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HESI RN Pharmacology V3 – 2026/2027 NGN Prep PDF | 165 Verified Qs

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Verified HESI RN Pharmacology V3 PDF with 3 exam sets (55 questions each) featuring NGN‑style multiple‑choice and case study questions. Includes rationales for ACE inhibitors, antidepressants, insulin therapy, antibiotics, anticoagulants, and pain management. Tailored for 2026/2027 nursing students preparing for RN HESI Exit and NCLEX NGN success.

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HESI RN PHARMACOLOGY
V3 EXAM (3 Set Exams)
(NGN style Qs & Case studies)
Actual Qs & Ans to Pass the Exam


This hesi test contains:
passing score Guarantee
Each Exam has 55 Ques and Ans
Format Set of Multiple-choice
questions with incorporating Next Generation
NCLEX (NGN) and Case studies questions
Expert-Verified Explanations & Solutions

,Contents
HESI RN PHARMACOLOGY V3 EXAM ........................ 2

SET 1 .................................................................................... 2

HESI RN PHARMACOLOGY V3 EXAM ......................52

SET 2 ................................................................................. 52

HESI RN PHARMACOLOGY V3 EXAM ......................98

SET 3 ................................................................................. 98




HESI RN PHARMACOLOGY V3 EXAM


SET 1

──────────────────────────────────────────────────────

1) CASE STUDY (NGN-Style Question)

,───────────────────────────────────────────────────────



Q1. A 54-year-old client with hypertension (HTN) and type 2 diabetes mellitus (T2DM)

is preparing to take the first dose of captopril. His daily medications include

spironolactone 25 mg/day, metformin 500 mg twice a day, and insulin glargine 25

units daily. The nurse outlines several instructions:



• Instruction 1: Increase the insulin glargine dose by 3 units on the morning of the first

dose.

• Instruction 2: Limit fluids for several days before the first dose.

• Instruction 3: Lie down if blood pressure drops quickly after the first dose.

• Instruction 4: Monitor blood pressure for several hours after the first dose.

• Instruction 5: Hold spironolactone for 3 days prior to the first dose.



Question: For each nursing instruction below, indicate if it is Indicated

(safe/appropriate) or Contraindicated (unsafe/inappropriate) for a client starting

captopril.



A. 1 and 2 are Indicated; 3, 4, 5 are Contraindicated

B. 1, 2, 5 are Contraindicated; 3, 4 are Indicated

C. 1, 4 are Indicated; 2, 3, 5 are Contraindicated

D. 3, 5 are Indicated; 1, 2, 4 are Contraindicated

, Answer: B (Instructions #1, #2, #5 = Contraindicated; Instructions #3, #4 = Indicated)



Expert-Verified Explanation:

• Instruction 1 (increasing insulin without proven need) is contraindicated.

• Instruction 2 (limiting fluids pre–first-dose ACE inhibitor) is contraindicated: risk of

dehydration and severe hypotension.

• Instruction 3 (lie down if BP drops) is indicated for safety after first-dose hypotension.

• Instruction 4 (monitor BP for several hours) is indicated to assess first-dose

hypotension.

• Instruction 5 (hold spironolactone for 3 days) is not routinely required unless

hyperkalemia is an active concern.



───────────────────────────────────────────────────────



2)

───────────────────────────────────────────────────────



Q2. A client with major depression is receiving a new prescription for duloxetine.

Which information is MOST important for the nurse to obtain?



A. Family history of mental illness

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