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AORN Periop 101 Comprehensive Practice Exam (2026–2027 Study Edition)
Original Practice Questions with Answers and Rationales
Table of Contents
Section Topic
I Introduction to Perioperative Nursing
II Surgical Safety and Patient Identification
III Aseptic Technique and Infection Prevention
IV Sterile Processing and Surgical Instruments
V Surgical Positioning and Patient Safety
VI Anesthesia and Perioperative Care
VII Medication Safety in the OR
VIII Applied Clinical Scenarios
IX Review Questions
X Answer Key and Rationales
Section I: Introduction to Perioperative Nursing
Multiple Choice Questions
1. The primary responsibility of the perioperative registered nurse is to:
A. Assist the surgeon with technical procedures
B. Advocate for patient safety throughout the surgical experience
,C. Manage hospital billing procedures
D. Perform all anesthesia-related tasks
Correct Answer: B
Rationale:
The perioperative nurse’s central role is patient advocacy, ensuring safe, ethical, and evidence-
based care before, during, and after surgery.
2. The perioperative continuum includes which phases?
A. Diagnosis, treatment, discharge
B. Preoperative, intraoperative, postoperative
C. Admission, surgery, billing
D. Assessment, medication, rehabilitation
Correct Answer: B
Rationale:
Perioperative care consists of three major phases: preoperative preparation, intraoperative care,
and postoperative recovery.
3. The circulating nurse primarily functions as:
A. A sterile team member passing instruments
B. The patient advocate coordinating care inside the operating room
C. The anesthesia provider
D. The surgical assistant
Correct Answer: B
Rationale:
The circulating nurse is a nonsterile team member responsible for patient advocacy,
documentation, communication, and maintaining safety standards.
4. The scrub person’s primary responsibility is to:
A. Manage operating room scheduling
B. Maintain the sterile field and provide instruments
C. Obtain surgical consent
D. Transport patients to recovery
,Correct Answer: B
Rationale:
The scrub role focuses on sterile technique, instrumentation, supplies, and assisting the surgical
team within the sterile field.
5. A key characteristic of professional perioperative nursing practice is:
A. Working independently without communication
B. Following surgeon preference only
C. Using evidence-based standards and teamwork
D. Avoiding documentation during procedures
Correct Answer: C
Rationale:
Safe perioperative care depends on evidence-based practice, communication, teamwork, and
accurate documentation.
Short Answer Questions
6. Define the role of the perioperative nurse as a patient advocate.
Answer:
A perioperative nurse protects the patient’s rights, safety, dignity, and well-being throughout the
surgical experience.
Rationale:
Patients under anesthesia cannot advocate for themselves, making the nurse responsible for
protecting their interests.
7. Explain why communication is critical in the operating room.
Answer:
Effective communication reduces errors, improves teamwork, and promotes safe patient
outcomes.
Rationale:
Many surgical complications are associated with communication failures between healthcare
team members.
, Scenario-Based Questions
8. A patient arrives in the OR and states they are unsure which procedure they are
scheduled for. What should the circulating nurse do first?
A. Continue preparing the patient
B. Ask the surgeon after incision
C. Stop and verify the procedure using safety protocols
D. Ask another nurse what the procedure is
Correct Answer: C
Rationale:
Any uncertainty regarding patient identity, procedure, or surgical site requires stopping and
resolving the issue before proceeding.
9. During surgery, the sterile field becomes contaminated. The scrub nurse notices the
issue. What is the appropriate action?
A. Ignore it if the procedure is almost complete
B. Notify the team and correct the contamination immediately
C. Cover the contaminated area with a towel
D. Document it after surgery only
Correct Answer: B
Rationale:
Breaks in sterile technique must be immediately recognized, communicated, and corrected.
Section II: Surgical Safety and Patient Identification
Multiple Choice Questions
10. The purpose of the surgical time-out is to:
A. Reduce operating room turnover time
B. Confirm the correct patient, procedure, and site
C. Allow staff breaks
D. Review financial information
Correct Answer: B
Rationale:
The surgical time-out prevents wrong-patient, wrong-site, and wrong-procedure events.