Exam Section 1: Item 1 of 50 National Board of Medical Examiners^ Time Remaining:
9 Mark Comprehensive Basic Science Self-Assessment 58 min 50 sec
1 . A 40- year- old woman at 5 months' gestation comes to the physician for amniocentesis. Resuits show a normal 46, XY karyotype of the fetus . Four months later, the newborn is delivered and
examination shows a female phenotype with mild clitoral enlargement Ultrasonography shows the presence of male but not female genital ducts . This newborn most likely has a mutation of
the gene of which of the following factors ?
A } Anti- paramesonephrrc (mullerian ) hormone
3 B ) 5 a -Reductase
0 C ) S R Y protein
O 0 ) Steroid sulfatase
J E ) Zinc finger transcription factor Wilms tumor 1
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,Exam Section 1: Item 2 of 50 National Board of Metlicai Examiners^ Time Remaining:
Comprehensive Basic Science Self-Assessment 58 min 47 sec
2 . A 16 - year- old girl with cystic fibrosis is brought to the physician because of a 3-week history of generalized weakness , numbness and tingling of her arms and fegs and difficulty walking. She
;
has not adhered to her medication regimen during the past 6 months She appears alert and oriented . Her vital signs are within normal limits. Physical examination shows bilateral weakness
and decreased deep tendon reflexes in the upper and lower extremities . She walks with an ataxic gait. The most likely cause of these findings is a deficiency of which of the following?
A ) Folic acid
O B ) Vitamin A
3 C ) Vitamin B 6 (pyridoxine)
0 0 ) Vitamin D
E ) Vitamin E
0 0 Us r 0 0
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,Exam Section 1: Item 3 of 50 National Board of Metlicai Examiners^ Time Remaining:
0 Mart Comprehensive Basic Science Self-Assessment 58 min 45 sec
3 . A 55 - year- old woman comes to the physician because of a 6 -month history of progressive shortness of breath while climbing stairs and constant fatigue. She is 163 cm ( 5 ft 4 in ) tall and
.
weighs 107 kg (235 lb); BMI is 40 kg/m2 Her blood pressure is 170/110 mm Hg on three separate readings. Physical examination shows no other abnormalities . Echocardiography shows an
ejection fraction of 45 % . There are no regional wall motion or valvular abnormalities. An EGG shows that the sum of the magnitudes of the S wave in lead V 2 and the R wave in lead V 5 is
45 mm ( scale=1G mm /mV). Which of the following ceilular changes is most likely in this patient's left ventricle compared with normal?
A ) Decreased sarcomeres and increased fibroblasts
. 8 ) Increased sarcomeres in an array in parallel with each other
3 G ) increased sarcomeres in an array in series with each other
) D ) increased sarcomeres with decreased abundance of F -actin
E ) Myocardial infiltration of neutrophils
0 0 <F 0
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, Exam Section 1: Item 4 of 50 National Board of Metlicai Examiners^ Time Remaining:
Comprehensive Basic Science Self-Assessment 58 min 42 sec
4 . A 55 - year- old man with long- standing type 2 diabetes mellitus comes to the physician because of a 2- day history of fever . chil! s: nausea and swelling of his left leg . His temperature is 38.9 X
,
(102 aF), and pulse is 110/min . Examination of the left lower extremity shows a warm tender erythematous , blanching rash . A photograph of the left tower extremity is shown . A
;
photomicrograph of a Gram stain of a blood culture is shown. Which of the following is the most likely causal organism?
A ) Clostridium perfringens
B ) Enterococcus faecalis
'
. _ G ) Haemophilus influenzae
J D ) Pasteuretla multocida
E ) Pseudomonas aeruginosa
0 F ) Staphylococcus aureus
0 G ) Streptococcus pyogenes ( group A )
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9 Mark Comprehensive Basic Science Self-Assessment 58 min 50 sec
1 . A 40- year- old woman at 5 months' gestation comes to the physician for amniocentesis. Resuits show a normal 46, XY karyotype of the fetus . Four months later, the newborn is delivered and
examination shows a female phenotype with mild clitoral enlargement Ultrasonography shows the presence of male but not female genital ducts . This newborn most likely has a mutation of
the gene of which of the following factors ?
A } Anti- paramesonephrrc (mullerian ) hormone
3 B ) 5 a -Reductase
0 C ) S R Y protein
O 0 ) Steroid sulfatase
J E ) Zinc finger transcription factor Wilms tumor 1
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(E
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,Exam Section 1: Item 2 of 50 National Board of Metlicai Examiners^ Time Remaining:
Comprehensive Basic Science Self-Assessment 58 min 47 sec
2 . A 16 - year- old girl with cystic fibrosis is brought to the physician because of a 3-week history of generalized weakness , numbness and tingling of her arms and fegs and difficulty walking. She
;
has not adhered to her medication regimen during the past 6 months She appears alert and oriented . Her vital signs are within normal limits. Physical examination shows bilateral weakness
and decreased deep tendon reflexes in the upper and lower extremities . She walks with an ataxic gait. The most likely cause of these findings is a deficiency of which of the following?
A ) Folic acid
O B ) Vitamin A
3 C ) Vitamin B 6 (pyridoxine)
0 0 ) Vitamin D
E ) Vitamin E
0 0 Us r 0 0
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,Exam Section 1: Item 3 of 50 National Board of Metlicai Examiners^ Time Remaining:
0 Mart Comprehensive Basic Science Self-Assessment 58 min 45 sec
3 . A 55 - year- old woman comes to the physician because of a 6 -month history of progressive shortness of breath while climbing stairs and constant fatigue. She is 163 cm ( 5 ft 4 in ) tall and
.
weighs 107 kg (235 lb); BMI is 40 kg/m2 Her blood pressure is 170/110 mm Hg on three separate readings. Physical examination shows no other abnormalities . Echocardiography shows an
ejection fraction of 45 % . There are no regional wall motion or valvular abnormalities. An EGG shows that the sum of the magnitudes of the S wave in lead V 2 and the R wave in lead V 5 is
45 mm ( scale=1G mm /mV). Which of the following ceilular changes is most likely in this patient's left ventricle compared with normal?
A ) Decreased sarcomeres and increased fibroblasts
. 8 ) Increased sarcomeres in an array in parallel with each other
3 G ) increased sarcomeres in an array in series with each other
) D ) increased sarcomeres with decreased abundance of F -actin
E ) Myocardial infiltration of neutrophils
0 0 <F 0
Previous Next Lab Values Calculator Review *
Help Pause
, Exam Section 1: Item 4 of 50 National Board of Metlicai Examiners^ Time Remaining:
Comprehensive Basic Science Self-Assessment 58 min 42 sec
4 . A 55 - year- old man with long- standing type 2 diabetes mellitus comes to the physician because of a 2- day history of fever . chil! s: nausea and swelling of his left leg . His temperature is 38.9 X
,
(102 aF), and pulse is 110/min . Examination of the left lower extremity shows a warm tender erythematous , blanching rash . A photograph of the left tower extremity is shown . A
;
photomicrograph of a Gram stain of a blood culture is shown. Which of the following is the most likely causal organism?
A ) Clostridium perfringens
B ) Enterococcus faecalis
'
. _ G ) Haemophilus influenzae
J D ) Pasteuretla multocida
E ) Pseudomonas aeruginosa
0 F ) Staphylococcus aureus
0 G ) Streptococcus pyogenes ( group A )
<1
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