2026/2027 Edition | 250 Verified Questions
RN Comprehensive Predictor 2026-2027 QUESTIONS AND ANSWERS ALREADY GRADED A+. 100% Verified
Solutions | Updated Per Latest Guidelines | Graded A+
This document provides 250 verified questions and answers for the ATI RN Comprehensive Predictor
Exam, aligned with the 2026/2027 academic year. It covers all core nursing domains to help candidates
assess their readiness for the NCLEX-RN. Each question includes detailed rationales and
evidence-based explanations, ensuring comprehensive preparation for a high score.
Abstract:
The RN Comprehensive Predictor Exam is a critical assessment for nursing candidates seeking licensure. This
document contains 250 questions meticulously verified to align with the ATI 2026/2027 blueprint. Questions span
fundamental nursing concepts, medical-surgical care, maternal-newborn health, pediatrics, psychiatric nursing,
pharmacology, and leadership. Each answer is accompanied by a rationale that explains correct and incorrect
choices, citing current nursing standards. The material is designed to simulate the exam experience and identify
knowledge gaps. Emphasis is placed on clinical judgment, prioritization, and safe practice. This resource is
essential for candidates aiming to achieve a high score and demonstrate competence across all nursing domains.
Content Area Overview:
Content Area Questions Key Topics Weight
Medical-Surgical Nursing 1-80 Cardiovascular, Respiratory, 32%
Gastrointestinal, Renal, Endocrine
Maternal-Newborn and Women's 81-120 Antepartum, Intrapartum, Postpartum, 16%
Health Newborn Care
Pediatric Nursing 121-160 Growth and Development, Infectious 16%
Diseases, Chronic Conditions, Safety
Psychiatric Mental Health 161-200 Mood Disorders, Anxiety, Psychosis, 16%
Nursing Substance Abuse
Pharmacology and Dosage 201-230 Medication Administration, Dosage 12%
Calculations Calculations, Drug Interactions, IV Therapy
Leadership and Management 231-250 Delegation, Prioritization, Patient Advocacy, 8%
Ethics
Page 1
,Q1. A charge nurse is making assignments for the next shift. Which client should be assigned to the
most experienced nurse?
A. Client with a new colostomy requiring discharge teaching
B. Client receiving a continuous heparin infusion for deep vein thrombosis
C. Client with pneumonia and a history of falls
D. Client with a stage III pressure injury needing wound care
Correct Answer: B. Client receiving a continuous heparin infusion for deep vein thrombosis
Rationale: The client on a continuous heparin infusion requires close monitoring for signs of bleeding,
frequent lab draws (aPTT), and dose adjustments. This high-acuity, high-risk situation demands the most
experienced nurse to ensure safe anticoagulation management. The other clients, while important, have
more stable or predictable care needs.
Why Wrong:
A - Teaching a new colostomy, though important, can be accomplished with moderate experience
and does not involve immediate life-threatening risks.
C - Pneumonia with fall risk requires vigilance but is a common condition managed by nurses of
varying experience levels.
D - Wound care for a stage III pressure injury, though specialized, is typically within the scope of
nurses with intermediate experience.
Reference: NCSBN (2026). Management of Care: Delegation and Assignment. In: NCLEX-RN Test Plan.
Q2. A nurse is preparing to care for a client with a suspected Clostridium difficile infection. Which
transmission-based precautions should the nurse initiate?
A. Contact precautions
B. Droplet precautions
C. Airborne precautions
D. Protective environment
Correct Answer: A. Contact precautions
Rationale: C. difficile is a spore-forming bacterium that spreads via fecal-oral route, requiring contact
precautions (gown and gloves) to prevent transmission to other patients. Droplet and airborne
precautions are for respiratory pathogens; protective environment is for immunocompromised patients.
Why Wrong:
B - Droplet precautions are used for agents spread by large droplets, such as influenza, not for
spore-forming gastrointestinal pathogens.
C - Airborne precautions (N95, negative pressure) are for tuberculosis, measles, varicella, not for C.
difficile.
D - Protective environment (positive pressure) is for neutropenic patients, not for infectious patients.
Reference: CDC (2025). Guideline for Isolation Precautions: Preventing Transmission of Infectious
Agents in Healthcare Settings.
Page 2
,Q3. A nurse is evaluating a client receiving bisphosphonate therapy. Which adverse effect warrants
immediate notification of the provider?
A. Hypocalcemia
B. Jaw pain
C. Gastrointestinal upset
D. Back pain
Correct Answer: B. Jaw pain
Rationale: Jaw pain may indicate osteonecrosis of the jaw, a rare but serious complication of
bisphosphonate therapy that requires prompt evaluation. Hypocalcemia occurs but is usually
asymptomatic; GI upset and back pain are common and less urgent.
Why Wrong:
A - Hypocalcemia can occur but is often mild and asymptomatic; supplementation is typically
managed orally.
C - Gastrointestinal upset (dyspepsia, esophagitis) is a known side effect but is managed with
administration instructions.
D - Back pain may be due to fractures or other causes, but is not specific to bisphosphonates and
often not immediately life-threatening.
Reference: Lehne, R.A. (2026). Pharmacology for Nursing Care, 12th Ed., Ch. 44: Bisphosphonates.
Q4. A client with a history of chronic pain is receiving an opioid analgesic and requests higher
doses. The client appears sedated. What is the nurse's priority action?
A. Administer the requested dose as needed
B. Assess the client's pain level
C. Consult the provider about changing the medication
D. Encourage nonpharmacological interventions
Correct Answer: B. Assess the client's pain level
Rationale: Before adjusting medication, the nurse must assess the pain level using a standardized scale.
Sedation could indicate overmedication or undermedication; assessment clarifies whether pain is
uncontrolled or if there is opioid-induced sedation. Administering more could worsen sedation; changing
the medication is premature without assessment.
Why Wrong:
A - Administering more opioid without assessment could lead to respiratory depression, especially if
sedation is present.
C - Consulting the provider is important but should follow assessment; the provider will need pain
rating to make a decision.
D - Nonpharmacological interventions are complementary but do not replace the need for pain
assessment and potential medication adjustment.
Reference: Pasero, C. & McCaffery, M. (2025). Pain Assessment and Pharmacologic Management, 3rd
Ed., Ch. 7.
Page 3
, Q5. A nurse is assessing a new colostomy. The stoma appears dusky (blue-tinged) and mildly
edematous. Which action should the nurse take?
A. Apply an ice pack to reduce edema
B. Document the finding as normal
C. Notify the provider immediately
D. Change the ostomy appliance
Correct Answer: C. Notify the provider immediately
Rationale: A dusky stoma indicates compromised blood flow (ischemia) and is an emergency. Edema is
common postoperatively, but duskiness is not. The provider must be notified immediately to prevent
necrosis. Ice packs can worsen ischemia; documentation alone delays intervention; changing the
appliance is unrelated.
Why Wrong:
A - Applying ice can cause vasoconstriction and worsen ischemia.
B - Duskiness is abnormal; documenting without notifying delays critical intervention.
D - Changing the appliance does not address the underlying ischemia and may cause trauma.
Reference: Wound, Ostomy and Continence Nurses Society (2025). Ostomy Management: Best Practice
for Clinicians.
Q6. A nurse is to infuse 1000 mL of 0.9% sodium chloride over 8 hours. The drop factor is 15
gtt/mL. What is the correct drip rate in gtt/min? (Round to the nearest whole number.)
A. 31 gtt/min
B. 42 gtt/min
C. 20 gtt/min
D. 63 gtt/min
Correct Answer: A. 31 gtt/min
Rationale: First calculate mL/hr: 1000 mL / 8 hr = 125 mL/hr. Then gtt/min = (125 mL/hr × 15 gtt/mL) /
60 min = 31.25 31 gtt/min. Option B results from dividing by 30 instead of 60; C from using 10 drop
factor; D from multiplying by 4 incorrectly.
Why Wrong:
B - 42 gtt/min would result from incorrectly using 30 mins as divisor.
C - 20 gtt/min corresponds to a drop factor of 10 gtt/mL.
D - 63 gtt/min is double the correct rate, likely from forgetting to divide by 60.
Reference: Buchholz, S. (2026). Math for Nurses, 11th Ed., Ch. 10: IV Flow Rates.
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