Exam Questions and Correct
Answers | New Update
What is the MOA of antihistamines? - ANSWER ✔✔Bind to H1
histamine receptors and block their actions to reduce allergic symptoms
(swelling, itching, increased mucous)
Which of the following symptoms is NOT typically alleviated by
antihistamines? - ANSWER ✔✔nasal congestion
What are the common side effects of first-generation antihistamines? -
ANSWER ✔✔Sedation, impaired memory, dizziness, incoordination,
, confusion, visual changes, fatigue, and anticholinergic effects like dry
mouth.
Name a first-generation antihistamine. - ANSWER
✔✔Diphenhydramine (Benadryl), dimenhydrinate, and promethazine.
What are the indications for using first-generation antihistamines? -
ANSWER ✔✔Mild allergic disorders (allergic rhinitis and urticaria),
motion sickness, insomnia, and as antitussives for cough suppression.
What is paradoxical excitation in the context of first-generation
antihistamines? - ANSWER ✔✔Insomnia and nervousness (may also
indicate an overdose)
What are the anticholinergic effects associated with first-generation
antihistamines? - ANSWER ✔✔Dry mouth, dry nose, and dry throat.
What are common side effects of second-generation antihistamines? -
ANSWER ✔✔Generally well tolerated; rare effects include headache,
mild GI upset, and mild drowsiness.
Which second-generation antihistamine is known for having minimal
sedative effects? - ANSWER ✔✔Fexofenadine (Allegra)