ATI Pharmacology Practice Exam 150
Questions with Answers and Rationales
EXAM REVIEWS WITH COMPLETE ACTUAL
EXAM2025-2026 QUESTIONS AND
CORRECT VERIFIED ANSWERS/ ALREADY
GRADED A+ (MOST RECENT!!)
1. A nurse is teaching a client about nitroglycerin tablets. Which
instruction is correct?
A. Swallow the tablet with water.
B. Store tablets in a weekly pill organizer.
C. Place the tablet under the tongue at the onset of chest pain.
D. Take the medication after meals.
Answer: C
Rationale: Sublingual nitroglycerin acts rapidly when placed under
the tongue. Swallowing delays absorption.
2. A client taking furosemide is at greatest risk for which electrolyte
imbalance?
A. Hypernatremia
B. Hypokalemia
C. Hypercalcemia
D. Hypermagnesemia
Answer: B
,Rationale: Loop diuretics increase potassium excretion, making
hypokalemia the most common electrolyte disturbance.
3. Which laboratory value should the nurse monitor for a client
receiving warfarin?
A. aPTT
B. INR
C. Platelet count
D. Bleeding time
Answer: B
Rationale: Warfarin therapy is monitored using the International
Normalized Ratio (INR).
4. Which medication is the antidote for opioid overdose?
A. Flumazenil
B. Naloxone
C. Protamine sulfate
D. Vitamin K
Answer: B
Rationale: Naloxone rapidly reverses opioid-induced respiratory
depression.
5. Which finding indicates therapeutic effectiveness of insulin
therapy?
A. Increased ketones
B. Blood glucose within target range
C. Elevated HbA1c
D. Increased thirst
,Answer: B
Rationale: The primary goal of insulin therapy is maintaining blood
glucose within the prescribed range.
6. A client taking lisinopril should be monitored for which adverse
effect?
A. Bradycardia
B. Persistent dry cough
C. Constipation
D. Hyperglycemia
Answer: B
Rationale: ACE inhibitors commonly cause a dry, persistent cough due
to increased bradykinin.
7. Which medication requires monitoring of digoxin levels?
A. Aspirin
B. Acetaminophen
C. Digoxin
D. Ibuprofen
Answer: C
Rationale: Digoxin has a narrow therapeutic index and requires
serum level monitoring.
8. A client taking metformin should temporarily stop the
medication before:
A. Routine dental cleaning
B. Influenza vaccination
, C. IV contrast administration
D. Walking exercise
Answer: C
Rationale: Metformin is held before iodinated contrast procedures to
reduce the risk of lactic acidosis.
9. Which medication is classified as a beta-blocker?
A. Losartan
B. Amlodipine
C. Metoprolol
D. Lisinopril
Answer: C
Rationale: Metoprolol selectively blocks beta-1 adrenergic receptors.
10. Which medication should never be crushed?
A. Vitamin C tablet
B. Enteric-coated aspirin
C. Calcium carbonate
D. Acetaminophen tablet
Answer: B
Rationale: Crushing enteric-coated medications destroys their
protective coating.
11. Which medication is commonly used to treat hypothyroidism?
A. Methimazole
B. Levothyroxine
Questions with Answers and Rationales
EXAM REVIEWS WITH COMPLETE ACTUAL
EXAM2025-2026 QUESTIONS AND
CORRECT VERIFIED ANSWERS/ ALREADY
GRADED A+ (MOST RECENT!!)
1. A nurse is teaching a client about nitroglycerin tablets. Which
instruction is correct?
A. Swallow the tablet with water.
B. Store tablets in a weekly pill organizer.
C. Place the tablet under the tongue at the onset of chest pain.
D. Take the medication after meals.
Answer: C
Rationale: Sublingual nitroglycerin acts rapidly when placed under
the tongue. Swallowing delays absorption.
2. A client taking furosemide is at greatest risk for which electrolyte
imbalance?
A. Hypernatremia
B. Hypokalemia
C. Hypercalcemia
D. Hypermagnesemia
Answer: B
,Rationale: Loop diuretics increase potassium excretion, making
hypokalemia the most common electrolyte disturbance.
3. Which laboratory value should the nurse monitor for a client
receiving warfarin?
A. aPTT
B. INR
C. Platelet count
D. Bleeding time
Answer: B
Rationale: Warfarin therapy is monitored using the International
Normalized Ratio (INR).
4. Which medication is the antidote for opioid overdose?
A. Flumazenil
B. Naloxone
C. Protamine sulfate
D. Vitamin K
Answer: B
Rationale: Naloxone rapidly reverses opioid-induced respiratory
depression.
5. Which finding indicates therapeutic effectiveness of insulin
therapy?
A. Increased ketones
B. Blood glucose within target range
C. Elevated HbA1c
D. Increased thirst
,Answer: B
Rationale: The primary goal of insulin therapy is maintaining blood
glucose within the prescribed range.
6. A client taking lisinopril should be monitored for which adverse
effect?
A. Bradycardia
B. Persistent dry cough
C. Constipation
D. Hyperglycemia
Answer: B
Rationale: ACE inhibitors commonly cause a dry, persistent cough due
to increased bradykinin.
7. Which medication requires monitoring of digoxin levels?
A. Aspirin
B. Acetaminophen
C. Digoxin
D. Ibuprofen
Answer: C
Rationale: Digoxin has a narrow therapeutic index and requires
serum level monitoring.
8. A client taking metformin should temporarily stop the
medication before:
A. Routine dental cleaning
B. Influenza vaccination
, C. IV contrast administration
D. Walking exercise
Answer: C
Rationale: Metformin is held before iodinated contrast procedures to
reduce the risk of lactic acidosis.
9. Which medication is classified as a beta-blocker?
A. Losartan
B. Amlodipine
C. Metoprolol
D. Lisinopril
Answer: C
Rationale: Metoprolol selectively blocks beta-1 adrenergic receptors.
10. Which medication should never be crushed?
A. Vitamin C tablet
B. Enteric-coated aspirin
C. Calcium carbonate
D. Acetaminophen tablet
Answer: B
Rationale: Crushing enteric-coated medications destroys their
protective coating.
11. Which medication is commonly used to treat hypothyroidism?
A. Methimazole
B. Levothyroxine
