EXAM 2
Psychopharmacology
Actual Questions with Verified Answers
Wilkes University
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➢100 Exam Questions w/ Answers
➢Expert Rationales included.
➢Exam 2 Comprehensive Study Guide
,Table of Contents
NSG 552 Exam 2 .................................................... 2
NSG 552 Exam 2 Study Guide ............................. 45
NSG 552 Exam 2
Question 1 [Case-Based Scenario]
A 22-year-old female with Anorexia Nervosa is admitted to an inpatient
psychiatric unit. She reports severe anxiety before meals and refuses to eat
due to intense fear of weight gain. The psychiatrist considers pharmacologic
intervention. Which medication is most appropriate to administer as a pre-
meal anxiolytic to decrease anticipatory anxiety?
• A. Fluoxetine 20 mg daily
• B. Lorazepam 0.5 mg PRN before meals
• C. Olanzapine 5 mg daily
• D. Buspirone 10 mg BID
Correct Answer: B. Lorazepam 0.5 mg PRN before meals
Rationale: Lorazepam is a short-acting benzodiazepine commonly used as a pre-
meal anxiolytic in Anorexia Nervosa to reduce anticipatory anxiety. It has a rapid
onset and can be given PRN. SSRIs like fluoxetine take weeks to work and are not
appropriate for acute anxiety. Olanzapine is used for severe preoccupation with
weight and food, not acute anxiety. Buspirone has a slow onset and is not useful for
PRN anxiety relief.
,Question 2 [Select All That Apply (SATA)]
A 19-year-old female with Anorexia Nervosa has been hospitalized for severe
malnutrition and obsessive preoccupation with food and body weight. Her
BMI is 14.2. The treatment team is considering pharmacologic options. Select
all that apply regarding appropriate medication management for this patient.
• A. Olanzapine may be prescribed to reduce severe preoccupation with weight
and food
• B. Fluoxetine is FDA-approved for Anorexia Nervosa
• C. A pre-meal benzodiazepine such as lorazepam may reduce anticipatory
anxiety
• D. Bupropion is contraindicated due to seizure risk in malnourished patients
• E. Mirtazapine is first-line for weight restoration in Anorexia Nervosa
Correct Answer: A, C, D
Rationale: Olanzapine (A) is used off-label for severe preoccupation with weight
and food in Anorexia Nervosa. A pre-meal benzodiazepine like lorazepam (C) can
help with anticipatory anxiety. Bupropion (D) is contraindicated in eating disorders
due to increased seizure risk, especially in malnourished patients. Fluoxetine (B) is
NOT FDA-approved for Anorexia Nervosa—it is approved for Bulimia Nervosa.
Mirtazapine (E) is not first-line for weight restoration, though it may be used
adjunctively.
Question 3 [Single Best Answer]
Which of the following medications is FDA-approved for the treatment of
Bulimia Nervosa?
• A. Sertraline (Zoloft)
• B. Fluoxetine (Prozac)
• C. Venlafaxine (Effexor)
• D. Bupropion (Wellbutrin)
Correct Answer: B. Fluoxetine (Prozac)
Rationale: Fluoxetine (Prozac) is the only FDA-approved medication for Bulimia
Nervosa. It is typically prescribed at higher doses (60 mg/day). Bupropion is
contraindicated in eating disorders due to seizure risk.
, Question 4 [Case-Based Scenario]
A 28-year-old male presents with recurrent episodes of binge eating followed
by purging behaviors. He reports feelings of shame and guilt. His vital signs
are stable, and his BMI is within normal range. Which combination represents
the most evidence-based treatment approach?
• A. Fluoxetine monotherapy only
• B. CBT-E plus fluoxetine
• C. Olanzapine plus dietary counseling
• D. Bupropion plus interpersonal therapy
Correct Answer: B. CBT-E plus fluoxetine
Rationale: The gold standard treatment for Bulimia Nervosa is Cognitive Behavioral
Therapy (CBT-E) combined with fluoxetine, the FDA-approved medication. CBT
addresses the behavioral and cognitive components, while fluoxetine targets
depressive and obsessive symptoms. Olanzapine is not indicated for bulimia.
Bupropion is contraindicated.
Question 5 [Single Best Answer]
What is the first-line treatment for Binge Eating Disorder (BED)?
• A. Lisdexamfetamine (Vyvanse)
• B. Cognitive Behavioral Therapy (CBT-E/CBT-BED)
• C. Fluoxetine (Prozac)
• D. Orlistat (Alli)
Correct Answer: B. Cognitive Behavioral Therapy (CBT-E/CBT-BED)
Rationale: CBT-E/CBT-BED is the first-line treatment for Binge Eating Disorder.
While lisdexamfetamine is FDA-approved for BED, psychotherapy remains the
initial treatment of choice. Medications are considered when psychotherapy alone is
insufficient.
Question 6 [Single Best Answer]
Which stimulant medication is FDA-approved for the treatment of Binge
Eating Disorder?