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Exam Section 1: Item 1 of 50 National Board of Medical Examiners Time Remaining:
• Mark Comprehensive Basic Science Self-Assessment 4 hr 57 min 11 sec
1. A 40-year-old woman with a 25-year history of type 1 diabetes mellitus has a serum creatinine concentration of 2.5 mg/dl. A creatinine clearance test is ordered to determine the
glomerular filtration rate . This test is limited, compared to an inulin clearance test, because of which of the following properties of creatinine?
CJ A) Actively pumped into the distal convoluted tubule
B) Crosses freely into the loop of Henle
C) Reabsorbed into the collecting duct
U D) Secreted by the proximal tubule
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Exam Section 1: Item 2 of 50 National Board of Medical Examiners Time Remaining:
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2. A 10-year-old boy who was adopted from the Democratic Republic of Congo 2 weeks ago is brought to the physician for an initial examination. He appears slim, has thin extremities,
and is in no distress. His temperature is 37 .3°C (99.1 °F), pulse is 100/min, respirations are 20/min, and blood pressure is 118/68 mm Hg. The lungs are clear, and heart sounds are
normal. The abdomen is soft and nontender, and there is no hepatosplenomegaly. There are four 0.5-mm, firm , nontender nodules: two over the right iliac crest, one on the left thigh,
and one on the left knee. Examination of a skin snip from one of the nodules shows microfilariae. Which of the following is the most likely vector of this patient's infection?
A) Black fly
B) Bodylouse
u C) Cu/ex species mosquito
U D) lxodes species tick
E) Reduviid bug
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Exam Section 1: Item 3 of 50 National Board of Medical Examiners Time Remaining:
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3. A 3-year-old girl is brought to the physician for a well-child examination. She has had a flat purplish lesion that measures 2.1 cm in diameter on the right side of her face since birth.
The lesion shows large cavernous vascular channels. Which of the following is the most likely outcome of the lesion?
CJ A) Concurrent congenital heart disease
B) Local invasion
C) Malignant degeneration
U D) Necrosis and scarring
E) Spontaneous regression
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Exam Section 1: Item 4 of 50 National Board of Medical Examiners Time Remaining:
• Mark Comprehensive Basic Science Self-Assessment 4 hr 57 min 49 sec
4. At 2:00 AM , after sleeping for 5 hours, a 32-year-old man with type 2 diabetes mellitus has a decrease in serum glucose concentration to 37 mg/dl. In response to the hypoglycemia,
cortisol secreted by the adrenal cortex induces the synthesis of which of the following enzymes in the adrenal medulla?
CJ A) Acetyl-CoA carboxylase
B) Homocysteine methyltransferase
C) Methionine adenosyltransferase
U D) Methylmalonyl-CoA racemase
E) Phenylethanolamine N-methyltransferase
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