);
Hydration, Safety
>Serotonin Syndrome
· High body temperature
· Dilated pupils
· Agitation
· Diarrhea
· Increase reflexes
· Myoclonus
· Tremors
· Ataxia
· Sweating
· Nausea and vomiting
· Occurs/Onset within 24 hours
· Typically caused by use of 2 or more serotonergic drugs, SSRI, MAOI,
TCA, Amphetamines
· Labs: None
· Resolution of Serotonin Syndrome <24 hours
· Treatment: Supportive Care, increase Oxygen to >94% sat, I.V. crystalloid
to treat volume depletion; Use benzos to sedate; Need ICU care.
Know whether a patient is demonstrating efficacy to clozapine 500 mg/day if this
week's granulocyte count is less than 500mm3. What is the most appropriate
recommendation for drug therapy?
Give this one a try later!
, Stop the drug, because of the risk of agranulocytosis and patient can be
infected.
The most appropriate recommendation for drug therapy is to repeat CBC
weekly.
> 1500, watch carefully if is at 1000
What population across the lifespan are most at risk for suicide? How does your
health, gender, and genetics play a role in being at a higher risk for suicide?
Give this one a try later!
· Most risk 15-24 and >65 (age)
· Most risk Young, elderly, Caucasian males
· Depression
· *Serious physical illness
· Schizophrenia 5% of suicides; other mental disorders increase risk 5-10%.
What are some factors that may increase the risk for suicide? Protective factors?
Give this one a try later!
